LIM/01 - Laboratório de Informática Médica
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Prevalence of Serological and Molecular Markers of Hepatitis B Virus in Patients with Suspected Acute Hepatitis in Brazilian Health Services
JOURNAL OF MOLECULAR DIAGNOSTICS, v.25, n.11, suppl.S, p.S57-S57, 2023
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Toxoplasma gondii and Neospora caninum antibody seroprevalence and risk factors among dogs treated at Public Veterinary Hospitals in São Paulo, Brazil
REVISTA BRASILEIRA DE PARASITOLOGIA VETERINARIA, v.32, n.4, article ID e008723, 11p, 2023
Dogs can be infected by Toxoplasma gondii and Neospora caninum, for which they function, respectively, as intermediate, and definitive hosts. In the present study seroprevalence against T. gondii and N. caninum antibodies, were determined by indirect fluorescent antibody test (cut off of 16 and 5...
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Core Promoter and Pre-Core Variants of the Hepatitis B Virus (HBV) Are Frequent in Chronic Hepatitis B HBeAg-Negative Patients Infected by Genotypes A and D
VIRUSES-BASEL, v.15, n.12, article ID 2339, 11p, 2023
In Brazil, hepatitis B virus endemicity is low, moderate, or high in some areas, such as Espirito Santo State in the southeast region. In this study, we intend to characterize the basal core promoter (BCP) and pre-core region (PC) variants and their association with clinical/epidemiological disea...
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Seroprevalence of Zika in Brazil stratified by age and geographic distribution
EPIDEMIOLOGY AND INFECTION, v.151, article ID e197, 7p, 2023
Congenital Zika is a devastating consequence of maternal Zika virus infections. Estimates of age-dependent seroprevalence profiles are central to our understanding of the force of Zika virus infections. We set out to calculate the age-dependent seroprevalence of Zika virus infections in Brazil. W...
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Better to be in agreement than in bad company A critical analysis of many kappa-like tests
BEHAVIOR RESEARCH METHODS, v.55, n.7, p.3326-3347, 2023
We assessed several agreement coefficients applied in 2x2 contingency tables, which are commonly applied in research due to dichotomization. Here, we not only studied some specific estimators but also developed a general method for the study of any estimator candidate to be an agreement measureme...
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Risk of malaria for travelers with stable malaria transmission
Massad, E.; Behrens, R. H.; Burattini, M. N.; Coutinho, F. A. B.. Risk of malaria for travelers with stable malaria transmission. In: . Hospitality and Health: Issues and Developments: APPLE ACADEMIC PRESS, 2011. p.9-16.
A mathematical model was developed to estimate the risk of non-immune individual acquiring falciparum malaria when traveling to the Amazon region of Brazil. The risk of malaria infection to travelers was calculated as a function of duration of exposure and season of arrival. © 2012 by Apple Acade...
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Cost-effectiveness analysis of diagnostics tests of respiratory tract infection in cancer patients
EUROPEAN RESPIRATORY JOURNAL, v.48, suppl.60, 2016
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Chronic exposure to cigarette smoke transiently worsens the disease course in a mouse model of pulmonary paracoccidioidomycosis
REVISTA DO INSTITUTO DE MEDICINA TROPICAL DE SãO PAULO, v.64, p.e71, 2022
ABSTRACT Paracoccidioidomycosis (PCM) may present as an acute/subacute clinical form, characterized by a progressive disease arising from the airborne initial infection, or, most often, as an asymptomatic or subclinical infection that may manifest later during an individual’s life, the chronic fo...
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Time-dependent vaccine efficacy estimation quantified by a mathematical model
PLOS ONE, v.18, n.5, article ID e0285466, 18p, 2023
In this paper we calculate the variation of the estimated vaccine efficacy (VE) due to the time-dependent force of infection resulting from the difference between the moment the Clinical Trial (CT) begins and the peak in the outbreak intensity. Using a simple mathematical model we tested the hypo...
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Effects of migration rates and vaccination on the spread of yellow fever in Latin American communities
REVISTA PANAMERICANA DE SALUD PUBLICA-PAN AMERICAN JOURNAL OF PUBLIC HEALTH, v.47, article ID e86, 10p, 2023
Objective. To assess how relevant the flow of people between communities is, compared to vaccination and type of vector, on the spread and potential outbreaks of yellow fever in a disease-free host community.Methods. Using a SEIRV-SEI model for humans and vectors, we applied numerical simulations...
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