LIM/23 - Laboratório de Psicopatologia e Terapêutica Psiquiátrica

O Laboratório de Psicopatologia e Terapêutica Psiquiátrica é ligado ao Departamento de Psiquiatria da Faculdade de Medicina da Universidade de São Paulo (FMUSP).

Linhas de pesquisa: aspectos psicossociais dos transtornos mentais; epidemiologia dos transtornos mentais; epidemiologia psiquiátrica; metabolismo do glóbulo vermelho; personalidade; psicofarmacologia clínica; psicofisiologia clínica; psicometria; transtorno obsessivo-compulsivo e outros transtornos ansiosos na infância e adolescência.

Site oficial:


Recent Submissions

  1. (Re) thinking urban mental health from the periphery of Sao Paulo in times of the COVID-19 pandemic

    INTERNATIONAL REVIEW OF PSYCHIATRY, v.34, n.1, Special Issue, p.78-88, 2022

    Urban mental health studies traditionally search for causal relationships between elements of the city and the prevalence of mental disorders. This paper discusses the importance of (re)thinking the 'lived urban experience' from the perspective of city residents about how the immediate environmen...

  2. The Burden of Dementia due to Down Syndrome, Parkinson's Disease, Stroke, and Traumatic Brain Injury: A Systematic Analysis for the Global Burden of Disease Study 2019

    NEUROEPIDEMIOLOGY, v.55, n.4, p.286-296, 2021

    Background: In light of the increasing trend in the global number of individuals affected by dementia and the lack of any available disease-modifying therapies, it is necessary to fully understand and quantify the global burden of dementia. This work aimed to estimate the proportion of dementia d...

  3. Physical activity as an adjuvant therapy for depression and influence on peripheral inflammatory markers: A randomized clinical trial

    MENTAL HEALTH AND PHYSICAL ACTIVITY, v.22, article ID 100442, 8p, 2022

    Introduction: Regular exercise is recommended for people with major depressive disorder (MDD) by major treatment guidelines (e.g. the NICE guideline, 2009). In addition, an effect of antidepressant (AD) treatment on pro-inflammatory markers has been reported. However, it remains unclear whether p...

  4. Patterns and correlates of patient-reported helpfulness of treatment for common mental and substance use disorders in the WHO World Mental Health Surveys

    WORLD PSYCHIATRY, v.21, n.2, p.272-286, 2022

    Patient-reported helpfulness of treatment is an important indicator of quality in patient-centered care. We examined its pathways and predictors among respondents to household surveys who reported ever receiving treatment for major depression, generalized anxiety disorder, social phobia, specific...

  5. Trends in complementary and alternative medicine for the treatment of common mental disorders: A bibliometric analysis of two decades


    Objective: To investigate the trend of scientific production in relation to the modalities of CAM adopted for the treatment of common mental disorders (CMD), and the evolution and distribution of relevant articles. Material and methods: A bibliometric analysis of studies published between 2001 an...

  6. Subjective sleep quality before and during the COVID-19 pandemic in a Brazilian rural population

    SLEEP HEALTH, v.8, n.2, p.167-174, 2022

    Objectives: Prior studies have examined sleep during the coronavirus disease 2019 (COVID-19) pandemic, but have few compared sleep measured both during and prior to COVID. We examined the impact of the COVID-19 pandemic on subjective sleep quality in general and separately by gender and age (<50 ...

  7. Meta-Analysis: Efficacy and Tolerability of Vesicular Monoamine Transporter Type 2 Inhibitors in the Treatment of Tic Disorders

    MOVEMENT DISORDERS, v.37, n.4, p.684-693, 2022

    Vesicular monoamine transporter type 2 (VMAT2) inhibitors may be an effective therapy for chronic tic disorders (CTD), including Tourette syndrome (TS), but there has not been a meta-analysis compiling available evidence from randomized controlled trials (RCTs). We performed a systematic review a...


    PSYCHIATRIA DANUBINA, v.34, n.1, p.126-132, 2022

    Background: The COVID-19 is a highly transmissible disease caused by a new zoonotic coronavirus called SARS-CoV-2 that has led to several health, social, and economic issues worldwide. Anxiety and stress are predominant symptoms in the population during the quarantine; also, levels of fear or pho...

  9. Psychiatric emergency units in Brazil: a cross-sectional study

    REVISTA DA ASSOCIACAO MEDICA BRASILEIRA, v.68, n.5, p.622-626, 2022

    OBJECTIVES: This study aimed to identify the infrastructure (e.g., availability, resources, and staff), basic metrics, and problems (e.g., network, overcrowding, resources, and infrastructure) of the psychiatric emergency services in Brazil. METHODS: This is a cross-sectional study assessing psyc...

  10. Exploring nicotine dependence treatment commitment and quality of care among Portuguese substance use disorder treatment professionals

    JOURNAL OF SUBSTANCE ABUSE TREATMENT, v.134, Special Issue, article ID 108541, 5p, 2022

    Background: Smoking is highly prevalent among individuals with substance use disorder (SUD). No specific treatment policy exists for nicotine dependence treatment (NDT) in patients with SUD in Portugal, such as in most countries.& nbsp;Methods: We used the Index of Treatment Quality (ITTQ) and To...