LIM/52 - Laboratório de Virologia

O Laboratório de Virologia é ligado ao Departamento de Moléstias Infecciosas e Parasitárias da Faculdade de Medicina da Universidade de São Paulo (FMUSP).

Linhas de pesquisa: infecções virais em pacientes imunodeprimidos; epidemiologia molecular das doenças virais; desenvolvimento e avaliação de métodos de métodos para diagnóstico de infecções virais; avaliação de vacinas em saúde pública; inquéritos soroepidemiológicos de infecções virais.

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Recent Submissions

  1. Cone-beam computed tomography texture analysis can help differentiate odontogenic and non-odontogenic maxillary sinusitis

    IMAGING SCIENCE IN DENTISTRY, v.53, n.1, p.43-51, 2023

    Purpose: This study aimed to assess texture analysis (TA) of cone-beam computed tomography (CBCT) images as a quantitative tool for the differential diagnosis of odontogenic and non-odontogenic maxillary sinusitis (OS and NOS, respectively).Materials and Methods: CBCT images of 40 patients diagno...

  2. Noninvasive Techniques for Management of Erythema Multiforme

    CASE REPORTS IN DENTISTRY, v.2023, article ID 9938939, 4p, 2023

    An 18-year-old man was referred for a diagnosis of extensive oral lesions. During the interview, he reported a medical history of ganglionic tuberculosis, type 2 herpes infection, and significant weight loss due to dysphagia. Intraoral exam revealed multiple painful and ulcerated lesions covered ...

  3. Torquetenovirus: predictive biomarker or innocent bystander in pathogenesis

    FRONTIERS IN MEDICINE, v.10, article ID 1283454, 2p, 2023

  4. Immunoglobulin A Antibodies Against Myelin Oligodendrocyte Glycoprotein in a Subgroup of Patients With Central Nervous System Demyelination

    JAMA NEUROLOGY, v.80, n.9, p.989-995, 2023

    IMPORTANCE Differential diagnosis of patients with seronegative demyelinating central nervous system (CNS) disease is challenging. In this regard, evidence suggests that immunoglobulin (Ig) A plays a role in the pathogenesis of different autoimmune diseases. Yet little is known about the presence...

  5. Detection of coinfection with Primate Erythroparvovirus 1 and arboviruses (DENV, CHIKV and ZIKV) in individuals with acute febrile illness in the state of Rio Grande do Norte in 2016

    PLOS NEGLECTED TROPICAL DISEASES, v.17, n.11, article ID e0011701, 14p, 2023

    BackgroundArthropod-borne viruses, known as arboviruses, pose substantial risks to global public health. Dengue (DENV), Chikungunya (CHIKV) and Zika (ZIKV) viruses stand out as significant concerns in Brazil and worldwide. Their overlapping clinical manifestations make accurate diagnosis a challe...

  6. Survival analysis over a 20-year period of a Brazilian cohort of blood donors coinfected HIV-HCV

    BRAZILIAN JOURNAL OF INFECTIOUS DISEASES, v.27, n.5, article ID 102810, 6p, 2023

    Among individuals coinfected with HCV and HIV, studies of mortality from non-hepatic causes have shown inconsistent results. The aim of this study was to investigate the contribution of HCV and HIV co-infection to mortality from hepatic and non-hepatic causes in Brazil. This retrospective cohort ...

  7. Association between torquetenovirus in vaginal secretions and infertility: An exploratory metagenomic analysis

    AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY, v.90, n.5, article ID e13788, 6p, 2023

    ProblemThe association of viruses with infertility remains incompletely evaluated.Method of studyVaginal secretions from 46 women seeking treatment in the Center for Reproductive Medicine and Infertility at Weill Cornell Medicine were tested for viruses by metagenomic analysis by lab personnel bl...

  8. Hepatite B

    Gouvêa, Michele Soares Gomes; Pinho, João Renato Rebello; Mendes, Maria Cássia Jacintho Corrêa. Hepatite B. In: Pinho, João Renato Rebello; Ribeiro Junior, Ulysses (eds). Genômica e marcadores moleculares em gastroenterologia e hepatologia. SÃO PAULO: Sarvier, 2017. p.207-233.

  9. Technical comparison of MinIon and Illumina technologies for genotyping Chikungunya virus in clinical samples


    New-generation sequencing (NGS) techniques have brought the opportunity for genomic monitoring of several microorganisms potentially relevant to public health. The establishment of different methods with different mechanisms provides a wide choice, taking into account several aspects. With that i...

  10. Characterization of Torquetenovirus in amniotic fluid at the time of <i>in utero</i> fetal surgery: correlation with early premature delivery and respiratory distress

    FRONTIERS IN MEDICINE, v.10, article ID 1161091, 8p, 2023

    Torquetenovirus (TTV) is a commensal virus present in many healthy individuals. Although considered to be non-pathogenic, its presence and titer have been shown to be indicative of altered immune status in individuals with chronic infections or following allogeneic transplantations. We evaluated ...