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Title: Diaphragm muscle structure in the elderly: Findings from an autopsy study
Authors: NUCCI, Ricardo Aparecido BaptistaSOUZA, Romeu Rodrigues deSUEMOTO, Claudia KimieBUSSE, Alexandre LeopoldMAIFRINO, Laura Beatriz MesianoANARUMA, Carlos AlbertoPASQUALUCCI, Carlos AugustoJACOB-FILHO, Wilson
Citation: ACTA HISTOCHEMICA, v.122, n.2, article ID UNSP 151487, 5p, 2020
Abstract: Sarcopenia is characterized as aging-related weakness and atrophy, which decreases the diaphragm force generating capacity leading to a decrease of expulsive non-ventilatory motor behaviors, which are critical for airway clearance. Thus, this study aimed to analyze the histopathology of the diaphragm in postmortem samples. Thirty individuals were included. Diaphragm samples were stained with hematoxylin and eosin for histopathological analysis. Picrosirius stain was used to highlight the collagen fibers. We observed a positive association between advancing age and histopathological findings in the diaphragm structure. We suggest that age is a key factor in increasing diaphragm muscle histopathology. However, further clinicopathological studies are needed to confirm our findings.
Appears in Collections:Artigos e Materiais de Revistas Científicas - FM/MCM
Artigos e Materiais de Revistas Científicas - FM/MPT
Artigos e Materiais de Revistas Científicas - HC/ICHC
Artigos e Materiais de Revistas Científicas - LIM/22
Artigos e Materiais de Revistas Científicas - LIM/66

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