LIM/15 - Laboratório de Investigação em Neurologia

O Laboratório de Investigação em Neurologia é ligado ao Departamento de Neurologia da Faculdade de Medicina da Universidade de São Paulo (FMUSP).

Linhas de pesquisa: líquido cefalorraquiano; neuroinfecção; demências; biologia molecular e celular dos tumores do sistema nervoso central; miopatias; anticonvulsivantes; estresse oxidativo em distúrbios cognitivos e do comportamento; estimulação magnética transcraniana.

Site oficial: http://limhc.fm.usp.br/portal/lim15-laboratorio-de-investigacao-em-neurologia/

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Envíos recientes

  1. PATIENT AND CAREGIVER SPINAL MUSCULAR ATROPHY (SMA) TREATMENT ATTRIBUTE PREFERENCES IN LATIN AMERICA

    VALUE IN HEALTH, v.26, n.6, suppl.S, p.S239-S239, 2023

  2. LOXL3 knock out affects pathways which involve cytoskeleton regulation, proliferation and apoptosis in glioblastoma cells

    CANCER RESEARCH, v.83, n.7, suppl.S, 2023

  3. Hemifacial Spasm: gene expression and immunohistochemical analysis

    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, v.64, n.8, article ID 4081, 3p, 2023

  4. Metabolic and Structural Signatures in Corticobasal Syndrome: A Multimodal PET/MRI Study

    BIOPHYSICAL REVIEWS, v.13, n.6, Special Issue, p.1471-1471, 2021

  5. Epigenetic dedifferentiation as a therapeutic strategy in adrenal cancer

    CANCER RESEARCH, v.83, n.7, suppl.S, 2023

  6. Cerebral venous sinus thrombosis due to vaccine-induced immune thrombotic thrombocytopenia in middle-income countries

    INTERNATIONAL JOURNAL OF STROKE, v.18, n.9, p.1112-1120, 2023

    Background: Adenovirus-based COVID-19 vaccines are extensively used in low- and middle-income countries (LMICs). Remarkably, cases of cerebral venous sinus thrombosis due to vaccine-induced immune thrombotic thrombocytopenia (CVST-VITT) have rarely been reported from LMICs. Aims: We studied the f...

  7. Association between APOE-ε4 allele and cognitive function is mediated by Alzheimer's disease pathology: a population-based autopsy study in an admixed sample

    ACTA NEUROPATHOLOGICA COMMUNICATIONS, v.11, n.1, article ID 205, 10p, 2023

    Background: Apolipoprotein E epsilon 4 allele (APOE-epsilon 4) is the main genetic risk factor for late-onset Alzheimer's disease (AD) and may impact cognitive function also via other neuropathological lesions. However, there is limited evidence available from diverse populations, as APOE associa...

  8. Biomarkers for dementia in Latin American countries: Gaps and opportunities

    ALZHEIMERS & DEMENTIA, v.19, n.2, p.721-735, 2023

    Limited knowledge on dementia biomarkers in Latin American and Caribbean (LAC) countries remains a serious barrier. Here, we reported a survey to explore the ongoing work, needs, interests, potential barriers, and opportunities for future studies related to biomarkers. The results show that neuro...

  9. The past, present and future of Alzheimer's disease - part 1: the past

    ARQUIVOS DE NEURO-PSIQUIATRIA, v.81, n.12, p.1070-1076, 2023

    Background Alzheimer's disease (AD) was described in 1907, and since then it changed from a relatively rare condition to one of the most prevalent diseases.Objective To describe the evolution of the notions of dementias and AD, and to investigate the reasons for the increase in scientific interes...

  10. Measurement of resistance-area product by transcranial Doppler: An alternative tool for cognitive screening in hypertensive on drug treatment?

    CEREBRAL CIRCULATION-COGNITION AND BEHAVIOR, v.5, article ID 100191, 7p, 2023

    Introduction: Arterial hypertrophy and remodeling are adaptive responses present in systemic arterial hyper-tension that can result in silent ischemia and neurodegeneration, compromising brain connections and cognitive performance (CP). However, CP is affected differently over time, so traditiona...