LIM/51 - Laboratório de Emergências Clínicas

O Laboratório de Emergências Clínicas é ligado ao Departamento de Clínica Médica da Faculdade de Medicina da Universidade de São Paulo (FMUSP).

Linhas de pesquisa: lesão de isquemia-reperfusão; fisiopatologia da sepse; mecanismos inflamatórios na aterosclerose; sinalização celular por espécies reativas de nitrogênio; arritmias cardíacas; interação entre receptores nucleares e inflamatórios.

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Recent Submissions

  1. Chagas disease is not associated with diabetes, metabolic syndrome, insulin resistance and beta cell dysfunction at baseline of Brazilian Longitudinal Study of Adult Health (ELSA-Brasil)

    PARASITOLOGY INTERNATIONAL, v.85, article ID 102440, 6p, 2021

    Chagas disease (ChD) affects millions of people worldwide, being endemic in Latin America and emerging in the United States and Europe. Classically described as targeting the heart and gastrointestinal tract, Trypanosoma cruzi parasitism leads to structural and pro-inflammatory changes in the adi...

  2. Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021

    INTENSIVE CARE MEDICINE, v.47, n.11, p.1181-1247, 2021

  3. Fluid management in diabetic ketoacidosis: new tricks for old dogs?

    INTENSIVE CARE MEDICINE, v.47, n.11, p.1312-1314, 2021

  4. Executive Summary: Surviving Sepsis Campaign: International Guidelines for the Management of Sepsis and Septic Shock 2021

    CRITICAL CARE MEDICINE, v.49, n.11, p.1974-1982, 2021

  5. Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2021

    CRITICAL CARE MEDICINE, v.49, n.11, p.E1063-E1143, 2021

  6. Are mobile phones part of the chain of transmission of SARS- CoV-2 in hospital settings?


    Mobile phones (MPs) have become an important work tool around the world including in hospitals. We evaluated whether SARS-CoV-2 can remain on the surface of MPs of first-line healthcare workers (HCW) and also the knowledge of HCWs about SARS-CoV-2 cross-transmission and conceptions on the virus s...

  7. Applicability of the GLIM criteria for the diagnosis of malnutrition in older adults in the emergency ward: A pilot validation study

    CLINICAL NUTRITION, v.40, n.11, p.5447-5456, 2021

    Background & aims: Acutely ill older adults are at higher risk of malnutrition. This study aimed to explore the applicability and accuracy of the GLIM criteria to diagnose malnutrition in acutely ill older adults in the emergency ward (EW). Methods: We performed a retrospective secondary analysis...

  8. The Prognosis of Coronary Artery Disease in a Brazilian Community Hospital: Findings from the ERICO Study

    ARQUIVOS BRASILEIROS DE CARDIOLOGIA, v.117, n.5, p.978-985, 2021

    Background: Long-term prognosis post-acute coronary syndrome (ACS) in secondary care is not well-known. The severity of coronary artery disease (CAD) as a predictor of long-term mortality was evaluated in a community hospital in Brazil. Objective: We aimed to compare short and long-term prognosis...

  9. Lack of association between proton pump inhibitor use and decline in cognitive performance in the ELSA-Brasil cohort

    EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, v.77, n.11, p.1725-1735, 2021

    Objective The study aims to investigate the longitudinal association of use and time of use of proton pump inhibitors (PPIs) with decreased performance in three cognitive tests. Methods Prospective cohort study included 7115 participants with mean age of 58.9 years at baseline (2008-2010) who par...

  10. Physical inactivity and headache disorders: Cross-sectional analysis in the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil)

    CEPHALALGIA, v.41, n.14, p.1467-1485, 2021

    Background Physical inactivity has been linked to headache disorders but estimates based on the current World Health Organization physical activity guidelines are unknown. Objective To test the associations between headache disorders and physical inactivity in the ELSA-Brasil cohort. Methods In a...