LIM/56 - Laboratório de Investigação em Dermatologia e Imunodeficiências
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Patient with agammaglobulinemia produces anti-SARS-CoV-2 reactive T-cells after CoronaVac vaccine
CLINICS, v.77, article ID 100007, 2p, 2022
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Immunology of leprosy
INTERNATIONAL REVIEWS OF IMMUNOLOGY, v.41, n.2, p.72-83, 2022
Leprosy is a disease caused by Mycobacterium leprae (ML) with diverse clinical manifestations, which are strongly correlated with the host's immune response. Skin lesions may be accompanied by peripheral neural damage, leading to sensory and motor losses, as well as deformities of the hands and f...
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Antiviral Response Induced by Toll-Like Receptor (TLR) 7/TLR8 Activation Inhibits Human Immunodeficiency Virus Type 1 Infection in Cord Blood Macrophages
JOURNAL OF INFECTIOUS DISEASES, v.225, n.3, p.510-519, 2022
Cord blood macrophages are more susceptible to HIV-1 infection. This vulnerability can be reversed under treatment with the type I interferon adjuvant CL097, which triggers inflammatory and antiviral responses in these cells, attenuating viral replication. Vertical transmission is the main mechan...
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Clinical features of COVID-19 by SARS-CoV-2 Gamma variant: A prospective cohort study of vaccinated and unvaccinated healthcare workers
JOURNAL OF INFECTION, v.84, n.2, p.262-265, 2022
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Age-associated phenotypic imbalance in TCD4 and TCD8 cell subsets: comparison between healthy aged, smokers, COPD patients and young adults
IMMUNITY & AGEING, v.19, n.1, article ID 9, 16p, 2022
Background COPD is associated with an abnormal lung immune response that leads to tissue damage and remodeling of the lung, but also to systemic effects that compromise immune responses. Cigarette smoking also impacts on innate and adaptative immune responses, exerting dual, pro- and anti-inflamm...
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Esophageal Lichen Planus
JOURNAL OF CUTANEOUS MEDICINE AND SURGERY, v.26, n.2, p.220-220, 2022
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Some Good and Some Bad: Sand Fly Salivary Proteins in the Control of Leishmaniasis and in Autoimmunity
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY, v.12, article ID 839932, 10p, 2022
Sand flies are hematophagous insects responsible for the transmission of vector-borne diseases to humans. Prominent among these diseases is Leishmaniasis that affects the skin and mucous surfaces and organs such as liver and spleen. Importantly, the function of blood-sucking arthropods goes beyon...
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Cutaneous adverse events to systemic antineoplastic therapies: a retrospective study in a public oncologic hospital
ANAIS BRASILEIROS DE DERMATOLOGIA, v.97, n.1, p.14-21, 2022
Background: Mucocutaneous adverse events are common during anticancer treatment, with variable consequences for the patient and their therapeutic regimen. Objective: To evaluate the most common adverse events, as well as the drugs associated with their appearance and the consequences for cancer t...
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Deciphering the influence of smoking in adults with atopic dermatitis
JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY, v.36, n.3, p.324-325, 2022
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Perivascular clusters of Th2 cells and M2 macrophages in allergic contact dermatitis to methylchloroisothiazolinone and methylisothiazolinone
EXPERIMENTAL DERMATOLOGY, v.31, n.2, p.191-201, 2022
Background Methylisothiazolinone (MI) and Methylchloroisothiazolinone (MCI) are among the most common skin sensitizers, yet the immunological events that occur during MCI/MI allergic contact dermatitis (ACD) are still poorly understood. Objectives: To analyse dendrocytes, macrophage subtypes and ...
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