LIM/62 - Laboratório de Investigação Médica em Neurocirurgia

O Laboratório de Investigação Médica em Neurocirurgia é ligado ao Departamento Departamento de Neurologia da Faculdade de Medicina da Universidade de São Paulo (FMUSP). Denominado Laboratório de Fisiopatologia Cirúrgica e ligado ao Departamento Fisiopatologia Cirúrgica até o ano de 2019 com produção científica até o ano de 2018.

Linhas de pesquisa: medicina, com ênfase em neurocirurgia e atua principalmente nos seguintes temas: dor, dor aguda, dor crônica, dor neuropática e síndrome dolorosa miofascial, neurocirurgia, cirurgia para movimentos anormais, espasticidade, doenças da coluna vertebral e tumores do sistema nervoso; validação psicométrica e tradução de instrumentos de rastreio e caracterização de síndromes dolorosas e seus aspectos; excitabilidade cortical em doentes com dor crônica, uso de neuromodulação não invasiva em dor; profilaxia de dor neuropática em doentes com câncer; uso de neuromodulação implantada em dor; dor na doença de Parkinson; hipertensão intracraniana e lesão encefálica; neurotrauma; neuromodulação não invasiva em pacientes e técnicas neurocirúrgicas.

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Recent Submissions


    CRITICAL CARE MEDICINE, v.50, n.1, suppl.S, p.413-413, 2022

  2. CoaguChek (R) XS versus standard laboratory prothrombin time for anticoagulant monitoring in patients with antiphospholipid syndrome

    LUPUS, v.31, n.5, p.565-574, 2022

    Introduction: The standard of care for thrombotic antiphospholipid syndrome (APS) is anticoagulation with vitamin K antagonists (VKAs). Prothrombin time, and its corresponding international normalized ratio (INR), is the laboratory test routinely performed to assess anticoagulation. Self-manageme...

  3. Guidelines for Parkinson's disease treatment consensus from the Movement Disorders Scientific Department of the Brazilian Academy of Neurology- motor symptoms

    ARQUIVOS DE NEURO-PSIQUIATRIA, v.80, n.3, p.316-329, 2022

    The treatment of Parkinson's disease (PD) is challenging, especially since it is considered highly individualized. The Brazilian Academy of Neurology has recognized the need to disseminate knowledge about the management of PD treatment, adapting the best evidence to the Brazilian reality. Thus, t...

  4. Assessing the burden of osteoarthritis in Latin America: a rapid evidence assessment

    CLINICAL RHEUMATOLOGY, v.41, n.5, p.1285-1292, 2022

    This rapid evidence assessment (REA) was conducted to explore the burden of weight-bearing joint osteoarthritis in the developing countries of Latin America. REA methodology used a standardized search strategy to identify observational studies published from 2010 to 23 April 2020 that reported ou...

  5. New updates on transcranial magnetic stimulation in chronic pain


    Purpose of review Chronic pain is the most prevalent symptomatic disease worldwide. Nonpharmacological interventions, such as noninvasive neuromodulation (NIN), have gained scientific evidence to support their use as an add-on strategy to pharmacological pain management. The most studied NIN tech...

  6. A systematic review and meta-analysis of fusion rate enhancements and bone graft options for spine surgery

    SCIENTIFIC REPORTS, v.12, n.1, article ID 7546, 9p, 2022

    Our study aimed to evaluate differences in outcomes of patients submitted to spinal fusion using different grafts measuring the effectiveness of spinal fusion rates, pseudarthrosis rates, and adverse events. Applying the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement...

  7. The diagnostic accuracy of MRI in determining the relations between paraclinoid aneurysms and the cavernous sinus

    NEURORADIOLOGY, v.64, n.6, p.1175-1185, 2022

    Purpose The location of paraclinoid aneurysms is determinant for evaluation of its intradural compartment and risk of SAH after rupture. Advanced MRI techniques have provided clear visualization of the distal dural ring (DDR) to determine whether an aneurysm is intracavernous, transitional or int...

  8. Could outcomes of intracranial aneurysms be better predict using serum creatinine and glomerular filtration rate?

    ACTA CIRURGICA BRASILEIRA, v.37, n.1, article ID e370107, 11p, 2022

    Purpose: To analyze the role of serum creatinine levels as a biomarker of intracranial aneurysm outcomes. Methods: This is a prospective analysis of outcomes of patients with intracranial aneurysm. One hundred forty-seven patients with serum creatinine at admission and 6 months follow up were inc...

  9. Sensory characteristics and chronic facial pain conditions: Cross-sectional study

    ARCHIVES OF ORAL BIOLOGY, v.135, article ID 105361, 7p, 2022

    Objectives: This study investigated patients with neuropathic, myofascial and other orofacial pain conditions according to the differences and similarities of the sensory profile, and the association between sensory findings and neuropathic or non-neuropathic conditions.Design: 132 healthy contro...

  10. Microsurgical approaches to the pulvinar: A comparative analysis

    JOURNAL OF CLINICAL NEUROSCIENCE, v.99, p.233-238, 2022

    Objective: To compare the area of exposure to the cisternal thalamus associated with four surgical techniques: supracerebellar-infratentorial (SCIT), occipital interhemispheric (OI), transchoroidal (TC) and subtemporal before and after parahippocampal resection (ST and STh, respectively). Methods...