LIM/51 - Laboratório de Emergências Clínicas

O Laboratório de Emergências Clínicas é ligado ao Departamento de Clínica Médica da Faculdade de Medicina da Universidade de São Paulo (FMUSP).

Linhas de pesquisa: lesão de isquemia-reperfusão; fisiopatologia da sepse; mecanismos inflamatórios na aterosclerose; sinalização celular por espécies reativas de nitrogênio; arritmias cardíacas; interação entre receptores nucleares e inflamatórios.

Site oficial: http://limhc.fm.usp.br/portal/lim51-laboratorio-de-emergencias-clinicas/

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Recent Submissions

  1. HEMOCOVID-19 Study: An International Clinical Study to Evaluate Microvascular and Endothelial Impairments in Severe COVID-19 Patients Using Near-Infrared Spectroscopy

    TRANSLATIONAL BIOPHOTONICS: DIAGNOSTICS AND THERAPEUTICS, v.11919, article ID 1191917, 3p, 2021

    We present the HEMOCOVID-19 study spanning four countries and eight hospitals where near-infrared spectroscopy is utilized to evaluate microvascular and endothelial health of severe COVID-19 patients at the intensive care.

  2. The symbiotic supplementation modulate gut microbiota, regulation beta-catenin expression and prevents weight gain in ob/ob mice with non-alcoholic fatty liver disease (NAFLD)

    JOURNAL OF HEPATOLOGY, v.73, suppl.1, p.S658-S658, 2020

  3. Plano de análise estatística de um ensaio clínico randomizado em cluster em unidades de terapia intensiva geral adulto no Brasil: TELE-critical care verSus usual Care On ICU PErformance (TELESCOPE)

    REVISTA BRASILEIRA DE TERAPIA INTENSIVA, v.34, n.1, p.87-95, 2022

    ABSTRACT Objective: The TELE-critical Care verSus usual Care On ICU PErformance (TELESCOPE) trial aims to assess whether a complex telemedicine intervention in intensive care units, which focuses on daily multidisciplinary rounds performed by remote intensivists, will reduce intensive care unit l...

  4. Intubação traqueal em paciente com COVID-19 no Brasil: um inquérito nacional

    REVISTA BRASILEIRA DE TERAPIA INTENSIVA, v.34, n.1, p.202-204, 2022

  5. Diretrizes Brasileiras para o tratamento farmacológico de pacientes hospitalizados com COVID-19: Diretriz conjunta da Associação Brasileira de Medicina de Emergência, Associação de Medicina Intensiva Brasileira, Associação Médica Brasileira, Sociedade Brasileira de Angiologia e Cirurgia Vascular, Sociedade Brasileira de Infectologia, Sociedade Brasileira de Pneumologia e Tisiologia e Sociedade Brasileira de Reumatologia

    REVISTA BRASILEIRA DE TERAPIA INTENSIVA, v.34, n.1, p.1-12, 2022

    ABSTRACT Objective: Several therapies are being used or proposed for COVID-19, and many lack appropriate evaluations of their effectiveness and safety. The purpose of this document is to develop recommendations to support decisions regarding the pharmacological treatment of patients hospitalized ...

  6. Burnout syndrome in intensive care physicians in time of the COVID-19: a cross-sectional study

    BMJ OPEN, v.12, n.4, article ID e057272, 5p, 2022

    Objectives To assess the prevalence of burnout syndrome among intensive care physicians working in a tertiary private hospital as well as their perceived impact of the COVID-19 pandemic on their life. Design A cross-sectional study. Setting Intensive care units dedicated to the care of COVID-19 i...

  7. Methodological issues in meta-analyses of observational studies: the need for attention to the details

    BRITISH JOURNAL OF ANAESTHESIA, v.128, n.5, p.E303-E305, 2022

  8. Lung perfusion during veno-venous extracorporeal membrane oxygenation in a model of hypoxemic respiratory failure

    INTENSIVE CARE MEDICINE EXPERIMENTAL, v.10, n.1, article ID 15, 13p, 2022

    Background: Veno-venous extracorporeal membrane oxygenation (ECMO) provides blood oxygenation and carbon dioxide removal in acute respiratory distress syndrome. However, during ECMO support, the native lungs still play an important role in gas exchange, functioning as a second oxygenator in serie...

  9. Performance of NEWS, qSOFA, and SIRS Scores for Assessing Mortality, Early Bacterial Infection, and Admission to ICU in COVID-19 Patients in the Emergency Department

    FRONTIERS IN MEDICINE, v.9, article ID 779516, 12p, 2022

    SARS-CoV-2 infection has a wide spectrum of presentations, from asymptomatic to pneumonia and sepsis. Risk scores have been used as triggers for protocols that combine several interventions for early management of sepsis. This study tested the accuracy of the score SIRS, qSOFA, and NEWS in predic...

  10. Carotid intima-media thickness and flow-mediated dilation do not predict acute in-hospital outcomes in patients hospitalized with COVID-19

    AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, v.322, n.6, p.H906-H913, 2022

    Studies have suggested a potential role of endothelial dysfunction and atherosclerosis in the pathophysiology of COVID-19. Herein, we tested whether brachial flow-mediated dilation (FMD) and carotid intima-media thickness (cIMT) measured upon hospital admission are associated with acute in-hospit...