LIM/52 - Laboratório de Virologia

O Laboratório de Virologia é ligado ao Departamento de Moléstias Infecciosas e Parasitárias da Faculdade de Medicina da Universidade de São Paulo (FMUSP).

Linhas de pesquisa: infecções virais em pacientes imunodeprimidos; epidemiologia molecular das doenças virais; desenvolvimento e avaliação de métodos de métodos para diagnóstico de infecções virais; avaliação de vacinas em saúde pública; inquéritos soroepidemiológicos de infecções virais.

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Recent Submissions

  1. Hepatite B

    Gouvêa, Michele Soares Gomes; Pinho, João Renato Rebello; Mendes, Maria Cássia Jacintho Corrêa. Hepatite B. In: Pinho, João Renato Rebello; Ribeiro Junior, Ulysses (eds). Genômica e marcadores moleculares em gastroenterologia e hepatologia. SÃO PAULO: Sarvier, 2017. p.207-233.

  2. Technical comparison of MinIon and Illumina technologies for genotyping Chikungunya virus in clinical samples


    New-generation sequencing (NGS) techniques have brought the opportunity for genomic monitoring of several microorganisms potentially relevant to public health. The establishment of different methods with different mechanisms provides a wide choice, taking into account several aspects. With that i...

  3. Characterization of Torquetenovirus in amniotic fluid at the time of <i>in utero</i> fetal surgery: correlation with early premature delivery and respiratory distress

    FRONTIERS IN MEDICINE, v.10, article ID 1161091, 8p, 2023

    Torquetenovirus (TTV) is a commensal virus present in many healthy individuals. Although considered to be non-pathogenic, its presence and titer have been shown to be indicative of altered immune status in individuals with chronic infections or following allogeneic transplantations. We evaluated ...

  4. Association between development of severe COVID-19 and a polymorphism in the <i>CIAS1</i> gene that codes for an inflammasome component

    SCIENTIFIC REPORTS, v.13, n.1, article ID 11252, 5p, 2023

    An elevated pro-inflammatory cytokine response is associated with severe life-threatening symptoms in individuals with Coronavirus Disease-2019 (COVID). The inflammasome is an intracellular structure responsible for generation of interleukin (IL)-1 & beta; and IL-18. NALP3, a product of the CIAS1...


    ACTA CYTOLOGICA, v.67, n.4, p.388-394, 2023

    INTRODUCTION: The early identification of precursor lesions followed by appropriate treatment prevents development of cervical cancer and its consequences OBJECTIVE: The present study evaluated the influence of the Covid-19 pandemic on cervical cancer screening by comparing the quantity of tests ...

  6. Detailed characterization of Redondovirus in saliva of SARS-CoV-2-infected individuals in Sao Paulo, Brazil

    PLOS ONE, v.18, n.8, article ID e0291027, 10p, 2023

    BackgroundRedondovirus (ReDoV) is a DNA virus present in the respiratory tract of many healthy individuals. Since SARS-CoV-2, the virus responsible for COVID-19, also primarily infects the same site, we evaluated whether ReDoV was present at increased frequency in patients with COVID-19 and influ...

  7. Quantification of Torque Teno Virus (TTV) in plasma and saliva of individuals with liver cirrhosis: a cross sectional study

    FRONTIERS IN MEDICINE, v.10, article ID 1184353, 7p, 2023

    Introduction: Torque teno virus ( TTV) has been pointed as an endogenous marker of immune function, the objective of this study was to investigate the TTV viral load in plasma and saliva of cirrhotic individuals and correlate it with clinical characteristics. Methods: Blood, saliva, clinical data...

  8. Full genotype characterization of Brazilian canine G3P[3] strains during a 10-year survey (2012-2021) of rotavirus infection in domestic dogs and cats

    ARCHIVES OF VIROLOGY, v.168, n.7, article ID 176, 15p, 2023

    There is a dearth of information on the molecular epidemiology of rotaviruses in pets in Brazil. The aim of this study was to monitor rotavirus infections in household dogs and cats, determine full-genotype constellations, and obtain data on evolutionary relationships. Between 2012 and 2021, 600 ...

  9. SARS-CoV-2 Detection and Culture in Different Biological Specimens from Immunocompetent and Immunosuppressed COVID-19 Patients Infected with Two Different Viral Strains

    VIRUSES-BASEL, v.15, n.6, article ID 1270, 12p, 2023

    Introduction-The dynamics of SARS-CoV-2 shedding and replication in humans remain incompletely understood. Methods-We analyzed SARS-CoV-2 shedding from multiple sites in individuals with an acute COVID-19 infection by weekly sampling for five weeks in 98 immunocompetent and 25 immunosuppressed in...

  10. Serial dilution of semen samples and better results in HCV-PCR in patients with hepatitis C infection

    JOURNAL OF VIRAL HEPATITIS, v.19, suppl.3, Special Issue, p.6-6, 2012