Please use this identifier to cite or link to this item: https://observatorio.fm.usp.br/handle/OPI/34681
Title: Exploratory analysis of requests for authorization to dispense high-cost medication to COPD patients: the Sao Paulo ""protocol""
Authors: CARVALHO-PINTO, Regina MariaSILVA, Ingredy Tavares daNAVACCHIA, Lucas Yoshio KidoGRANJA, Flavia MunhosMARQUES, Gustavo GarciaNERY, Telma de Cassia dos SantosFERNANDES, Frederico Leon ArrabalCUKIER, AlbertoSTELMACH, Rafael
Citation: JORNAL BRASILEIRO DE PNEUMOLOGIA, v.45, n.6, article ID e20180355, 7p, 2019
Abstract: Objective: A resolution passed by the government of the Brazilian state of Sao Paulo established a protocol for requesting free COPD medications, including tiotropium bromide, creating regional authorization centers to evaluate and approve such requests, given the high cost of those medications. Our objective was to analyze the requests received by an authorization center that serves cities in the greater metropolitan area of (the city of) Sao Paulo between 2011 and 2016. Methods: Data regarding the authorization, return, or rejection of the requests were compiled and analyzed in order to explain those outcomes. Subsequently, the clinical and functional data related to the patients were evaluated. Results: A total of 7,762 requests for dispensing COPD medication were analyzed. Requests related to male patients predominated. Among the corresponding patients, the mean age was 66 years, 12% were smokers, 88% had frequent exacerbations, and 84% had severe/very severe dyspnea. The mean FEV1 was 37.2% of the predicted value. The total number of requests decreased by 24.5% from 2012 to 2013 and was lowest in 2015. Most (65%) of the requests were accepted. The main reasons for the rejection/return of a request were a post-bronchodilator FEV1/FVC ratio > 0.7, a post-bronchodilator FEV1 > 50% of the predicted value, and failure to provide information regarding previous use of a long-acting beta(2) agonist. During the study period, the total number of requests returned/rejected decreased slightly, and there was improvement in the quality of the data included on the forms. Conclusions: Here, we have identified the characteristics of the requests for COPD medications and of the corresponding patients per region served by the authorization center analyzed, thus contributing to the improvement of local public health care measures.
Appears in Collections:

Artigos e Materiais de Revistas Científicas - HC/ICESP
Instituto do Câncer do Estado de São Paulo - HC/ICESP

Artigos e Materiais de Revistas Científicas - HC/ICHC
Instituto Central - HC/ICHC

Artigos e Materiais de Revistas Científicas - HC/InCor
Instituto do Coração - HC/InCor

Artigos e Materiais de Revistas Científicas - LIM/05
LIM/05 - Laboratório de Poluição Atmosférica Experimental

Artigos e Materiais de Revistas Científicas - LIM/09
LIM/09 - Laboratório de Pneumologia


Files in This Item:
File Description SizeFormat 
art_CARVALHO-PINTO_Exploratory_analysis_of_requests_for_authorization_to_dispense_2019.PDFpublishedVersion (English)413.26 kBAdobe PDFThumbnail
View/Open

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.