LIM/60 - Laboratório de Imunologia Clínica e Alergia
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Novos documentos depositados
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Data-driven, cross-disciplinary collaboration: lessons learned at the largest academic health center in Latin America during the COVID-19 pandemic
FRONTIERS IN PUBLIC HEALTH, v.12, article ID 1369129, 15p, 2024
Introduction The COVID-19 pandemic has prompted global research efforts to reduce infection impact, highlighting the potential of cross-disciplinary collaboration to enhance research quality and efficiency.Methods At the FMUSP-HC academic health system, we implemented innovative flow management r...
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ABX464 (obefazimod) for patients with COVID-19 at risk for severe disease: miR-AGE, a randomized, double-blind placebo-controlled trial
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY: GLOBAL, v.2, n.4, article ID 100140, p, 2023
Background: ABX464 (obefazimod) is a small molecule that upregulates a single microRNA (miR-124) in immune cells and reduces the production of various inflammatory cytokines and chemokines. Objective: We assessed the efficacy and safety of the standard of care (SoC) plus oral obefazimod (SoC plus...
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Rapid viral metagenomics using SMART-9N amplification and nanopore sequencing
WELLCOME OPEN RESEARCH, v.6, article ID 241, p, 2023
Emerging and re-emerging viruses are a global health concern. Genome sequencing as an approach for monitoring circulating viruses is currently hampered by complex and expensive methods. Untargeted, metagenomic nanopore sequencing can provide genomic information to identify pathogens, prepare for ...
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Recognition of Trypanosoma cruzi epitopes by IgG of benznidazole treated Chagas disease patients
BIOPHYSICAL REVIEWS, v.13, n.6, Special Issue, p.1432-1432, 2021
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Therapeutic neutralizing monoclonal antibody administration protects against lethal yellow fever infection
JOURNAL OF MEDICAL PRIMATOLOGY, v.52, n.5, Special Issue, p.338-338, 2023
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Occupational asthma and allergic asthma: differences in the physical activity level, clinical control, and airway inflammation
EUROPEAN RESPIRATORY JOURNAL, v.62, suppl.67, article ID PA953, 2p, 2023
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Characteristics and benefits of responders to a behavioral intervention to increase physical activity in asthma: preliminary data from a pragmatic study
EUROPEAN RESPIRATORY JOURNAL, v.62, suppl.67, article ID PA352, 3p, 2023
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Parasite DNA and Markers of Decreased Immune Activation Associate Prospectively with Cardiac Functional Decline over 10 Years among <i>Trypanosoma cruzi</i> Seropositive Individuals in Brazil
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, v.25, n.1, article ID 44, 9p, 2024
Parasitemia and inflammatory markers are cross-sectionally associated with chronic Chagas cardiomyopathy (CCC) among patients with Trypanosoma cruzi. However, the prospective association of the parasite load and host immune response-related characteristics with CCC (that is, progressors) among T....
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Encephalopathy Caused by Human Parvovirus B19 Genotype 1 Associated with <i>Haemophilus influenzae</i> Meningitis in a Newborn
CURRENT ISSUES IN MOLECULAR BIOLOGY, v.45, n.9, p.6958-6966, 2023
Parvovirus B19 infection is associated with a wide range of clinical manifestations, from asymptomatic to severe neurological disorders. Its major clinical symptoms, fever and rash, are common to multiple viruses, and laboratory tests to detect B19 are frequently not available. Thus, the impact o...
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HIV-1 Remission: Accelerating the Path to Permanent HIV-1 Silencing
VIRUSES-BASEL, v.15, n.11, article ID 2171, 11p, 2023
Despite remarkable progress, a cure for HIV-1 infection remains elusive. Rebound competent latent and transcriptionally active reservoir cells persevere despite antiretroviral therapy and rekindle infection due to inefficient proviral silencing. We propose a novel ""block-lock-stop"" approach, en...
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