Please use this identifier to cite or link to this item: https://observatorio.fm.usp.br/handle/OPI/33926
Full metadata record
DC FieldValueLanguage
dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.authorTRITTO, Aline C.
dc.contributor.authorBUENO, Salomao
dc.contributor.authorRODRIGUES, Rosa M. P.
dc.contributor.authorGUALANO, Bruno
dc.contributor.authorROSCHEL, Hamilton
dc.contributor.authorARTIOLI, Guilherme G.
dc.date.accessioned2019-11-06T18:45:42Z
dc.date.available2019-11-06T18:45:42Z
dc.date.issued2019
dc.identifier.citationINTERNATIONAL JOURNAL OF SPORT NUTRITION AND EXERCISE METABOLISM, v.29, n.5, p.505-511, 2019
dc.identifier.issn1526-484X
dc.identifier.urihttps://observatorio.fm.usp.br/handle/OPI/33926
dc.description.abstractThis study evaluated the effects of beta-hydroxy-beta-methylbutyrate free acid (HMB-FA) and calcium salt (HMB-Ca) on strength, hypertrophy, and markers of muscle damage. In this randomized, double-blind, placebo-controlled study, 44 resistance-trained men (age: 26 +/- 4 years; body mass: 84.9 +/- 12.0 kg) consuming = 1.7 g.kg(-1).day(-1) of protein received HMB-FA (3 g/day; n = 14), HMB-Ca (3 g/day; n = 15), or placebo (PL; cornstarch, 3 g/day; n = 15) for 12 weeks, while performing a periodized resistance training program. Before and after intervention, lean body mass (measured with dual X-ray absorptiometry), maximal dynamic strength (one-repetition maximum), knee extension maximal isometric strength (maximal voluntary isometric contraction [MVIC]), cross-sectional area (measured with ultrasound), and muscle soreness were assessed. MVIC was also measured 48 hr after the first and the last training sessions. All groups increased lean body mass (main time effect: p < .0001; HMB-FA: 1.8 +/- 1.8 kg; HMB-Ca: 0.8 +/- 1.4 kg; PL: 0.9 +/- 1.4 kg), cross-sectional area (main time effect: p < .0001; HMB-FA: 6.6 +/- 3.8%; HMB-Ca: 4.7 +/- 4.4%; PL: 6.9 +/- 3.8%), one-repetition maximum bench press (main time effect: p < .0001; HMB-FA: 14.8 +/- 8.4 kg; HMB-Ca: 11.8 +/- 7.4 kg; PL: 11.2 +/- 6.6 kg), MVIC (main time effect: p < .0001; HMB-FA: 34.4 +/- 39.3%; HMB-Ca: 32.3 +/- 27.4%; PL: 17.7 +/- 20.9%) after the intervention, but no differences between groups were shown. HMB-FA group showed greater leg press strength after the intervention than HMB-Ca and PL groups (Group x Time interaction: p < .05; HMB-FA: 47.7 +/- 31.2 kg; HMB-Ca: 43.8 +/- 31.7 kg; PL: 30.2 +/- 20.9 kg). MVIC measured 48 hr after the first and the last sessions showed no attenuation of force decline with supplementation. Muscle soreness following the first and last sessions was not different between groups. The authors concluded that neither HMB-Ca nor HMB-FA improved hypertrophy or reduced muscle damage in resistance-trained men undergoing resistance training ingesting optimal amounts of protein. HMB-FA but not HMB-Ca resulted in a statistically significant yet minor improvement on leg press one-repetition maximum.eng
dc.description.sponsorshipFAPESPFundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP) [2014/11948-8]
dc.description.sponsorshipCAPES-PROEXCAPES
dc.description.sponsorshipCAPESCAPES
dc.description.sponsorshipCoordenacao de Aperfeicoamento de Pessoal de Nivel Superior-Brazil (CAPES)CAPES [001]
dc.language.isoeng
dc.publisherHUMAN KINETICS PUBL INCeng
dc.relation.ispartofInternational Journal of Sport Nutrition and Exercise Metabolism
dc.rightsrestrictedAccesseng
dc.subjectHMBeng
dc.subjecthypertrophyeng
dc.subjectmuscle damageeng
dc.subjectsupplementationeng
dc.subjectrecoveryeng
dc.subject.otherinduced muscle damageeng
dc.subject.otherbody-compositioneng
dc.subject.otherhmb supplementationeng
dc.subject.otherpowereng
dc.subject.othermasseng
dc.subject.otherperformanceeng
dc.subject.othercreatineeng
dc.subject.otherleucineeng
dc.subject.otherproteineng
dc.titleNegligible Effects of beta-Hydroxy-beta-Methylbutyrate Free Acid and Calcium Salt on Strength and Hypertrophic Responses to Resistance Training: A Randomized, Placebo-Controlled Studyeng
dc.typearticleeng
dc.rights.holderCopyright HUMAN KINETICS PUBL INCeng
dc.identifier.doi10.1123/ijsnem.2018-0337
dc.identifier.pmid30859862
dc.subject.wosNutrition & Dieteticseng
dc.subject.wosSport Scienceseng
dc.type.categoryoriginal articleeng
dc.type.versionpublishedVersioneng
hcfmusp.author.externalTRITTO, Aline C.:Univ Sao Paulo, Appl Physiol & Nutr Res Grp, Sch Phys Educ & Sport, Sao Paulo, Brazil
hcfmusp.author.externalBUENO, Salomao:Univ Sao Paulo, Appl Physiol & Nutr Res Grp, Sch Phys Educ & Sport, Sao Paulo, Brazil
hcfmusp.author.externalROSCHEL, Hamilton:Univ Sao Paulo, Appl Physiol & Nutr Res Grp, Sch Phys Educ & Sport, Sao Paulo, Brazil
hcfmusp.author.externalARTIOLI, Guilherme G.:Univ Sao Paulo, Appl Physiol & Nutr Res Grp, Sch Phys Educ & Sport, Sao Paulo, Brazil
hcfmusp.description.beginpage505
hcfmusp.description.endpage511
hcfmusp.description.issue5
hcfmusp.description.volume29
hcfmusp.origemWOS
hcfmusp.origem.idWOS:000485198300007
hcfmusp.origem.id2-s2.0-85071782470
hcfmusp.publisher.cityCHAMPAIGNeng
hcfmusp.publisher.countryUSAeng
hcfmusp.relation.referenceBrown LE, 2001, J EXERC PHYSL ONLINE, V4, P1, DOI 10.4236/JEP.2013.46A001eng
hcfmusp.relation.referenceBuckinx F, 2018, J CACHEXIA SARCOPENI, V9, P269, DOI 10.1002/jcsm.12268eng
hcfmusp.relation.referenceDamas F, 2016, INT J SPORTS MED, V37, P633, DOI 10.1055/s-0042-100281eng
hcfmusp.relation.referenceFernandes Alan Lins, 2017, Nutrition and Health (Bicester), V23, P251, DOI 10.1177/0260106017737465eng
hcfmusp.relation.referenceFuller JC, 2011, BRIT J NUTR, V105, P367, DOI 10.1017/S0007114510003582eng
hcfmusp.relation.referenceJakubowski JS, 2019, MED SCI SPORT EXER, V51, P65, DOI 10.1249/MSS.0000000000001752eng
hcfmusp.relation.referenceJowko E, 2001, NUTRITION, V17, P558, DOI 10.1016/S0899-9007(01)00540-8eng
hcfmusp.relation.referenceKreider RB, 1999, INT J SPORTS MED, V20, P503eng
hcfmusp.relation.referenceLowery RP, 2016, J STRENGTH COND RES, V30, P1843, DOI 10.1519/JSC.0000000000000482eng
hcfmusp.relation.referenceMagal M, 2010, J SPORT SCI, V28, P257, DOI 10.1080/02640410903440892eng
hcfmusp.relation.referenceMaughan RJ, 2018, BRIT J SPORT MED, V52, P439, DOI 10.1136/bjsports-2018-099027eng
hcfmusp.relation.referenceMorton RW, 2018, BRIT J SPORT MED, V52, P376, DOI 10.1136/bjsports-2017-097608eng
hcfmusp.relation.referenceNissen S, 1996, J APPL PHYSIOL, V81, P2095eng
hcfmusp.relation.referenceNissen S, 2000, J NUTR, V130, P1937eng
hcfmusp.relation.referenceNunan D, 2010, J STRENGTH COND RES, V24, P531, DOI 10.1519/JSC.0b013e3181c4d370eng
hcfmusp.relation.referenceO'Connor DM, 2007, J STRENGTH COND RES, V21, P419, DOI 10.1519/R-15974.1eng
hcfmusp.relation.referencePhillips SM, 2017, J STRENGTH COND RES, V31, pE71, DOI 10.1519/JSC.0000000000001760eng
hcfmusp.relation.referenceRansone J, 2003, J STRENGTH COND RES, V17, P34eng
hcfmusp.relation.referenceSlater G, 2001, INT J SPORT NUTR EXE, V11, P384, DOI 10.1123/ijsnem.11.3.384eng
hcfmusp.relation.referenceTeixeira F.J., 2018, MED SCI SPORTS EXERC, V51, P56eng
hcfmusp.relation.referenceThomson JS, 2009, J STRENGTH COND RES, V23, P827, DOI 10.1519/JSC.0b013e3181a00d47eng
hcfmusp.relation.referenceVukovich MD, 2001, J NUTR, V131, P2049eng
hcfmusp.relation.referenceWilkinson DJ, 2013, J PHYSIOL-LONDON, V591, P2911, DOI 10.1113/jphysiol.2013.253203eng
hcfmusp.relation.referenceWilson JM, 2014, EUR J APPL PHYSIOL, V114, P1217, DOI 10.1007/s00421-014-2854-5eng
hcfmusp.relation.referenceWilson JM, 2013, J INT SOC SPORT NUTR, V10, DOI 10.1186/1550-2783-10-6eng
dc.description.indexMEDLINEeng
dc.identifier.eissn1543-2742
hcfmusp.citation.scopus4
hcfmusp.scopus.lastupdate2022-05-06-
Appears in Collections:

Artigos e Materiais de Revistas Científicas - FM/MCM
Departamento de Clínica Médica - FM/MCM

Artigos e Materiais de Revistas Científicas - HC/ICHC
Instituto Central - HC/ICHC

Artigos e Materiais de Revistas Científicas - LIM/17
LIM/17 - Laboratório de Investigação em Reumatologia


Files in This Item:
There are no files associated with this item.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.