LIM/49 - Laboratório de Protozoologia
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Ongoing host-shift speciation in Plasmodium simium
TRENDS IN PARASITOLOGY, v.37, n.11, p.940-942, 2021
Plasmodium simium, a malaria parasite that infects platyrrhine monkeys and humans in the New World, is nearly identical to Plasmodium vivax. Recent genomic comparative analyses of these sister species have identified elevated divergence in a gene that may underlie P. simium adaptation to non-huma...
Four Corners: an educational strategy for learning infectious diseases in medical school
REVISTA BRASILEIRA DE EDUCAçãO MéDICA, v.45, n.3, p.e142, 2021
Abstract: Introduction: An extensive literature has demonstrated the benefits of active learning in medical education and has revealed the need for updating the teaching methodologies. Active learning strategies consolidate the theoretical knowledge, while simultaneously encouraging the student´s...
Residual malaria of Atlantic Forest systems and the influence of anopheline fauna
PARASITOLOGY RESEARCH, v.120, n.8, p.2759-2767, 2021
In Brazil, the Amazon region comprises 99.5% of the reported malaria cases. However, another hotspot of the disease is the Atlantic Forest regions, with the sporadic occurrence of autochthonous human cases. In such context, this study sought to investigate the role of anopheline mosquitoes (Dipte...
Neurological manifestations in people living with HIV/AIDS in the late cART era: a prospective observational study at a tertiary healthcare center in Sao Paulo, Brazil
HIV RESEARCH & CLINICAL PRACTICE, v.22, n.4, p.87-95, 2021
Background:The aim of this study was to evaluate the frequency, spectrum, in-hospital mortality rate, and factors associated with death in people living with HIV/AIDS (PLWHA) presenting with neurological diseases from a middle-income country, as well as estimate its one-year global death rate. Me...
Surveillance of post-cataract endophthalmitis at a tertiary referral center: a 10-year critical evaluation
INTERNATIONAL JOURNAL OF RETINA AND VITREOUS, v.7, n.1, article ID 14, 6p, 2021
BackgroundAcute post-cataract endophthalmitis (APE) is a rare complication potentially causing irreversible visual loss. A 10-year study of APE was conducted to determine its incidence, microbiological spectra and antibiotic resistance profile of APE-related pathogens at a major tertiary referral...
Combining urine antigen and blood polymerase chain reaction for the diagnosis of disseminated histoplasmosis in hospitalized patients with advanced HIV disease
MEDICAL MYCOLOGY, v.59, n.9, p.916-922, 2021
Disseminated histoplasmosis (DH) is endemic in Latin America and the Caribbean where diagnostic tools are restricted. We carried-out a 1-year prospective cohort study at a referral hospital in SAo Paulo, Brazil. Participants had > or =18 years old, were hospitalized due to any indication and had ...
Tocilizumab in SARS-COVID19 following postoperative laparoscopic transhiatal esophagectomy for the adenocarcinoma of esophagogastric tumor: A case report
INTERNATIONAL JOURNAL OF SURGERY CASE REPORTS, v.86, article ID 106343, 4p, 2021
Introduction and importance: Esophagectomy for esophageal cancer is one of the most challenging surgical procedures, with high rates of morbidity, especially from respiratory complications. SARS-COVID19 represents a health threat nowadays. Peri-operative SARS-COVID19 infection after esophagectomy...
Loss of forest cover and host functional diversity increases prevalence of avian malaria parasites in the Atlantic Forest
INTERNATIONAL JOURNAL FOR PARASITOLOGY, v.51, n.9, p.719-728, 2021
Host phylogenetic relatedness and ecological similarity are thought to contribute to parasite community assembly and infection rates. However, recent landscape level anthropogenic changes may disrupt hostparasite systems by impacting functional and phylogenetic diversity of host communities. We e...
Serum antibodies blocked by glycan antigens in canine visceral leishmaniasis serology are mostly IgA immune complexes
PARASITOLOGY, v.148, n.12, p.1509-1515, 2021
Immune complexes (ICs) are found in canine visceral leishmaniasis (CVL) and interfere with the serum detection of antibodies. Dissociation of these monovalent complexes by dissociative enzyme-linked immunosorbent assay (ELISA) removes false-negative results and allows some characterization of ant...
Post-acute sequelae of SARS-CoV-2 infection (PASC): a protocol for a multidisciplinary prospective observational evaluation of a cohort of patients surviving hospitalisation in Sao Paulo, Brazil
BMJ OPEN, v.11, n.6, article ID e051706, 9p, 2021
Introduction COVID-19 may lead to persistent and potentially incapacitating clinical manifestations (post-acute sequelae of SARS-CoV-2 infection (PASC)). Using easy-to-apply questionnaires and scales (often by telephone interviewing), several studies evaluated samples of COVID-19 inpatients from ...