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1. Itraconazole Serum Trough Concentrations Using Oral Capsules for the Treatment of Chronic Pulmonary Aspergillosis: What is the Target?

   MYCOPATHOLOGIA, v.188, n.5, Special Issue, p.693-698, 2023

   BackgroundIn regions where there is only itraconazole capsule as a therapeutic option for treatment of chronic pulmonary aspergillosis (CPA), measuring the serum concentrations becomes even more important for therapeutic success.ObjectiveEvaluate the initial itraconazole serum trough concentratio...

2. Evaluation of enterovirus concentration, species identification, and cerebrospinal fluid parameters in patients of different ages with aseptic meningitis in Sao Paulo, Brazil

   JOURNAL OF MEDICAL VIROLOGY, v.96, n.2, article ID e29471, 8p, 2024

   Human enteroviruses (EV) are the most common cause of aseptic meningitis worldwide. Data on EV viral load in cerebrospinal fluid (CSF) and related epidemiological studies are scarce in Brazil. This study investigated the influence of EV viral load on CSF parameters, as well as identifying the inv...

3. Clinical and epidemiological features of mpox in a Brazilian reference center for HIV and sexually transmitted infections: A cross-sectional study

   IJID REGIONS, v.10, p.114-122, 2024

   Background: The 2022 mpox outbreak has affected disproportionately people living with HIV (PLWH) and pre-exposure prophylaxis (PrEP) users. Methods: We conducted a cross-sectional study to evaluate factors associated with laboratory diagnosis of mpox among suspected cases, and access differences ...

4. Serosurvey of <i>Toxoplasma gondii</i> and <i>Toxocara</i> spp. co-infection in pregnant women in low-income areas of Brazil

   FRONTIERS IN PUBLIC HEALTH, v.12, article ID 1340434, 9p, 2024

   Introduction: Despite human toxoplasmosis and toxocariasis having been listed among the top six most neglected parasitic zoonoses worldwide, presenting similar associated risk factors and transmission routes, few studies have been conducted in pregnant women and the consequences of concurrent inf...

5. The decline of measles antibody titers in previously vaccinated adults: a cross-sectional analysis

   REVISTA DO INSTITUTO DE MEDICINA TROPICAL DE SAO PAULO, v.66, article ID e4, 10p, 2024

   The global reemergence of measles in 2018-2019 reinforces the relevance of high coverage immunization to maintain the disease elimination. During an outbreak in the Sao Paulo State in 2019, several measles cases were reported in individuals who were adequately vaccinated according to the current ...

6. Epidemiology, treatment patterns, and disease burden of cytomegalovirus in hematopoietic cell transplant recipients in selected countries outside of Europe and North America: A systematic review

   TRANSPLANT INFECTIOUS DISEASE, v.25, n.4, 2023

   Background: Cytomegalovirus (CMV) disease impacts morbidity and mortality in hematopoietic cell transplant (HCT) recipients. This systematic review summarized data on the epidemiology, management, and burden of CMV post-HCT outside of Europe and North America.Methods: The MEDLINE, Embase, and Coc...

7. Hydroxymethylnitrofurazone lymphatic uptake with nanostructured lipid carrier after oral administration in rats

   NANOMEDICINE, v.19, n.4, p.293-301, 2024

   Background: Leishmaniasis, caused by the protozoan Leishmania sp., infects phagocyte cells present in lymphatic organs. This study demonstrates the influence of nanostructured lipid carrier-loaded hydroxymethylnitrofurazone (NLC-NFOH) on lymphatic uptake using a chylomicron-blocking flow model in...

8. Global prevalence, cascade of care, and prophylaxis coverage of hepatitis B in 2022: a modelling study

   LANCET GASTROENTEROLOGY & HEPATOLOGY, v.8, n.10, p.879-907, 2023

   Background The 2016 World Health Assembly endorsed the elimination of hepatitis B virus (HBV) infection as a public health threat by 2030; existing therapies and prophylaxis measures make such elimination feasible, even in the absence of a virological cure. We aimed to estimate the national, regi...

9. Quantitative PCR as a marker for preemptive therapy and its role in therapeutic control in <i>Trypanosoma cruzi</i>/HIV coinfection

   PLOS NEGLECTED TROPICAL DISEASES, v.18, n.2, article ID e0011961, 24p, 2024

   Background Trypanosoma cruzi and HIV coinfection can evolve with depression of cellular immunity and increased parasitemia. We applied quantitative PCR (qPCR) as a marker for preemptive antiparasitic treatment to avoid fatal Chagas disease reactivation and analyzed the outcome of treated cases. M...

10. Clinical characteristics, diagnosis, and treatment of central nervous system sporotrichosis: Systematic review and meta-analysis

    MYCOSES, v.67, n.2, article ID e13697, 8p, 2024

    BackgroundThe clinical features of central nervous system (CNS) sporotrichosis are derived from case reports and a limited series of cases. Our objective was to carry out a systematic review and meta-analysis of CNS sporotrichosis.MethodsWe searched PubMed/MEDLINE, Embase, Scopus, and LILACS on 9...