LIM/37 - Laboratório de Transplante e Cirurgia de Fígado

O Laboratório de Transplante e Cirurgia do Fígado é ligado ao Departamento de Gastroenterologia da Faculdade de Medicina da Universidade de São Paulo (FMUSP).

Linhas de pesquisa: rejeição hiperaguda, indução de tolerância imunológica, isquemia, reperfusão em transplante de fígado, pâncreas e ilhotas pancreáticas; intestino, multivisceral e reto anal; regeneração hepática e reperfusão hepática e pancreática; insuficiência hepática aguda; fisiopatologia da pancreatite aguda; biologia molecular de tumores do fígado e pâncreas; câncer hepático experimental; choque hemorrágico experimental; microcirurgia vascular; aspectos hemodinâmicos da hipertensão portal.

Site oficial: http://limhc.fm.usp.br/portal/lim37-laboratorio-de-transplante-e-cirurgia-do-figado/

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Recent Submissions

  1. Guidelines for Perioperative Care for Liver Transplantation: Enhanced Recovery After Surgery (ERAS) Recommendations

    TRANSPLANTATION, v.106, n.3, p.552-561, 2022

    Background. Enhanced Recovery After Surgery (ERAS) is a multimodal, evidence-based, program of care developed to minimize the response to surgical stress, associated with reduced perioperative morbidity and hospital stay. This study presents the specific ERAS Society recommendations for liver tra...

  2. Anorectal Transplantation The First Long-term Success in a Canine Model

    ANNALS OF SURGERY, v.275, n.4, p.E636-E644, 2022

    Objective: Anorectal transplantation is a challenging procedure but a promising option for patients with weakened or completely absent anorectal function. Summary Background Data: We constructed a canine model of anorectal transplantation, evaluated the long-term outcomes, and controlled rejectio...

  3. A Brazilian Inter-Hospital Candidemia Outbreak Caused by Fluconazole-Resistant Candida parapsilosis in the COVID-19 Era

    JOURNAL OF FUNGI, v.8, n.2, article ID 100, 8p, 2022

    Horizontal transmission of fluconazole-resistant Candida parapsilosis (FRCP) through healthcare workers' hands has contributed to the occurrence of candidemia outbreaks worldwide. Since the first COVID-19 case in Brazil was detected in early 2020, hospitals have reinforced hand hygiene and disinf...

  4. Histopathological factors versus margin size in single colorectal liver metastases: Does a 1-cm margin size matter?

    SCANDINAVIAN JOURNAL OF SURGERY, v.111, n.1, article ID 14574969211069329, 8p, 2022

    Background and objective: The ideal margin width for surgical resection of colorectal liver metastases has been extensively studied, but not sufficiently in accordance with other pathological factors. The aim of this study was to assess for the first time the prognostic impact of margin widths ac...

  5. Impact of Three Methods of Ischemic Preconditioning on Ischemia-Reperfusion Injury in a Pig Model of Liver Transplantation

    JOURNAL OF INVESTIGATIVE SURGERY, v.35, n.4, p.900-909, 2022

    Background Ischemic preconditioning (IPC), either direct (DIPC) or remote (RIPC), is a procedure aimed at reducing the harmful effects of ischemia-reperfusion (I/R) injury. Objectives To assess the local and systemic effects of DIPC, RIPC, and both combined, in the pig liver transplant model. Mat...

  6. Propensity Score and Desirability of Outcome Ranking Analysis of Ertapenem for Treatment of Nonsevere Bacteremic Urinary Tract Infections Due to Extended-Spectrum-Beta-Lactamase-Producing Enterobacterales in Kidney Transplant Recipients

    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, v.65, n.11, article ID e01102-21, 13p, 2021

    There are scarce data on the efficacy of ertapenem in the treatment of bacteremia due to extended-spectrum-beta-lactamase (ESBL)-producing Enterobacterales (ESBL-E) in kidney transplant (KT) recipients. We evaluated the association between treatment with ertapenem or meropenem and clinical cure i...

  7. Experimental model of portal hypertension and esophagogastric varices in minipigs: pressure and endoscopic pilot study

    ACTA CIRURGICA BRASILEIRA, v.37, n.1, article ID e370103, 8p, 2022

    Introduction: Portal hypertension still represents an important health problem worldwide. In the search for knowledge regarding this syndrome, experimental studies with animal models have proven to be useful to point the direction to be taken in future randomized clinical trials. Purpose: To vali...

  8. WILLIAM ABRAO SAAD: IN MEMORIAN TO THE GRAND MASTER OF HEPATIC SURGERY!

    ABCD-ARQUIVOS BRASILEIROS DE CIRURGIA DIGESTIVA-BRAZILIAN ARCHIVES OF DIGESTIVE SURGERY, v.34, n.3, article ID e1588, 2p, 2021

  9. Risk factors for adverse events of colorectal endoscopic submucosal dissection: a systematic review and meta-analysis

    EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, v.33, suppl.1, p.E33-E41, 2021

    Colorectal endoscopic submucosal dissection (ESD) is already an established treatment for superficial colorectal tumors. However, its technical difficulty and high adverse events rates, compared to endoscopic piecemeal mucosal resection, are a concern to some specialists and have probably contrib...

  10. Long-term results of an endoscopic screening program for superficial esophageal cancer in patients with head and neck squamous cell carcinoma

    ENDOSCOPY INTERNATIONAL OPEN, v.10, n.2, p.E200-E208, 2022

    Background and study aims Patients with head and neck squamous cell carcinoma (HNSCC) are at risk of a second primary tumor in the gastrointestinal tract, most commonly in the esophagus. Screening these patients for esophageal carcinoma may help detect asymptomatic dysplasia and early cancer, thu...