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https://observatorio.fm.usp.br/handle/OPI/35841
Title: | Diaphragm muscle structure in the elderly: Findings from an autopsy study |
Authors: | NUCCI, Ricardo Aparecido Baptista; SOUZA, Romeu Rodrigues de; SUEMOTO, Claudia Kimie; BUSSE, Alexandre Leopold; MAIFRINO, Laura Beatriz Mesiano; ANARUMA, Carlos Alberto; PASQUALUCCI, Carlos Augusto; JACOB-FILHO, Wilson |
Citation: | ACTA HISTOCHEMICA, v.122, n.2, article ID UNSP 151487, 5p, 2020 |
Abstract: | Sarcopenia is characterized as aging-related weakness and atrophy, which decreases the diaphragm force generating capacity leading to a decrease of expulsive non-ventilatory motor behaviors, which are critical for airway clearance. Thus, this study aimed to analyze the histopathology of the diaphragm in postmortem samples. Thirty individuals were included. Diaphragm samples were stained with hematoxylin and eosin for histopathological analysis. Picrosirius stain was used to highlight the collagen fibers. We observed a positive association between advancing age and histopathological findings in the diaphragm structure. We suggest that age is a key factor in increasing diaphragm muscle histopathology. However, further clinicopathological studies are needed to confirm our findings. |
Appears in Collections: | Artigos e Materiais de Revistas Científicas - FM/MCM Artigos e Materiais de Revistas Científicas - FM/MPT Artigos e Materiais de Revistas Científicas - HC/ICHC Artigos e Materiais de Revistas Científicas - LIM/22 Artigos e Materiais de Revistas Científicas - LIM/66 |
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art_NUCCI_Diaphragm_muscle_structure_in_the_elderly_Findings_from_2020.PDF.pdf Restricted Access | publishedVersion (English) | 1.61 MB | Adobe PDF | View/Open Request a copy |
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