LIM/33 - Laboratório de Oftalmologia

O Laboratório de Oftalmologia é ligado ao Departamento de oftalmologia e otorrinolaringologia da Faculdade de Medicina da Universidade de São Paulo (FMUSP).

Linhas de pesquisa: fatores biopsicossociais na prevenção da cegueira; modelos de avaliação dos distúrbios da fisiologia do humor aquoso; investigação e tratamento das afecções da retina; protocolos de investigação e tratamento cirúrgico da disfunções dos anexos oculares e imunopatologia da superfície ocular.

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Recent Submissions

  1. p Epithelial Basement Membrane Regeneration After PRK-Induced Epithelial-Stromal Injury in Rabbits: Fibrotic Versus Non-fibrotic Corneal Healing

    JOURNAL OF REFRACTIVE SURGERY, v.38, n.1, p.50-+, 2022

    PURPOSE: To study epithelial basement membrane (EBM) regeneration in non-fibrotic and fibrotic corneas after photorefractive keratectomy (PRK). METHODS: Rabbits (120 total) had either epithelial scrape alone,-4.50 diopters (D) PRK,-9.00 D PRK, or no surgery. Immunohistochemistry was performed on ...

  2. Spontaneous closure of a chronic full-thickness idiopathic macular hole after Irvine-Gass syndrome resolution

    BMC OPHTHALMOLOGY, v.22, n.1, article ID 132, 5p, 2022

    Background Full-thickness idiopathic macular hole (IMH) usually causes serious visual deformities and visual acuity loss. Pseudophakic cystic macular edema, also known as Irvine-Gass syndrome, is another entity that causes visual disturbances, and occurs mainly after cataract extraction. We prese...

  3. Topical losartan inhibits corneal scarring fibrosis and collagen type IV deposition after Descemet's membrane-endothelial excision in rabbits

    EXPERIMENTAL EYE RESEARCH, v.216, article ID 108940, 9p, 2022

    The purpose of this study was to examine the effect of topical and/or oral angiotensin converting enzyme II inhibitor and TGF-beta signaling blocker losartan on corneal stromal fibrosis that developed in rabbit corneas after Descemetorhexis removal of central Descemet's membrane and corneal endot...

  4. Avoiding Complications on the Upper Face Treatment With Botulinum Toxin: A Practical Guide

    AESTHETIC PLASTIC SURGERY, v.46, n.1, p.385-394, 2022

    Background Currently, botulinum toxin (BoNT) injections are the most commonly performed non-invasive procedure for rejuvenation on the upper face. The therapeutic use of botulinum toxin has generally been safe and well tolerated. Adverse effects are considered mild, transient, and self-limited. H...

  5. Comparison of Visual Evoked Potentials in Patients Affected by Optic Neuritis From Multiple Sclerosis or Neuromyelitis Optica Spectrum Disorder

    JOURNAL OF NEURO-OPHTHALMOLOGY, v.42, n.1, p.E32-E39, 2022

    Purpose: To compare the visual evoked potentials (VEPs) of optic neuritis (ON) patients with multiple sclerosis (MS), neuromyelitis optica spectrum disorder (NMOSD), and controls. To evaluate correlations between VEP and optical coherence tomography (OCT), contrast sensitivity (CS), and automated...

  6. Variability and Power to Detect Progression of Different Visual Field Patterns

    OPHTHALMOLOGY GLAUCOMA, v.4, n.6, p.617-623, 2021

    Purpose: To compare the variability and ability to detect visual field (VF) progression of 24-2, central 12 locations of the 24-2 and 10-2 VF tests in eyes with abnormal VFs. Design: Retrospective, multisite cohort. Participants: A total of 52 806 24-2 and 11 966 10-2 VF tests from 7307 eyes from...

  7. A randomized comparative study of inferomedial vs. balanced orbital decompression. Analysis of changes in orbital volume, eyelid parameters, and eyeball position

    EYE, v.36, n.3, p.547-554, 2022

    Background/objectives The objective of this study is to investigate and compare changes in orbital volume, eyelid parameters, and eyeball position after inferomedial and balanced (medial + deep lateral walls) orbital decompression (OD) in patients with Graves' orbitopathy (GO). Subjects/methods P...


    RETINAL CASES & BRIEF REPORTS, v.15, p.S11-S20, 2021

  9. Impact of cataract surgery on visual acuity and quality of life assessed using the National Eye Institute Visual Function Questionnaire 25 in a public teaching hospital in Brazil


    ABSTRACT Purpose: This study set out to examine the impact of surgical treatment of senile cataract on visual acuity and quality of life in patients operated in a public teaching hospital. Methods: Prospective study including patients aged over 60 years with clinical indications for cataract surg...

  10. Fingerprint sign in Vogt-Koyanagi-Harada disease: a case series

    INTERNATIONAL JOURNAL OF RETINA AND VITREOUS, v.8, n.1, article ID 7, 8p, 2022

    Background The tomographic finding, which has been called the ""fingerprint sign"" in en face reconstructions, seems to be the result of a variety of processes that cause distension of the outer plexiform layer (OPL) and the Henle fiber layer (HFL). The aim of this paper is to describe the appear...