Please use this identifier to cite or link to this item: https://observatorio.fm.usp.br/handle/OPI/37146
Title: Intraocular pressure (IOP) after intravitreal dexamethasone implant (Ozurdex) amongst different geographic populations-GEODEX-IOP study
Authors: SHARMA, AshishKUPPERMANN, Baruch D.BANDELLO, FrancescoLANZETTA, PaoloZUR, DinahPARK, Sung WookYU, Hyeong GonSARAVANAN, V. R.ZACHARIAS, Leandro CabralBARREIRA, Alan K.IGLICKI, MatiasMIASSI, FernandoVERITTI, DanieleTSAO, SeanMAKAM, DeepikaJAIN, NidheeLOEWENSTEIN, Anat
Citation: EYE, v.34, n.6, p.1063-1068, 2020
Abstract: Purpose To analyse the intraocular pressure rise after intravitreal dexamethasone implant (Ozurdex) amongst different geographic populations. Methods The medical charts of 294 dexamethasone implants between February 2011 and 2017 were reviewed retrospectively. South Asian (India), White (Europe, US and Israel) Latino (Argentina and Brazil) patient data was included in the study. Ocular hypertension (OHT) was defined as intraocular pressure of >25 mmHg or an increase of at least 10 mmHg from baseline. The main indications for treatment were diabetic macular edema (ME) (65.6%), retinal vein occlusion (26.5%), uveitis (7.8%). Results Amongst 294 intravitreal implants, ocular hypertension (>25 mmHg) was recorded in 0, 8 and 9.5% in White, Latino, and South Asian groups, respectively. However, IOP > 20 mmHg was recorded in 14%, 28% and 27% in White, Latino, and South Asian groups, respectively. Incidence of very high IOP (>35 mmHg) was lower in all geographical groups. It was 3% in Latino followed by 2% in South Asian group. Conclusion Latino and South Asian groups have higher IOP rise compared to White population. Most patients with elevated IOP fluctuate between 20-25 mmHg.
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Artigos e Materiais de Revistas Científicas - HC/ICHC
Instituto Central - HC/ICHC

Artigos e Materiais de Revistas Científicas - LIM/33
LIM/33 - Laboratório de Oftalmologia


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