LIM/26 - Laboratório de Pesquisa em Cirurgia Experimental

O Laboratório de Pesquisa em Cirurgia Experimental é ligado ao Departamento de Cirurgia da Faculdade de Medicina da Universidade de São Paulo (FMUSP).

Linhas de pesquisa: trauma, choque, sepse, substitutos artificiais do sangue, isquemia e reperfusão, disfunção de múltiplos órgãos, transplantes, pré-condicionamento isquêmico; células-tronco na paraplegia; substitutos vasculares; reposição volêmica; soluções hiperténicas; perfusão esplâncnica; marcadores prognósticos de tumor; angiogênese; imunopatologia de modelos experimentais; imunologias de modelos experimentais; cirurgia minimamente invasiva; oncologia experimental; morfologia e biomecânica da aorta.

Site oficial: http://limhc.fm.usp.br/portal/lim26-laboratorio-de-pesquisa-em-cirurgia-experimental/

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Recent Submissions

  1. The Immunometabolic Roles of Various Fatty Acids in Macrophages and Lymphocytes

    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, v.22, n.16, article ID 8460, 16p, 2021

    Macrophages and lymphocytes demonstrate metabolic plasticity, which is dependent partly on their state of activation and partly on the availability of various energy yielding and biosynthetic substrates (fatty acids, glucose, and amino acids). These substrates are essential to fuel-based metaboli...

  2. Changes in the Gut Bacteria Composition of Healthy Men with the Same Nutritional Profile Undergoing 10-Week Aerobic Exercise Training: A Randomized Controlled Trial

    NUTRIENTS, v.13, n.8, article ID 2839, 19p, 2021

    Nutrient consumption and body mass index (BMI) are closely related to the gut microbiota, and exercise effects on gut bacteria composition may be related to those variables. Thus, we aimed to investigate the effect of 10-week moderate aerobic exercise on the cardiorespiratory fitness and gut bact...

  3. Endoscopic approach to complex gastric tube stricture after laparoscopic sleeve gastroplasty: a case report

    ENDOSCOPY, v.53, n.10, p.E396-E397, 2021

  4. Post-acute sequelae of SARS-CoV-2 infection (PASC): a protocol for a multidisciplinary prospective observational evaluation of a cohort of patients surviving hospitalisation in Sao Paulo, Brazil

    BMJ OPEN, v.11, n.6, article ID e051706, 9p, 2021

    Introduction COVID-19 may lead to persistent and potentially incapacitating clinical manifestations (post-acute sequelae of SARS-CoV-2 infection (PASC)). Using easy-to-apply questionnaires and scales (often by telephone interviewing), several studies evaluated samples of COVID-19 inpatients from ...

  5. Inflammatory markers assessment in an animal model of intracranial hypertension: a randomized trial

    INTENSIVE CARE MEDICINE EXPERIMENTAL, v.9, n.1, article ID 42, 13p, 2021

    Background: Intracranial hypertension (ICH) is a common final pathway of most neurosurgical pathologies and leads to poor prognosis if not detected and treated properly. Inflammatory markers have been assessed in clinical scenarios of neurological injuries, in which systemic and brain tissue aggr...

  6. Posterior-superior insular deep transcranial magnetic stimulation alleviates peripheral neuropathic pain - A pilot double-blind, randomized cross-over study

    NEUROPHYSIOLOGIE CLINIQUE-CLINICAL NEUROPHYSIOLOGY, v.51, n.4, p.291-302, 2021

    Objectives. - Peripheral neuropathic pain (pNeP) is prevalent, and current treatments, including drugs and motor cortex repetitive transcranial magnetic stimulation (rTMS) leave a substantial proportion of patients with suboptimal pain relief. Methods. - We explored the intensity and short-term d...

  7. Pain relief in chronic pancreatitis: endoscopic or surgical treatment? a systematic review with meta-analysis

    SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES, v.35, n.8, p.4085-4094, 2021

    Background and aims Pain is one of the consequences of chronic pancreatitis (CP) that has the greatest impact on the quality of life of patients. Endoscopic and surgical interventions, by producing a decrease in intraductal pancreatic pressure, can provide pain relief. This is the first systemati...

  8. Recursive partitioning analysis of factors determining infection after intracranial tumor surgery

    CLINICAL NEUROLOGY AND NEUROSURGERY, v.205, article ID 106599, 6p, 2021

    Objectives: Several factors are commonly associated with the occurrence of post-operative infection after craniotomy. However, the risk factors associated with tumor surgery have been less intensively investigated. The aim of the present study was to analyze the risk factors for infection and cat...

  9. Pancreatitis after endoscopic retrograde cholangiopancreatography: A narrative review

    WORLD JOURNAL OF GASTROENTEROLOGY, v.27, n.20, p.2495-2506, 2021

    Acute post-endoscopic retrograde cholangiopancreatography pancreatitis (PEP) is a feared and potentially fatal complication that can be as high as up to 30% in high-risk patients. Pre-examination measures, during the examination and after the examination are the key to technical and clinical succ...

  10. EUS-FNA WITH 19 OR 22 GAUGES NEEDLES FOR GASTRIC SUBEPITHELIAL LESIONS OF THE MUSCLE LAYER

    ABCD-ARQUIVOS BRASILEIROS DE CIRURGIA DIGESTIVA-BRAZILIAN ARCHIVES OF DIGESTIVE SURGERY, v.31, n.1, article ID e1350, 4p, 2018

    Background: Tissue diagnosis is required for gastric subepithelial lesions for differential diagnosis of GISTs. However, there has not been consensus about the best needle for EUS-guided sampling of these lesions. Aim: To evaluate the diagnostic yield of EUS-FNA for gastric subepithelial lesions ...