LIM/58 - Laboratório de Ginecologia Estrutural e Molecular

O Laboratório de Ginecologia Estrutural e Molecular é ligado ao Departamento de Obstetrícia e Ginecologia da Faculdade de Medicina da Universidade de São Paulo (FMUSP).

Linhas de pesquisa: repercussões bioquímicas, metabólicas e clínicas das diversas modalidades terapêuticas no climatério; abordagem translacional da síndrome dos ovários policísticos; estudo das alterações endometriais na saúde reprodutiva feminina; aspectos moleculares e terapêuticos do câncer genital e mamário; marcadores bioquímicos, imunológicos e moleculares e sua relação com a endometriose peritoneal, de ovário e profunda.

Site oficial: http://limhc.fm.usp.br/portal/lim58-laboratorio-de-ginecologia-estrutural-e-molecular/

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Recent Submissions

  1. Linear and Nonlinear Heart Rate Variability Analysis in Gonadal Dysgenesis (Swyer Syndrome): A Case Report

    INTERNATIONAL JOURNAL OF CARDIOVASCULAR SCIENCES, v.34, n.4, p.486-489, 2021

    Abstract Swyer syndrome is one of the disorders of sexual differentiation. Previous studies have demonstrated increased sympathetic activity with heart rate variability (HRV) analysis with decreasing estradiol levels. One patient presented a pure 46, XY gonadal dysgenesis with female phenotype. C...

  2. Evaluation of guidelines on the use of vaginal mesh implants for pelvic organ prolapse using the AGREE II instrument

    INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS, v.154, n.3, p.400-411, 2021

    Objective To systematically evaluate the content and quality of national and international guidelines on vaginal mesh procedures for pelvic organ prolapse (POP). Methods We searched PubMed, Medline, Web of Science, and ScienceDirect from inception to March 2020 and organizations' websites. The qu...

  3. Laparoscopic sacrocolpopexy: A comprehensive literature review on current practice

    EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY, v.245, p.94-101, 2020

    Sacrocolpopexy is considered the preferred treatment for vaginal vault. However, numerous technical variants are being practiced. We aimed to summarize the recent literature in relation to technical aspects of laparoscopic sacrocolpopexy (LSC). We focused on surgical technique, mesh type, concomi...

  4. Contraceptive counseling during the pandemic: practical guidelines

    REVISTA BRASILEIRA DE GINECOLOGIA E OBSTETRICIA, v.43, n.7, p.579-584, 2021

  5. Everolimus plus anastrozole for female adnexal tumor of probable Wolffian origin (FATWO) with STK11 mutation

    GYNECOLOGIC ONCOLOGY REPORTS, v.37, article ID 100838, 5p, 2021

    Female adnexal tumor of probable Wolffian origin (FATWO) are a rare type of cancer that originates from Wolffian duct remnants. Due to its rarity, no standard systemic treatment is established for cases of recurrent or metastatic disease. Previous literature reported the use of platinum-based che...

  6. Role of systematic pelvic and para-aortic lymphadenectomy in delayed debulking surgery after six neoadjuvant chemotherapy cycles for high-grade serous ovarian carcinoma

    JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH, v.47, n.8, p.2737-2744, 2021

    Introduction We analyzed the role of systematic pelvic and para-aortic lymphadenectomy in delayed debulking surgery after six neoadjuvant chemotherapy (NACT) cycles for advanced high-grade serous ovarian carcinoma. Materials and Methods We retrospectively reviewed patients with advanced ovarian c...

  7. Systematic evaluation of endometriosis by transvaginal ultrasound can accurately replace diagnostic laparoscopy, mainly for deep and ovarian endometriosis

    HUMAN REPRODUCTION, v.36, n.6, p.1492-1500, 2021

    STUDY QUESTION: What is the sensitivity and the specificity of preoperative transvaginal ultrasound with bowel preparation (TVUS-BP) compared to diagnostic laparoscopy (DL) for the identification of ovarian and deep sites of endometriosis? SUMMARY ANSWER: DL was able to detect retrocervical, ovar...

  8. Association between sleep quality and depression among institutionalized and community older people-Brazilian Western Amazonia

    BMC PSYCHIATRY, v.21, n.1, article ID 367, 10p, 2021

    Background The transition in the population pyramid is a reality in several locations around the world and projections of an increase in the older population in Brazil demonstrate the relevance of studies on factors that may interfere in the functionality and quality of life in this age group. Th...

  9. Association of 2D and 3D transvaginal ultrasound findings with adenomyosis in symptomatic women of reproductive age: a prospective study

    CLINICS, v.76, article ID e2981, 8p, 2021

    OBJECTIVE: To evaluate the association of two-dimensional (2D) and three-dimensional (3D) transvaginal ultrasound (TVUS) findings with adenomyosis symptoms. METHODS: This prospective study conducted between January and December 2018 enrolled 78 women aged 18 to 40 years with abnormal uterine blee...

  10. Energy-based devices in gynecology: the new frontier for the treatment of genitourinary syndrome of postmenopause?

    CLINICS, v.76, article ID e3066, 2p, 2021