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dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.authorXAVIER, Igor R. R.
dc.contributor.authorGIRALDI, Gilson A.
dc.contributor.authorGIBSON, Stuart James
dc.contributor.authorGATTAS, Gilka J. F.
dc.contributor.authorRUECKERT, Daniel
dc.contributor.authorTHOMAZ, Carlos E.
dc.date.accessioned2019-09-23T14:18:32Z-
dc.date.available2019-09-23T14:18:32Z-
dc.date.issued2019
dc.identifier.citationIET IMAGE PROCESSING, v.13, n.9, p.1561-1568, 2019
dc.identifier.issn1751-9659
dc.identifier.urihttps://observatorio.fm.usp.br/handle/OPI/33498-
dc.description.abstractA number of studies have been developed recently in order to explore associations between craniofacial differences and genetics. Most of these works have been based on spatial face image models, adjusted for the counter effects of age. This approach provides a limited understanding of normal and abnormal craniofacial development owing to the lack of age progression information. Here, the authors propose and implement an imaging framework that combines facial landmark positioning, non-rigid registration, novel age-dependent face modelling and common distance metrics to disclose the most facial differences that vary across the time due to the subjects' age. All the experiments carried out and corresponding results presented here are based on a database comprising ordinary two-dimensional (2D) frontal face images of Down Syndrome (DS) and control sample groups. A number of craniofacial metrics have been successfully identified that highlight statistically significant and clinically relevant differences between the controls and the faces associated with DS within the age range from 1 to 18 years old, producing realistic unbiased face models with similar level of detail at all age-intervals, despite the small sample size available.eng
dc.description.sponsorshipCAPES (PROSUC) [001]
dc.description.sponsorshipFAPESP [2012/22377-6]
dc.description.sponsorshipCNPq [309532/2014-0]
dc.description.sponsorshipNewton Advanced Fellowship [NA140147]
dc.language.isoeng
dc.publisherINST ENGINEERING TECHNOLOGY-IETeng
dc.relation.ispartofIet Image Processing
dc.rightsrestrictedAccesseng
dc.subjectimage registrationeng
dc.subjectgeneticseng
dc.subjectface recognitioneng
dc.subjectspatiotemporal phenomenaeng
dc.subjectrealistic unbiased face modelseng
dc.subjectage-intervalseng
dc.subjectage-related craniofacial differenceseng
dc.subjectspatio-temporal face image atlaseseng
dc.subjectgeneticseng
dc.subjectspatial face image modelseng
dc.subjectage progression informationeng
dc.subjectfacial landmark positioningeng
dc.subjectnonrigid registrationeng
dc.subjectage-dependent faceeng
dc.subjectfacial differenceseng
dc.subjectcraniofacial metricseng
dc.subjectdistance metricseng
dc.subjectabnormal craniofacial developmenteng
dc.subject.otherdown-syndromeeng
dc.subject.otherfacial morphologyeng
dc.titleAge-related craniofacial differences based on spatio-temporal face image atlaseseng
dc.typearticleeng
dc.rights.holderCopyright INST ENGINEERING TECHNOLOGY-IETeng
dc.identifier.doi10.1049/iet-ipr.2018.6271
dc.subject.wosComputer Science, Artificial Intelligenceeng
dc.subject.wosEngineering, Electrical & Electroniceng
dc.subject.wosImaging Science & Photographic Technologyeng
dc.type.categoryoriginal articleeng
dc.type.versionpublishedVersioneng
hcfmusp.author.externalXAVIER, Igor R. R.:Univ Ctr FEI, Dept Elect Engn, Sao Paulo, Brazil
hcfmusp.author.externalGIRALDI, Gilson A.:Natl Lab Sci Comp, Dept Comp Sci, Rio De Janeiro, Brazil
hcfmusp.author.externalGIBSON, Stuart James:Univ Kent, Sch Phys Sci, Canterbury, Kent, England
hcfmusp.author.externalRUECKERT, Daniel:Imperial Coll London, Dept Comp, London, England
hcfmusp.author.externalTHOMAZ, Carlos E.:Univ Ctr FEI, Dept Elect Engn, Sao Paulo, Brazil
hcfmusp.description.beginpage1561
hcfmusp.description.endpage1568
hcfmusp.description.issue9
hcfmusp.description.volume13
hcfmusp.origemWOS
hcfmusp.origem.idWOS:000476538300018
hcfmusp.origem.id2-s2.0-85069446066
hcfmusp.publisher.cityHERTFORDeng
hcfmusp.publisher.countryENGLANDeng
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dc.description.indexPubMedeng
dc.identifier.eissn1751-9667
hcfmusp.citation.scopus0-
hcfmusp.scopus.lastupdate2024-02-23-
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