LIM/62 - Laboratório de Investigação Médica em Neurocirurgia

O Laboratório de Investigação Médica em Neurocirurgia é ligado ao Departamento Departamento de Neurologia da Faculdade de Medicina da Universidade de São Paulo (FMUSP). Denominado Laboratório de Fisiopatologia Cirúrgica e ligado ao Departamento Fisiopatologia Cirúrgica até o ano de 2019 com produção científica até o ano de 2018.

Linhas de pesquisa: medicina, com ênfase em neurocirurgia e atua principalmente nos seguintes temas: dor, dor aguda, dor crônica, dor neuropática e síndrome dolorosa miofascial, neurocirurgia, cirurgia para movimentos anormais, espasticidade, doenças da coluna vertebral e tumores do sistema nervoso; validação psicométrica e tradução de instrumentos de rastreio e caracterização de síndromes dolorosas e seus aspectos; excitabilidade cortical em doentes com dor crônica, uso de neuromodulação não invasiva em dor; profilaxia de dor neuropática em doentes com câncer; uso de neuromodulação implantada em dor; dor na doença de Parkinson; hipertensão intracraniana e lesão encefálica; neurotrauma; neuromodulação não invasiva em pacientes e técnicas neurocirúrgicas.

Site oficial: http://limhc.fm.usp.br/portal/lim62-laboratorio-de-fisiopatologia-cirurgica/

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Recent Submissions

  1. Effect of photobiomodulation on neuropathic pain of diabetic origin: a narrative review of the literature

    LASERS IN MEDICAL SCIENCE, v.38, n.1, article ID 244, 21p, 2023

    To update the literature on the effectiveness of photobiomodulation (PBM) therapy in relieving pain in patients with diabetic peripheral neuropathy (DPN) compared to the effects of post-intervention, control/placebo groups, and other therapies. Search on the following databases: PORTAL PERIODICOS...

  2. Location of Trigger Points in a Group of Police Working Dogs: A Preliminary Study

    ANIMALS, v.13, n.18, article ID 2836, 11p, 2023

    Simple Summary This research looked at the number and position of sore points in police working dogs. The study selected twelve dogs from a military police kennel based on convenience. Only dogs that were active, had no other health issues or changes seen in X-rays, and were involved in six hours...

  3. E.L., a modern-day Phineas Gage: Revisiting frontal lobe injury

    LANCET REGIONAL HEALTH-AMERICAS, v.14, article ID 100340, 17p, 2022

    Background How the prefrontal cortex (PFC) recovers its functionality following lesions remains a conundrum. Recent work has uncovered the importance of transient low-frequency oscillatory activity (LFO; < 4 Hz) for the recovery of an injured brain. We aimed to determine whether persistent cortic...

  4. Enhancing meningioma resection: a comprehensive study on the safety and effectiveness of Onyx™ presurgical embolization

    NEUROSURGICAL REVIEW, v.46, n.1, article ID 299, 11p, 2023

    Presurgical embolization (PE) has emerged as an interesting strategy to help turn brain tumor resection more amenable. This study aims to systematically review the safety and effectiveness of Onyx (TM) PE in meningioma resection. We followed Cochrane Collaboration and PRISMA for systematic review...

  5. Pain in Parkinson disease: mechanistic substrates, main classification systems, and how to make sense out of them

    PAIN, v.164, n.11, p.2425-2434, 2023

    Parkinson disease (PD) affects up to 2% of the general population older than 65 years and is a major cause of functional loss. Chronic pain is a common nonmotor symptom that affects up to 80% of patients with (Pw) PD both in prodromal phases and during the subsequent stages of the disease, negati...

  6. Elevated salivary copper concentration in patients with Wilson's disease

    PARKINSONISM & RELATED DISORDERS, v.116, article ID 105893, 3p, 2023

  7. Doing More with Less on Intracranial Pressure Monitoring

    WORLD NEUROSURGERY, v.178, p.93-95, 2023

    BACKGROUND: Intracranial pressure (ICP) management based on predetermined thresholds is not accurate in light of recent research on cerebrovascular physiology. Interpersonal and intrapersonal variations will lead ICP elevations to reach individualized thresholds for intracranial compliance impair...

  8. Point-Counterpoint: Cerebral perfusion pressure is a high-risk concept

    JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, v.43, n.11, p.2008-2010, 2023

    Cerebral perfusion pressure (CPP) is calculated as the difference between mean arterial blood pressure and mean intracranial pressure, being commonly applied in neurocritical care. This commentary discusses recent physiological advances in knowledge as well as bedside practice issues that in comb...

  9. Is transcranial direct current stimulation (tDCS) effective to improve cognition and functionality after severe traumatic brain injury? A perspective article and hypothesis

    FRONTIERS IN HUMAN NEUROSCIENCE, v.17, article ID 1162854, 8p, 2023

    Severe traumatic brain injury (sTBI) is an important cause of disability and mortality and affects people of all ages. Current scientific evidence indicates that motor dysfunction and cognitive impairment are the main limiting factors in patients with sTBI. Transcranial direct current stimulation...

  10. Axial Postural Abnormalities in Parkinsonism: Gaps in Predictors, Pathophysiology, and Management

    MOVEMENT DISORDERS, v.38, n.5, p.732-739, 2023