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dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.authorZERBINI, Talita
dc.contributor.authorSINGER, Julio M.
dc.contributor.authorLEYTON, Vilma
dc.identifier.citationCLINICS, v.74, article ID e1197, 6p, 2019
dc.description.abstractOBJECTIVES: An objective of clinical autopsies is to determine the final cause of death and the pathological changes that may have triggered it. Despite advances in Medicine, the level of discrepancy between clinical and autopsy diagnoses remains significant. The aim of this study was to compare the data obtained from autopsies carried out at the Sao Bernardo do Campo/SP Death Verification Section with clinical diagnostic hypotheses proposed during medical care. METHOD: This was a retrospective study involving the comparison of necroscopic reports issued by the Sao Bernardo do Campo/Sao Paulo Death Verification Section in 2014 and 2015 and the Cadaver Referral Guides completed by attending physicians prior to the necroscopic examination. RESULTS: A total of 465 cases were analyzed. In general, discrepancies between the clinical diagnostic hypothesis and the autopsy diagnosis occurred in 28% of the cases. A logistic regression model, with diagnostic discrepancy as a response variable and sex, age, duration of care, type of institution providing medical care and organ system as explanatory variables, was fit to the data; the results indicated that all explanatory variables with the exception of organ system are not significant (p>0.132). CONCLUSIONS: Discrepancies between clinical diagnostic hypotheses and autopsy diagnoses continue to occur, despite new developments in complementary examinations and therapies. The odds of a discrepancy when patients present with diseases of the cardiac system are greater than those when there are problems in the vascular, endocrine and neurological systems.eng
dc.description.sponsorshipNational Council for Scientific and Technological ResearchConsejo Nacional de Investigaciones Cientificas y Tecnicas (CONICET) [CNPq 304126/2015-2]
dc.description.sponsorshipLIM-40 from the Faculdade de Medicina da Universidade de Sao Paulo
dc.subjectMedical Eerrorseng
dc.subjectCause of Deatheng
dc.titleEvaluation of the discrepancy between clinical diagnostic hypotheses and anatomopathological diagnoses resulting from autopsieseng
dc.rights.holderCopyright HOSPITAL CLINICAS, UNIV SAO PAULOeng
dc.subject.wosMedicine, General & Internaleng
dc.type.categoryoriginal articleeng
dc.type.versionpublishedVersioneng, Julio M.:Univ Sao Paulo, Inst Matemat & Estat, Sao Paulo, SP, Brazil
hcfmusp.publisher.citySAO PAULOeng
hcfmusp.relation.referenceAalten CM, 2006, NETH J MED, V64, P186eng
hcfmusp.relation.referenceEspinosa-Brito AD, 2017, MEDICC REV, V19, P37eng
hcfmusp.relation.referenceFares AF, 2011, ARQ BRAS CARDIOL, V97, P449, DOI 10.1590/S0066-782X2011005000111eng
hcfmusp.relation.referenceVal-Bernal JF, 2015, MED CLIN-BARCELONA, V145, P313, DOI 10.1016/j.medcli.2015.02.015eng
hcfmusp.relation.referenceFranca GV, 2004, MED LEGALeng
hcfmusp.relation.referenceGibson TN, 2004, J CLIN PATHOL, V57, P980, DOI 10.1136/jcp.2004.016246eng
hcfmusp.relation.referenceGrade MHC, 2004, J CLIN PATHOL, V57, P369, DOI 10.1136/jcp.2003.013235eng
hcfmusp.relation.referenceHosmer DW, 2013, WILEY SER PROBAB ST, P269eng
hcfmusp.relation.referenceKotovicz F, 2008, CLINICS, V63, P581, DOI 10.1590/S1807-59322008000500003eng
hcfmusp.relation.referenceKuijpers CCHJ, 2014, J CLIN PATHOL, V67, P512, DOI 10.1136/jclinpath-2013-202122eng
hcfmusp.relation.referenceLadich E, 2006, NAT CLIN PRACT CARD, V3, P289, DOI 10.1038/ncpcardio0581eng
hcfmusp.relation.referenceLester H, 2001, MED EDUC, V35, P855, DOI 10.1046/j.1365-2923.2001.01003.xeng
hcfmusp.relation.referenceLundstrom C, 2012, APMIS, V120, P316, DOI 10.1111/j.1600-0463.2011.02857.xeng
hcfmusp.relation.referenceMateos FPA, 2009, REA EJAUTOPSY, V7, P3eng
hcfmusp.relation.referenceMOSQUERA DA, 1993, ANN ROY COLL SURG, V75, P115eng
hcfmusp.relation.referencePastores SM, 2007, CRIT CARE, V11, DOI 10.1186/cc5782eng
hcfmusp.relation.referencePatowary AJ, 2012, NE QUEST, V6, P2eng
hcfmusp.relation.referenceRodrigues AN, 2011, CADERNOS UNIFOA, V6, P69eng
hcfmusp.relation.referenceRodrigues Fabiana Resende, 2011, J. Bras. Patol. Med. Lab., V47, P445, DOI 10.1590/S1676-24442011000400009eng
hcfmusp.relation.referenceSanders R, 2003, INTERNET J MED TECHN, V2, P1eng
hcfmusp.relation.referenceSchwanda-Burger S, 2012, MODERN PATHOL, V25, P777, DOI 10.1038/modpathol.2011.199eng
hcfmusp.relation.referenceTavora F, 2008, AM J CLIN PATHOL, V129, P102, DOI 10.1309/9M7DFE62RTDKHH4Deng
hcfmusp.relation.referenceWinters B, 2012, BMJ QUAL SAF, V21, P894, DOI 10.1136/bmjqs-2012-000803eng
hcfmusp.relation.referenceZhu KQ, 2014, PLOS ONE, V9, DOI 10.1371/journal.pone.0112500eng
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Artigos e Materiais de Revistas Científicas - FM/MLS
Departamento de Medicina Legal, Ética Médica e Medicina Social e do Trabalho - FM/MLS

Artigos e Materiais de Revistas Científicas - LIM/40
LIM/40 - Laboratório de Imunohematologia e Hematologia Forense

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