LIM/16 - Laboratório de Fisiopatologia Renal
Linhas de pesquisa: hipertensão experimental: cloreto de sódio; nefropatias progressivas e doença óssea metabólica (osteodistrofia renal, osteoporose).
Site oficial: http://limhc.fm.usp.br/portal/lim16-laboratorio-de-fisiopatologia-renal/
Collections in this community
Hepatocyte Nuclear Factor 4 alpha is a novel osteoblast transcription factor that regulates osteogenesis and plays a role in ROD pathogenesis
JOURNAL OF BONE AND MINERAL RESEARCH, v.38, suppl.1, p.4-4, 2023
Effect of aluminum accumulation on bone and cardiovascular risk in the current era
PLOS ONE, v.18, n.4, 2023
BackgroundThe prevalence of aluminum (Al) intoxication has declined over the past 3 decades. However, different groups still report on the diagnosis of Al in bone. Prolonged and low-intensity exposures to Al may not be captured by serum Al measurements, preventing its proper diagnosis. We hypothe...
Overview of renal osteodystrophy in Brazil: a cross-sectional study
JORNAL BRASILEIRO DE NEFROLOGIA, v.45, n.2, p.257-261, 2023
Introduction: The epidemiologic profile of renal osteodystrophy (ROD) is changing over time and cross-sectional studies provide essential information to improve care and health policies. The Brazilian Registry of Bone Biopsy (REBRABO) is a prospective, nationalmulticenter cohort that includes pat...
International Perspectives on GFR Estimation and Race-Based Adjustments
CLINICAL CHEMISTRY, v.69, n.8, p.796-802, 2023
Chronic environmental hypoxia attenuates innate immunity activation and renal injury in two CKD models
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, v.325, n.3, p.F283-F298, 2023
Tissue hypoxia has been pointed out as a major pathogenic factor in chronic kidney disease (CKD). However, epidemiological and experimental evidence inconsistent with this notion has been described. We have previously reported that chronic exposure to low ambient Po-2 promoted no renal injury in ...
Bevacizumab-Associated Thrombotic Microangiopathy Treated with Eculizumab: A Case Report
AMERICAN JOURNAL OF CASE REPORTS, v.24, article ID e940906, 7p, 2023
Patient: Female, 64-year-old Final Diagnosis: Bevacizumab-associated thrombotic microangiopathy Symptoms: Microangiopathic hemolytic anemia and acute kidney injury Clinical Procedure: - Specialty: Nephrology Objective: Rare disease Background: Bevacizumab is an approved targeted therapy for metas...
A Prospective Cross-Sectional Study on the Performance of the 2021 CKD-EPI Equations Without Race in a Multiracial Population of Adults With Solid Tumors in Brazil
AMERICAN JOURNAL OF KIDNEY DISEASES, v.82, n.2, p.247-249, 2023
In memoriam: Professor Gerhard Malnic
JORNAL BRASILEIRO DE NEFROLOGIA, v.45, n.2, p.266-268, 2023
Doença renal crônica
Silva, Bruno Caldin da; Elias, Rosilene Motta. Doença renal crônica. In: Favarato, Maria Helena Sampaio; Saad, Rafael; Ivanovic, Lígia Fidelis; Jorge, Maria Cecília Pavanel; Oliveira, Júlio César de; Santos, Valter Garcia; Morinaga, Christian Valle; Bricola, Solange Aparecida Petilo de Carvalho; Nunes, Maria do Patrocínio Tenório; Martins, Mílton de Arruda (eds); Soeiro, Alexandre de Matos; Silva, Bruno Caldin da; Filadelfo, Cesar Ribeiro; Andrade, Daniel Ciampi de; Carvalho, Daniel Fiordelisio de; Nakagawa, Daniel Makoto; Sitnik, Debora; Colombo, Elisabetta Sachsida; Fonseca, Fabricio Lopes da; Lauterbach, Gerhard da Paz; Maesaka, Jonathan Yugo; Oliveira, Júlio César de; Ivanovic, Lígia Fidelis; Fonseca, Luciana Mazoti Lopes da; Gil Junior, Luiz Antonio; Marzinotto, Maira Andrade Nacimbem; Aun, Marcelo Vivolo; Vieira, Marcio Eduardo Bergamini; Jorge, Maria Cecília Pavanel; Nunes, Maria do Patrocínio Tenório; Favarato, Maria Helena Sampaio; D´Alessandro, Maria Perez Soares; Cordeiro, Maurício Dener; Mak, Milena Perez; Lima, Moisés da Cunha; Guidi, Paula Machado; Saad, Rafael; Teixeira, Ralcyon Francis Azevedo; Bricola, Solange Aparecida Petilo de Carvalho; Takahashi, Tiago Kenji; Santos, Valter Garcia; Cesar, Wagner G. Galvão; Nahas, William (coords). Manual do residente de clínica médica [3.ed.]. SANTANA DE PARNAÍBA: Manole, 2023. p.649-657.
Transcription factor HNF4 & alpha;2 promotes osteogenesis and prevents bone abnormalities in mice with renal osteodystrophy
JOURNAL OF CLINICAL INVESTIGATION, v.133, n.11, article ID e159928, 18p, 2023
Renal osteodystrophy (ROD) is a disorder of bone metabolism that affects virtually all patients with chronic kidney disease (CKD) and is associated with adverse clinical outcomes including fractures, cardiovascular events, and death. In this study, we showed that hepatocyte nuclear factor 4 & alp...