LIM/17 - Laboratório de Investigação em Reumatologia

LIM/17 - Laboratório de Investigação em Reumatologia

 

O Laboratório de Investigação em Reumatologia é ligado ao Departamento de Clínica Médica da Faculdade de Medicina da Universidade de São Paulo (FMUSP).

Linhas de pesquisa: autoimunidade e doenças reumatológicas; clínica, diagnóstico, coinfecção e tratamento da doença de Lyme no Brasil; matriz extracelular nas doenças difusas do tecido conjuntivo; modelo experimental de artrose e esclerodermia; fisiopatologia da resposta inflamatória; terapêutica nas artrites inflamatórias crônicas; osteoporose e doenças reumatológicas; biologia molecular e celular aplicada a doenças osteometabólicas; LES, vasculites e doença de Takayasu; medicina esportiva, coluna e doenças reumatológicas.

Site oficial:Site oficial: http://www.limhc.fm.usp.br/portal/lim17-laboratorio-de-investigacao-em-reumatologia/

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  • ZHANG, Hui; DANTAS, Wagner; KING, William T.; AXELROD, Christopher L.; GIL, Saulo; MURAI, Igor; ROSCHEL, Hamilton; GUALANO, Bruno; KIRWAN, John P. (AMER DIABETES ASSOC, ALEXANDRIA, USA, 2019)
  • SILVEIRA, Lizandre Keren; RODRIGUES, Jose Eduardo; ATAYDE, Silvana; CATANOZI, Sergio; SANTOS FILHO, Antonio dos; CAPELOZZI, Vera Luiza; FULLER, Ricardo; VELOSA, Ana Paula; TEODORO, Walcy (WILEY, HOBOKEN, USA, 2019)
  • KILTZ, Uta; LANDEWE, Robert B. M.; HEIJDE, Desiree van der; RUDWALEIT, Martin; WEISMAN, Michael H.; AKKOC, Nurullah; BOONEN, Annelies; BRANDT, Jan; CARRON, Philippe; DOUGADOS, Maxime; GOSSEC, Laure; JONGKEES, Merryn; MACHADO, Pedro M.; MARZO-ORTEGA, Helena; MOLTO, Anna; NAVARRO-COMPAN, Victoria; NIEDERMAN, Karin; SAMPAIO-BARROS, Percival Degrava; SLOBODIN, Gleb; BOSCH, Filip E. van den; TUBERGEN, Astrid van; WEELY, Salima van; WIEK, Dieter; BRAUN, Juergen (BMJ PUBLISHING GROUP, LONDON, ENGLAND, 2020)
    Objectives The Assessment of SpondyloArthritis International Society (ASAS) aimed to develop a set of quality standards (QS) to help improve the quality of healthcare provided to adult patients affected by axial spondyloarthritis ...
  • ASSAD, Ana Paula Luppino; FARIAS, Rebeca; GASPARI, Camila N.; SILVA, Henrique Carrico da; ANDRADE, Danieli Castro O.; SAMPAIO-BARROS, Percival D. (LIPPINCOTT WILLIAMS & WILKINS, PHILADELPHIA, USA, 2020)
  • MEIRELES, Kamila; PECANHA, Tiago; DIAS, Andre R. L.; SOUZA, Katrice A.; ARAUJO, Jaqueline A.; SILVA, Juliana S.; REZENDE, Diego A. N.; SANTOS, Roberto J.; CAMBRI, Lucieli T.; ARSA, Gisela (LIPPINCOTT WILLIAMS & WILKINS, PHILADELPHIA, USA, 2020)
    Objective: To investigate the effects of a single session of moderate-intensity and high-intensity interval exercise in cardiovascular reactivity to the cold pressor test in young adults with excess body weight. Methods: ...
  • RIBEIRO, Rafael; DUARTE, Breno; SILVA, Andre Guedes da; RAMOS, Guilherme Passos; PICANCO, Andreia Rossi; PENNA, Eduardo Macedo; COSWIG, Victor; BARBALHO, Matheus; GENTIL, Paulo; GUALANO, Bruno; SAUNDERS, Bryan (FRONTIERS MEDIA SA, LAUSANNE, SWITZERLAND, 2020)
    Purpose: High-intensity activity is an important aspect of football performance during competitive match play. The aim of this study was to investigate the effect of beta-alanine supplementation throughout a short-duration ...
  • TUSTUMI, Francisco; TAKEDA, Flavio Roberto; VIYUELA, Mateus Silva; CRUZ JUNIOR, Jurandir Batista da; BRANDAO, Antonio Adolfo Guerra Soares; SALLUM, Rubens Antonio Aissar; RIBEIRO JUNIOR, Ulysses; CECCONELLO, Ivan (WILEY, HOBOKEN, USA, 2020)
    Background Inflammation status plays an important role in the natural history of malignancy. Consequently, hematological markers of systemic inflammation may predict prognosis in neoplasms. This study evaluated the value ...
  • SEGURO, Luis F. B. C.; PEREIRA, Rosa M. R.; SEGURO, Luciana P. C.; CAPARBO, Valeria F.; AVILA, Monica S.; MANGINI, Sandrigo; CAMPOS, Iascara W.; GAIOTTO, Fabio A.; MARCONDES-BRAGA, Fabiana G.; BACAL, Fernando (LIPPINCOTT WILLIAMS & WILKINS, PHILADELPHIA, USA, 2020)
    Background. Data on the prevention of fractures after heart transplant (HTx) are controversial in the literature. Understanding the effects of HTx on bone may guide appropriate treatments in this high-risk population. ...
  • FONSECA, G. W. P. D.; SANTOS, Marcelo Rodrigues dos; SOUZA, Francis Ribeiro de; TAKAYAMA, Liliam; PEREIRA, Rosa Maria Rodrigues; NEGRAO, Carlos Eduardo; ALVES, Maria-Janieire de Nazare Nunes (WILEY PERIODICALS, INC, SAN FRANCISCO, USA, 2020)
    Aims The definition of sarcopenia based on appendicular lean mass/height ((2)) (ALM/height ((2))) is often used, although it can underestimate the prevalence of sarcopenia in overweight/obese patients with heart failure. ...
  • PONS-ESTEL, Guillermo J.; UGARTE-GIL, Manuel Francisco; HARVEY, Guillermina B.; WOJDYLA, Daniel; QUINTANA, Rosana; SAURIT, Veronica; SORIANO, Enrique R.; BONFA, Eloisa; MASSARDO, Loreto; CARDIEL, Mario; VILA, Luis M.; GRIFFIN, Russell; PONS-ESTEL, Bernardo A.; ALARCON, Graciela S. (BMJ PUBLISHING GROUP, LONDON, ENGLAND, 2020)
    Objective To evaluate the performance of the 2019 European League Against Rheumatism (EULAR)/American College of Rheumatology (ACR) systemic lupus erythematosus (SLE) criteria in terms of earlier patients' classification ...
  • SMAIRA, Fabiana Infante; MAZZOLANI, Bruna Caruso; PECANHA, Tiago; SANTOS, Kamila Meireles dos; REZENDE, Diego Augusto Nunes; ARAUJO, Maria Eugenia; BONFIGLIOLI, Karina; SCAGLIUSI, Fernanda Baeza; BENATTI, Fabiana Braga; PINTO, Ana Lucia de Sa; LIMA, Fernanda Rodrigues; PEREIRA, Rosa Maria R.; ROSCHEL, Hamilton; GUALANO, Bruno; PINTO, Ana Jessica (SPRINGER LONDON LTD, LONDON, ENGLAND, 2020)
    To investigate the association between food consumption stratified by processing level and cardiovascular risk factors in rheumatoid arthritis. In this cross-sectional study, 56 patients (age: 62.5 +/- 7.9 years, BMI: 28.4 ...
  • CRUVINEL, Wilson de Melo; ANDRADE, Luis Eduardo Coelho; MUHLEN, Carlos Alberto von; DELLAVANCE, Alessandra; XIMENES, Antonio Carlos; BICHARA, Carlos David; BUENO, Cleonice; MANGUEIRA, Cristovao Luis Pitangueira; BONFA, Eloisa; BRITO, Fabiano de Almeida; FLUMIAN, Fernanda Bull; SILVA, Glaucielen Gomes da; REGO, Jozelia; ANJOS, Lisiane Maria Ericoni dos; SLHESSARENKO, Natasha; PASOTO, Sandra Gofinet; NEVES, Suzane Pretti Figueiredo; VALIM, Valeria; SANTOS, Wilton Silva dos; FRANCESCANTONIO, Paulo Luiz Carvalho (BMC, LONDON, ENGLAND, 2020)
    After publication of the original article [1], we were notified that there is a mistake in Fig. 2.
  • ROSA NETO, Nilton Salles; BENTO, Judith Campos de Barros; PEREIRA, Rosa Maria Rodrigues (BMC, LONDON, ENGLAND, 2020)
    Background Fabry disease (FD) is an X-linked lysosomal disorder due to mutations in the GLA gene resulting in defective enzyme alpha-galactosidase A. FD patients are frequently misdiagnosed, commonly for rheumatic diseases. ...
  • ROSA NETO, Nilton Salles; BENTO, Judith Campos de Barros; PEREIRA, Rosa Maria Rodrigues (ELSEVIER, AMSTERDAM, NETHERLANDS, 2020)
    Background: Fabry disease (FD) is a lysosomal disease in which mutations affect the GLA gene located on the X chromosome. The defective product, the enzyme alpha-galactosidase A, causes accumulation of substrate and ...
  • PEDROSA, Tatiana N.; PASOTO, Sandra G.; AIKAWA, Nadia E.; YUKI, Emily F. N.; BORBA, Eduardo F.; FERREIRA FILHO, Julio C. R.; CARRICONDO, Pedro C.; ZANETTI, Caio B.; CONDE, Paola G.; DUARTE, Nilo J. C.; FONTOURA, Nicole; ROMANO, Paschoalina; CARVALHO, Valdemir M.; SILVA, Clovis A.; BONFA, Eloisa (SAGE PUBLICATIONS LTD, LONDON, ENGLAND, 2020)
    Objectives It is unknown if hydroxychloroquine blood level dynamics impact flare rates in lupus nephritis patients. We prospectively evaluated hydroxychloroquine levels to determine which blood-based patterns are more ...
  • SHINJO, Samuel Katsuyuki; SOUZA, Fernando Henrique Carlos de (TAYLOR & FRANCIS LTD, ABINGDON, ENGLAND, 2020)
    Introduction: Current literature has minimal solid data to guide therapeutic intervention in adult dermatomyositis and studies that include systemic inflammatory mechanism suppression, musculoskeletal and extra-muscular ...
  • LOBO, Alexandre R.; GAIEVSKI, Eduardo H. S.; MESQUITA, Carlos Henrique de; CARLI, Eduardo De; TEIXEIRA, Pryscila Dryelle S.; PEREIRA, Rosa M. R.; BORELLI, Primavera; SA, Lilian R. M. de; COLLI, Celia (CAMBRIDGE UNIV PRESS, CAMBRIDGE, ENGLAND, 2020)
    The present study reports the effects of a high-fat (HF) diet of over 8 weeks on the Fe status of growing rats. Tissue Fe levels were analysed by atomic absorption spectrophotometry, and whole-body adiposity was measured ...
  • DOLAN, Eimear; VARLEY, Ian; ACKERMAN, Kathryn E.; PEREIRA, Rosa Maria R.; ELLIOTT-SALE, Kirsty Jayne; SALE, Craig (LIPPINCOTT WILLIAMS & WILKINS, PHILADELPHIA, USA, 2020)
    Bone (re)modeling markers can help determine how the bone responds to different types, intensities, and durations of exercise. They also might help predict those at risk of bone injury. We synthesized evidence on the acute ...
  • GONCALVES, Livia de Souza; KRATZ, Caroline; SANTOS, Livia; CARVALHO, Victor Henrique; SALES, Lucas Peixoto; NEMEZIO, Kleiner; LONGOBARDI, Igor; RIANI, Luiz Augusto; LIMA, Marcelo Miranda de Oliveira; SAITO, Tiemi; FERNANDES, Alan Lins; RODRIGUES, Joice; JAMES, Ruth Margaret; SALE, Craig; GUALANO, Bruno; GELONEZE, Bruno; MEDEIROS, Marisa Helena Gennari de; ARTIOLI, Guilherme Giannini (AMER PHYSIOLOGICAL SOC, BETHESDA, USA, 2020)
    To test whether high circulating insulin concentrations influence the transport of beta-alanine into skeletal muscle at either saturating or subsaturating beta-alanine concentrations, we conducted two experiments whereby ...

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