LIM/13 - Laboratório de Genética e Cardiologia Molecular

O Laboratório de Genética e Cardiologia Molecular é ligado ao Departamento de Cardiopneumologia da Faculdade de Medicina da Universidade de São Paulo (FMUSP).

Linhas de pesquisa: identificação e caracterização de biomarcadores para utilização em algoritmos de apoio à decisão médica; desenvolvimento de estratégias para reparação de órgãos com baixa capacidade regenerativa; genética das doenças cardiovasculares; evolução das câmaras cardíacas; biologia do desenvolvimento do coração; cardiopatias congênitas; sinalização pelo ácido retinoico; desenvolvimento de vetores virais portadores de genes supressores de tumor e imunoestimuladores para terapia gênica do câncer.

Site oficial: http://limhc.fm.usp.br/portal/lim13-laboratorio-de-genetica-e-cardiologia-molecular/

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Recent Submissions

  1. Rivaroxaban versus warfarin in postoperative atrial fibrillation: Cost-effectiveness analysis in a single-center, randomized, and prospective trial

    JTCVS OPEN, v.15, p.199-210, 2023

    Objectives: Postoperative atrial fibrillation is the most common clinical complication after coronary artery bypass graft surgery. It is associated with a high risk of both stroke and death and increases the length of hospital stay and costs. This study aimed to evaluate anticoagulants in postope...

  2. Paradoxical Findings in Homozygous Familial Hypercholesterolemia in Japan: Longer Life But Still Not Totally Better!

    JACC: ASIA, v.3, n.6, p.892-894, 2023

  3. Long term outcome after septal reduction therapies in patients with hypertrophic cardiomyopathy: insights from the SHaRe registry

    EUROPEAN HEART JOURNAL, v.44, suppl.2, 2023

  4. Effectiveness and tolerability of trimetazidine 80mg once daily in patients with chronic coronary syndrome: the V-GOOD observational study

    EUROPEAN HEART JOURNAL, v.44, suppl.2, 2023

  5. Impact of Coronary Atherosclerotic Burden on the Long-Term Prognosis of Patients With Chronic Kidney Disease Undergoing Renal Replacement Therapy

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, v.82, n.17, suppl.S, p.B280-B280, 2023

  6. SITOSTEROLEMIA AND PREMATURE CORONARY ATHEROSCLEROSIS IN A YOUNG WOMAN: A CASE REPORT.

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, v.81, n.8, suppl.A, p.3433-3433, 2023

  7. GlycA, but Not C-reactive Protein is Associated With Baseline Carotid Artery Plaque in the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil)

    CIRCULATION, v.147, suppl.1, 2023

  8. Association of Lipoprotein Subfractions With Atherosclerosis in the Baseline Sample of ELSA-Brasil Cohort Study - A Cross-Sectional Analysis

    CIRCULATION, v.147, suppl.1, 2023

  9. Update on Sitosterolemia and Atherosclerosis

    CURRENT ATHEROSCLEROSIS REPORTS, v.25, n.5, p.181-187, 2023

    Purpose of ReviewThe purpose of this review was to summarize important and updated information on sitosterolemia. Sitosterolemia is an inherited lipid disorder consisting of high levels of plasma plant sterols. This sterol storage condition is caused by biallelic loss-of-function genetic variants...

  10. Effect of Low-Dose Progesterone on Glycemic Metabolism, Morphology and Function of Adipose Tissue and Pancreatic Islets in Diet-Induced Obese Female Mice

    FRONTIERS IN BIOSCIENCE-LANDMARK, v.28, n.11, article ID 312, 14p, 2023

    Background: Obesity is a worldwide concern due to its global rapid expansion and remarkable impact on individual's health by predisposing to several other diseases. About twice as many women as men suffer from severe obesity and, in fact, there are stages in a woman's life when weight gain and ad...