LIM/30 - Laboratório de Investigação em Cirurgia Pediátrica

O Laboratório de Investigação em Cirurgia Pediátrica é ligado ao Departamento de Pediatria da Faculdade de Medicina da Universidade de São Paulo (FMUSP).

Linhas de pesquisa: método histoquímico para pesquisa da atividade de acetilcolinesterase e biópsias intestinais; montagem do método de dosagem de procalcitonina na diferenciação entre infecção e rejeição; cirurgia fetal: modelo experimental de hérnia diafragmática congênita; treinamento e padronização técnica do transplante multivisceral; modelos de obstrução biliar em animais recém-nascidos.

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Recent Submissions

  1. Evaluation of ventricular systolic function by speckle tracking technique in patients with biliary atresia before and after liver transplantation

    SCIENTIFIC REPORTS, v.11, n.1, article ID 17807, 10p, 2021

    To evaluate the ventricular function of patients with biliary atresia (BA) before and after liver transplantation using two-dimensional speckle tracking. Observational, analytical study with healthy control group, volunteers. We recruited patients from 0 to 18 years old who were candidates for li...

  2. Esophageal substitution or esophageal elongation procedures in patients with complicated esophageal atresia? Results of a comparative study

    JOURNAL OF PEDIATRIC SURGERY, v.56, n.5, p.933-937, 2021

    Background: In newborns with complex esophageal atresia, there are situations in which a primary anastomosis cannot be safely performed. The alternative is performing a late anastomosis after the esophageal ends have gone through a period of spontaneous growth or after elongations of the distant ...

  3. Energy Drink before Exercise Did Not Affect Autonomic Recovery Following Moderate Aerobic Exercise: A Crossover, Randomized and Controlled Trial

    JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION, v.40, n.3, p.280-286, 2021

    Introduction: Energy drink (ED) intake could initiate physiological changes owing to its stimulant characteristics and, it improves endurance and athletic performance. We evaluated the acute effects of ED on autonomic heart rate (HR) control during recovery after a session of submaximal aerobic e...

  4. COVID-19 and Liver Damage: Narrative Review and Proposed Clinical Protocol for Critically ill Pediatric Patients

    CLINICS, v.75, article ID e2250, 7p, 2020

    SARS-CoV-2 shares nearly 80% of its' genomic sequence with SARS-CoV and MERS-CoV, both viruses known to cause respiratory symptoms and liver impairment. The emergence of pediatric cases of multisystem inflammatory syndrome related to the SARS-CoV-2 infection (PIM-TS) has raised concerns over the ...

  5. Sepsis and cirrhosis in growing animals: description of a new experimental model and its pathological and immunological reliability

    CLINICS, v.75, article ID e1858, 8p, 2020

    OBJECTIVES: In cirrhotic children, infection events and sepsis are more frequent and more severe due to immune dysfunction. The objectives of the current study were therefore to develop an experimental model of infection and sepsis in cirrhotic weaning growing rats, by the use of bile duct ligati...


    REVISTA PAULISTA DE PEDIATRIA, v.39, p.e2019190, 2021

    ABSTRACT Objective: To assess personal, professional, medical, and scientific educational characteristics and issues reported by pediatricians. Methods: Cross-sectional study based on an online survey including 614 pediatricians who graduated in the last 15 years at a University Pediatric Departm...

  7. Heal exclusion for pruritus treatment in children with progressive familial intrahepatic cholestasis and other cholestatic diseases

    JOURNAL OF PEDIATRIC SURGERY, v.55, n.7, p.1385-1391, 2020

    Background: Pruritus is a major health-related quality-of-life burden in progressive familial intrahepatic cholestasis (PFIC) and other childhood cholestatic liver diseases. Several nontransplant surgical techniques were developed in an attempt to ameliorate symptoms and slow disease progression....

  8. Low incidence of COVID-19 in children and adolescent post-liver transplant at a Latin American reference center

    CLINICS, v.75, article ID e1986, 2p, 2020

  9. Bioprosthesis versus Mechanical Valve Heart Prosthesis: Assessment of Quality of Life


    Abstract Background: The aim of this study was to evaluate the QoL of patients undergoing heart valve replacement using the SF-36 questionnaire, compare it between patients with mechanical prosthesis and patients with bioprosthesis, and correlate the results with sociodemographic variables. Objec...

  10. Non-Alcoholic Cirrhosis and Heart Rate Variability: A Systematic Mini-Review

    MEDICINA-LITHUANIA, v.56, n.3, article ID 116, 11p, 2020

    Background and Objectives: Cirrhosis is a liver disease that causes about one million deaths annually worldwide. The estimated cirrhosis prevalence ranges from 4.5-9.5% in the general population. Up to 40% of cirrhotic patients are asymptomatic and may be diagnosed late. Studies have described th...