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Please use this identifier to cite or link to this item: https://observatorio.fm.usp.br/handle/OPI/37150
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dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.authorCASANOVA, Manuel F.
dc.contributor.authorSOKHADZE, Estate M.
dc.contributor.authorCASANOVA, Emily L.
dc.contributor.authorOPRIS, Ioan
dc.contributor.authorABUJADI, Caio
dc.contributor.authorMARCOLIN, Marco Antonio
dc.contributor.authorLI, Xiaoli
dc.date.accessioned2020-08-20T13:27:38Z
dc.date.available2020-08-20T13:27:38Z
dc.date.issued2020
dc.identifier.citationPSYCHIATRIC CLINICS OF NORTH AMERICA, v.43, n.2, p.229-248, 2020
dc.identifier.issn0193-953X
dc.identifier.urihttps://observatorio.fm.usp.br/handle/OPI/37150
dc.description.abstractThe presence of heterotopias, increased regional density of neurons at the gray-white matter junction, and focal cortical dysplasias all suggest an abnormality of neuronal migration in autism spectrum disorder (ASD). The abnormality is borne from a dissonance in timing between radial and tangentially migrating neuroblasts to the developing cortical plate. The uncoupling of excitatory and inhibitory cortical cells disturbs the coordinated interactions of neurons within local networks, thus providing abnormal patterns of brainwave activity in the gamma bandwidth. In ASD, gamma oscillation abnormalities and autonomic markers offer measures of therapeutic progress and help in the identification of subgroups.eng
dc.description.sponsorshipNational Institutes of HealthUnited States Department of Health & Human ServicesNational Institutes of Health (NIH) - USA [MH86784]
dc.language.isoeng
dc.publisherW B SAUNDERS CO-ELSEVIER INCeng
dc.relation.ispartofPsychiatric Clinics of North America
dc.rightsrestrictedAccesseng
dc.subjectTranscranial magnetic stimulationeng
dc.subjectAutism spectrum disordereng
dc.subjectMinicolumnseng
dc.subjectGamma oscillationseng
dc.subjectExecutive functioneng
dc.subject.othersynchronized gamma-oscillationseng
dc.subject.otherdorsolateral prefrontal cortexeng
dc.subject.otherspectrum disordereng
dc.subject.othergap-junctionseng
dc.subject.otherparvalbumin interneuronseng
dc.subject.otherfrequency oscillationseng
dc.subject.othercortical inhibitioneng
dc.subject.othergabaergic synapseseng
dc.subject.otherexecutive functioneng
dc.subject.otherillusory figureseng
dc.titleTranslational Neuroscience in Autism From Neuropathology to Transcranial Magnetic Stimulation Therapieseng
dc.typearticleeng
dc.rights.holderCopyright W B SAUNDERS CO-ELSEVIER INCeng
dc.identifier.doi10.1016/j.psc.2020.02.004
dc.identifier.pmid32439019
dc.subject.wosPsychiatryeng
dc.type.categoryoriginal articleeng
dc.type.versionpublishedVersioneng
hcfmusp.author.externalCASANOVA, Manuel F.:Greenville Hlth Syst, Dept Pediat, Div Dev Behav Pediat, 200 Patewood Dr,Suite A200, Greenville, SC 29615 USA
hcfmusp.author.externalSOKHADZE, Estate M.:Univ South Carolina, Sch Med Greenville, 200 Patewood Dr, Greenville, SC 29615 USA
hcfmusp.author.externalCASANOVA, Emily L.:Univ South Carolina, Sch Med Greenville, 200 Patewood Dr, Greenville, SC 29615 USA
hcfmusp.author.externalOPRIS, Ioan:Univ Miami, Miller Sch Med, Dept Miami Project Cure Paralysis, Miami, FL 33136 USA
hcfmusp.author.externalABUJADI, Caio:Univ Sao Paulo, Fac Med, Dept Psychiat, Sao Paulo, Brazil
hcfmusp.author.externalLI, Xiaoli:Beijing Normal Univ, State Key Lab Cognit Neurosci & Learning, Beijing, Peoples R China; Beijing Normal Univ, IDG McGovern Inst Brain Res, Beijing, Peoples R China
hcfmusp.description.beginpage229
hcfmusp.description.endpage248
hcfmusp.description.issue2
hcfmusp.description.volume43
hcfmusp.origemWOS
hcfmusp.origem.idWOS:000534683000003
hcfmusp.origem.id2-s2.0-85082880154
hcfmusp.publisher.cityPHILADELPHIAeng
hcfmusp.publisher.countryUSAeng
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