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dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.authorABUCHAM-NETO, J.Z.
dc.contributor.authorMASSON, A.P.
dc.contributor.authorNASCIMENTO, P.A.
dc.contributor.authorFERRAZ, A.A. Barbosa
dc.contributor.authorSOUZA, E. Cunha de
dc.date.accessioned2020-04-03T16:27:41Z-
dc.date.available2020-04-03T16:27:41Z-
dc.date.issued2019
dc.identifier.citationAMERICAN JOURNAL OF OPHTHALMOLOGY CASE REPORTS, v.16, article ID 100548, p, 2019
dc.identifier.issn2451-9936
dc.identifier.urihttps://observatorio.fm.usp.br/handle/OPI/35761-
dc.description.abstractPurpose: To describe a case of bilateral presumed atypical Harada disease with sequential, not simultaneous, involvement of the peripapillary retina (subretinal fluid) in a healthy patient with no systemic complaints. Observation: A 35-year-old healthy white man presented with sudden paracentral visual loss in the left eye. His medical history was unremarkable. However, he reported a similar episode 20 months earlier in the right eye that was associated with macular serous retinal detachment. The right eye showed evidence of reactive peripapillary atrophy and pigmentary alteration in the macula. Optical coherence tomography scans of the posterior left eye segment revealed a diffuse thickened choroid, papillomacular subretinal exudate and discontinuity of the ellipsoid layer with suggestion of vitreous cellularity. Autofluorescence imaging of the left eye showed peripapillary hyperautofluorescence. A fluorescein angiogram revealed progressive staining and pooling of the peripapillary retina with corresponding retinal vasculitis. Indocyanine green angiography revealed multiple hypocyanescent lesions with an area of hypercyanescence temporal to the disc. Rheumatologic evaluation and laboratory tests were all negative. Chest tomography was normal. Considering the apparent absence of infectious diseases, the patient was started on 60 mg/day prednisone. After 8 days, visual acuity improved to 20/250, improving to 20/20 vision six months after a slow steroid wean. Conclusion: We believe our case represented a variant of the Vogt-Koyanagi-Harada syndrome in an atypical situation, because the patient fulfilled the presumed criteria. Furthermore, the findings of clinical and complementary examinations led to this nosological entity to the exclusion of others. Importance: The point of this case is to alert ophthalmologists to the existence of this atypical presentation of the disease so that it should be included among the differential diagnoses of pathologies that present with these findings. © 2019 The Authorseng
dc.language.isoeng
dc.publisherELSEVIER INCeng
dc.relation.ispartofAmerican Journal of Ophthalmology Case Reports
dc.rightsopenAccesseng
dc.subjectSerous retinal detachmenteng
dc.subjectVogt-Koyanagi-Haradaeng
dc.subject.otherprednisoneeng
dc.subject.otheradulteng
dc.subject.otherarticleeng
dc.subject.othercase reporteng
dc.subject.otherchoroideng
dc.subject.otherclinical articleeng
dc.subject.otherhumaneng
dc.subject.otherindocyanine green angiographyeng
dc.subject.othermaleeng
dc.subject.otheroptical coherence tomographyeng
dc.subject.otherretina detachmenteng
dc.subject.otherretina exudateeng
dc.subject.otherretina fluorescein angiographyeng
dc.subject.otherretina macula luteaeng
dc.subject.otherretina vasculitiseng
dc.subject.othervisual acuityeng
dc.subject.othervisual impairmenteng
dc.subject.othervitreous bodyeng
dc.subject.othervogt koyanagi syndromeeng
dc.titlePresumed atypical peripapillary Vogt-Koyanagi-Harada diseaseeng
dc.typearticleeng
dc.rights.holderCopyright ELSEVIER INCeng
dc.identifier.doi10.1016/j.ajoc.2019.100548
dc.identifier.pmid31517139
dc.type.categoryoriginal articleeng
dc.type.versionpublishedVersioneng
hcfmusp.author.externalABUCHAM-NETO, J.Z.:Medical Faculty of the ABC, Faculdade de Medicina do ABC, Av. Príncipe de Gales, 821, Santo André, SP, Brazil
hcfmusp.author.externalMASSON, A.P.:Medical Faculty of the ABC, Faculdade de Medicina do ABC, Av. Príncipe de Gales, 821, Santo André, SP, Brazil
hcfmusp.author.externalNASCIMENTO, P.A.:Medical Faculty of the ABC, Faculdade de Medicina do ABC, Av. Príncipe de Gales, 821, Santo André, SP, Brazil
hcfmusp.author.externalFERRAZ, A.A. Barbosa:Medical Faculty of the ABC, Faculdade de Medicina do ABC, Av. Príncipe de Gales, 821, Santo André, SP, Brazil
hcfmusp.description.articlenumber100548
hcfmusp.description.volume16
hcfmusp.origemSCOPUS
hcfmusp.origem.id2-s2.0-85071889364
hcfmusp.relation.referenceChao, D.L., Marsiglia, M., Ahmad, B., Peripapillary serous detachment in multiple evanescent white dot syndrome (2015) Retina, 35 (3), pp. 521-524eng
hcfmusp.relation.referenceNeves, A., Cardoso, A., Almeida, M., Unilateral Vogt-Koyanagi-Harada disease: a clinical case report (2015) Case Rep Ophthalmol, 6 (3), pp. 361-365eng
hcfmusp.relation.referenceFar, N.Y., Liu, D.T., Probable Vogt-Koyanagi-Harada disease with initial unilateral ocular manifestation in a hepatitis C carrier (2012) J Ophthalmic Inflamm Infect, 2 (4), pp. 235-237eng
hcfmusp.relation.referenceRead, R.W., Holland, G.N., Rao, N.A., Revised diagnostic criteria for Vogt-Koyanagi-Harada disease: report of an international committee on nomenclature (2001) Am J Ophthalmol, 131 (5), pp. 647-652eng
dc.description.indexPubMedeng
hcfmusp.citation.scopus0-
hcfmusp.scopus.lastupdate2022-04-29-
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