LIM/03 - Laboratório de Medicina Laboratorial

O Laboratório de Medicina Laboratorial é ligado ao Departamento de Patologia da Faculdade de Medicina da Universidade de São Paulo (FMUSP).

Linhas de pesquisa: epidemiologia; morfometria; defesa respiratória; poluição em plantas; patologia pulmonar e mutagênese ambiental.

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Recent Submissions

  1. 2021 recommendations of the Brazilian Society of Rheumatology for the gynecological and obstetric care of patients with Sjogren's syndrome (vol 61, 54, 2021)

    ADVANCES IN RHEUMATOLOGY, v.62, n.1, article ID 8, 2p, 2022

  2. Cytogenomics Investigation of Infants with Congenital Heart Disease: Experience of a Brazilian Center

    ARQUIVOS BRASILEIROS DE CARDIOLOGIA, v.118, n.1, p.61-67, 2022

    Background: Some syndromes have specific and easily recognizable features, while others may be more complex to identify and may present different phenotypic manifestations, for example. An etiological diagnosis is important to understand the nature of the disease, to establish the prognosis and t...

  3. A Brazilian Inter-Hospital Candidemia Outbreak Caused by Fluconazole-Resistant Candida parapsilosis in the COVID-19 Era

    JOURNAL OF FUNGI, v.8, n.2, article ID 100, 8p, 2022

    Horizontal transmission of fluconazole-resistant Candida parapsilosis (FRCP) through healthcare workers' hands has contributed to the occurrence of candidemia outbreaks worldwide. Since the first COVID-19 case in Brazil was detected in early 2020, hospitals have reinforced hand hygiene and disinf...

  4. Effect of a single high dose of vitamin D-3 on cytokines, chemokines, and growth factor in patients with moderate to severe COVID-19

    AMERICAN JOURNAL OF CLINICAL NUTRITION, v.115, n.3, p.790-798, 2022

    Background: The modulating effect of vitamin D on cytokine concentrations in severe coronavirus disease 2019 (COVID-19) remains unknown. Objectives: We aimed to investigate the effect of a single high dose of vitamin D-3 on cytokincs, chemokines, and growth factor in hospitalized patients with mo...

  5. COVID-19 bimodal clinical and pathological phenotypes

    CLINICAL AND TRANSLATIONAL MEDICINE, v.12, n.1, article ID e648, 6p, 2022

  6. A more gradual positive end-expiratory pressure increase reduces lung damage and improves cardiac function in experimental acute respiratory distress syndrome

    JOURNAL OF APPLIED PHYSIOLOGY, v.132, n.2, p.375-387, 2022

    Increases in positive end-expiratory pressure (PEEP) or recruitment maneuvers may increase stress in lung parenchyma, extracellular matrix, and lung vessels; however, adaptative responses may occur. We evaluated the effects of PEEP on lung damage and cardiac function when increased abruptly, grad...

  7. Effects of time-controlled adaptive ventilation on cardiorespiratory parameters and inflammatory response in experimental emphysema

    JOURNAL OF APPLIED PHYSIOLOGY, v.132, n.2, p.564-574, 2022

    The time-controlled adaptive ventilation (TCAV) method attenuates lung damage in acute respiratory distress syndrome. However, so far, no study has evaluated the impact of the TCAV method on ventilator-induced lung injury (VILI) and cardiac function in emphysema. We hypothesized that the use of t...

  8. Monitoring non-small cell lung cancer progression and treatment response through hyaluronic acid in sputum

    BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH, v.55, n.1, article ID e11513, 9p, 2022

    We evaluated whether hyaluronan (HA) levels in the sputum could be used as a noninvasive tool to predict progressive disease and treatment response, as detected in a computed tomography scan in non-small cell lung cancer (NSCLC) patients. Sputum samples were collected from 84 patients with histol...

  9. Vertebral segmentation defects in a Brazilian cohort: Clinical and molecular analysis focused on spondylocostal dysostosis

    CLINICAL GENETICS, v.101, n.4, p.476-478, 2022

  10. Impact of Three Methods of Ischemic Preconditioning on Ischemia-Reperfusion Injury in a Pig Model of Liver Transplantation

    JOURNAL OF INVESTIGATIVE SURGERY, v.35, n.4, p.900-909, 2022

    Background Ischemic preconditioning (IPC), either direct (DIPC) or remote (RIPC), is a procedure aimed at reducing the harmful effects of ischemia-reperfusion (I/R) injury. Objectives To assess the local and systemic effects of DIPC, RIPC, and both combined, in the pig liver transplant model. Mat...