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Title: Genomic evidence of yellow fever virus in Aedes scapularis, southeastern Brazil, 2016
Authors: CUNHA, Mariana SequetinFARIA, Nuno RodriguesCALEIRO, Giovana SantosCANDIDO, Darlan SilvaHILL, Sarah C.CLARO, Ingra MoralesCOSTA, Antonio Charlys daNOGUEIRA, Juliana SilvaMAEDA, Adriana YurikaSILVA, Fernanda Gisele daSOUZA, Renato Pereira deSPINOLA, RobertaTUBAKI, Rosa MariaMENEZES, Regiane Maria Tironi deABADE, LeandroMUCCI, Luis FilipeTIMENETSKY, Maria do Carmo Sampaio TavaresSABINO, Esther
Citation: ACTA TROPICA, v.205, article ID UNSP 105390, 3p, 2020
Abstract: The southeastern region of Brazil has recently experienced the largest yellow fever disease outbreak in decades. Since July 2016 epizootic events were reported in Sao Paulo state's north region, where 787 Culicidae were captured as part of public health surveillance efforts and tested using real-time quantitative PCR. One Aedes scapularis pool collected in November 2016 in an agriculture area in Urupes city tested positive for YFV-RNA. Using a validated multiplex PCR approach we were able to recover a complete virus genome sequence from this pool. Phylogenetic analysis of the novel strain and publicly available data indicates that the belongs to the South American genotype 1 clade circulating in Sao Paulo state and is basal to the recent outbreak clade in southeast Brazil. Our findings highlight the need of additional studies, including vector competence studies, to disentangle the role of Aedes scapularis in yellow fever transmission in the Americas.
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Artigos e Materiais de Revistas Científicas - FM/MIP
Departamento de Moléstias Infecciosas e Parasitárias - FM/MIP

Artigos e Materiais de Revistas Científicas - IMT
Instituto de Medicina Tropical - IMT

Artigos e Materiais de Revistas Científicas - LIM/46
LIM/46 - Laboratório de Parasitologia Médica

Artigos e Materiais de Revistas Científicas - LIM/52
LIM/52 - Laboratório de Virologia

Artigos e Materiais de Revistas Científicas - ODS/03

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