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DC Field | Value | Language |
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dc.contributor | Sistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP | |
dc.contributor.author | BORTOLOTTO, Alexandre L. | |
dc.contributor.author | VERRIER, Richard L. | |
dc.contributor.author | NEARING, Bruce D. | |
dc.contributor.author | MARUM, Alexandre A. | |
dc.contributor.author | SILVA, Bruna Araujo | |
dc.contributor.author | PEDREIRA, Giovanna C. | |
dc.contributor.author | SILVA, Fernanda Tessarolo | |
dc.contributor.author | MEDEIROS, Sofia A. | |
dc.contributor.author | SROUBEK, Jakub | |
dc.contributor.author | ZIMETBAUM, Peter J. | |
dc.contributor.author | CHANG, James D. | |
dc.date.accessioned | 2020-12-16T14:56:11Z | - |
dc.date.available | 2020-12-16T14:56:11Z | - |
dc.date.issued | 2020 | |
dc.identifier.citation | HEART RHYTHM, v.17, n.11, p.1887-1896, 2020 | |
dc.identifier.issn | 1547-5271 | |
dc.identifier.uri | https://observatorio.fm.usp.br/handle/OPI/38500 | - |
dc.description.abstract | BACKGROUND Reliable quantitative preimplantation predictors of response to cardiac resynchronization therapy (CRT) are needed. OBJECTIVE We tested the utility of preimplantation R-wave and T-wave heterogeneity (RWH and TWH, respectively) compared to standard QRS complex duration in identifying mechanical super-responders to CRT and mortality risk. METHODS We analyzed resting 12-lead electrocardiographic recordings from all 155 patients who received CRT devices between 2006 and 2018 at our institution and met class I and IIA American College of Cardiology/American Heart Association/Heart Rhythm Society guidelines with echocardiograms before and after implantation. Super-responders (n=35, 23%) had >= 20% increase in left ventricular ejection fraction and/or >= 20% decrease in left ventricular end-systolic diameter and were compared with non-super-responders (n=120, 77%), who did not meet these criteria. RWH and TWH were measured using second central moment analysis. RESULTS Among patients with non-left bundle branch block (LBBB), preimplantation RWH was significantly lower in super-responders than in non-super-responders in 3 of 4 lead sets ( P=.001 to P=.038) and TWH in 2 lead sets (both, P=.05), with the corresponding areas under the curve (RWH: 0.810-0.891, P<.001; TWH: 0.759-0.810, P <=.005). No differences were observed in the LBBB group. Preimplantation QRS complex duration also did not differ between super-responders and non-super-responders among patients with ( P=.856) or without ( P=.724) LBBB; the areas under the curve were nonsignificant (both, P=.69). RWH V1-3LILII >= 420 mu V predicted 3-year all-cause mortality in the entire cohort ( P=.037), with a hazard ratio of 7.440 (95% confidence interval 1.015-54.527; P=.048); QRS complex duration >= 150 ms did not predict mortality ( P=.27). CONCLUSION Preimplantation interlead electrocardiographic heterogeneity but not QRS complex duration predicts mechanical super-response to CRT in patients with non-LBBB. | eng |
dc.language.iso | eng | |
dc.publisher | ELSEVIER SCIENCE INC | eng |
dc.relation.ispartof | Heart Rhythm | |
dc.rights | restrictedAccess | eng |
dc.subject | Cardiac resynchronization therapy | eng |
dc.subject | Heart failure | eng |
dc.subject | Preimplantation | eng |
dc.subject | R-wave heterogeneity | eng |
dc.subject | Survival | eng |
dc.subject | Super-response | eng |
dc.subject | T-wave heterogeneity | eng |
dc.subject.other | t-wave morphology | eng |
dc.subject.other | ventricular repolarization | eng |
dc.subject.other | transmural dispersion | eng |
dc.subject.other | qt interval | eng |
dc.subject.other | parameters | eng |
dc.subject.other | death | eng |
dc.subject.other | risk | eng |
dc.title | Preimplantation interlead ECG heterogeneity is superior to QRS complex duration in predicting mechanical super-response in patients with non-left bundle branch block receiving cardiac resynchronization therapy | eng |
dc.type | article | eng |
dc.rights.holder | Copyright ELSEVIER SCIENCE INC | eng |
dc.identifier.doi | 10.1016/j.hrthm.2020.05.036 | |
dc.identifier.pmid | 32497764 | |
dc.subject.wos | Cardiac & Cardiovascular Systems | eng |
dc.type.category | original article | eng |
dc.type.version | publishedVersion | eng |
hcfmusp.author.external | VERRIER, Richard L.:Beth Israel Deaconess Med Ctr, Dept Med, Boston, MA 02215 USA; Harvard Med Sch, Boston, MA 02115 USA | |
hcfmusp.author.external | NEARING, Bruce D.:Beth Israel Deaconess Med Ctr, Dept Med, Boston, MA 02215 USA; Harvard Med Sch, Boston, MA 02115 USA | |
hcfmusp.author.external | SROUBEK, Jakub:Beth Israel Deaconess Med Ctr, Dept Med, Boston, MA 02215 USA; Harvard Med Sch, Boston, MA 02115 USA | |
hcfmusp.author.external | ZIMETBAUM, Peter J.:Beth Israel Deaconess Med Ctr, Dept Med, Boston, MA 02215 USA; Harvard Med Sch, Boston, MA 02115 USA | |
hcfmusp.author.external | CHANG, James D.:Beth Israel Deaconess Med Ctr, Dept Med, Boston, MA 02215 USA; Harvard Med Sch, Boston, MA 02115 USA | |
hcfmusp.description.beginpage | 1887 | |
hcfmusp.description.endpage | 1896 | |
hcfmusp.description.issue | 11 | |
hcfmusp.description.volume | 17 | |
hcfmusp.origem | WOS | |
hcfmusp.origem.id | WOS:000583293800008 | |
hcfmusp.origem.id | 2-s2.0-85089015463 | |
hcfmusp.publisher.city | NEW YORK | eng |
hcfmusp.publisher.country | USA | eng |
hcfmusp.relation.reference | Berger T, 2005, J CARDIOVASC ELECTR, V16, P611, DOI 10.1046/j.1540-8167.2005.40496.x | eng |
hcfmusp.relation.reference | Burke GM, 2018, CIRCULATION, V138 | eng |
hcfmusp.relation.reference | Cvijic M, 2018, HEART RHYTHM, V15, P1784, DOI 10.1016/j.hrthm.2018.06.023 | eng |
hcfmusp.relation.reference | Daubert JC, 2012, HEART RHYTHM, V9, P1524, DOI 10.1016/j.hrthm.2012.07.025 | eng |
hcfmusp.relation.reference | Dupont M, 2012, J AM COLL CARDIOL, V60, P592, DOI 10.1016/j.jacc.2012.03.059 | eng |
hcfmusp.relation.reference | Fish JM, 2004, CIRCULATION, V109, P2136, DOI 10.1161/01.CIR.0000127423.75608.A4 | eng |
hcfmusp.relation.reference | Henin M, 2020, CARDIOL RES, V11, P1, DOI 10.14740/cr989 | eng |
hcfmusp.relation.reference | Itoh M, 2013, EUROPACE, V15, P1798, DOI 10.1093/europace/eut145 | eng |
hcfmusp.relation.reference | Kentta TV, 2016, HEART RHYTHM, V13, P713, DOI 10.1016/j.hrthm.2015.11.035 | eng |
hcfmusp.relation.reference | Lellouche N, 2007, HEART RHYTHM, V4, P1274, DOI 10.1016/j.hrthm.2007.06.012 | eng |
hcfmusp.relation.reference | Medina-Ravell VA, 2003, CIRCULATION, V107, P740, DOI 10.1161/01.CIR.0000048126.07819.37 | eng |
hcfmusp.relation.reference | Moss AJ, 2009, NEW ENGL J MED, V361, P1329, DOI 10.1056/NEJMoa0906431 | eng |
hcfmusp.relation.reference | Nearing BD, 2003, J APPL PHYSIOL, V95, P2265, DOI 10.1152/japplphysiol.00623.2003 | eng |
hcfmusp.relation.reference | Porthan K, 2013, CIRC-ARRHYTHMIA ELEC, V6, P690, DOI 10.1161/CIRCEP.113.000356 | eng |
hcfmusp.relation.reference | Rickard J, 2011, AM J CARDIOL, V108, P1576, DOI 10.1016/j.amjcard.2011.07.017 | eng |
hcfmusp.relation.reference | Rickard J, 2010, HEART RHYTHM, V7, P885, DOI 10.1016/j.hrthm.2010.04.005 | eng |
hcfmusp.relation.reference | Singh JP, 2018, ESC HEART FAIL, V5, P1184, DOI 10.1002/ehf2.12340 | eng |
hcfmusp.relation.reference | Stephansen C, 2019, ANN NONINVAS ELECTRO, V24, DOI 10.1111/anec.12621 | eng |
hcfmusp.relation.reference | Strauss DG, 2011, AM J CARDIOL, V107, P927, DOI 10.1016/j.amjcard.2010.11.010 | eng |
hcfmusp.relation.reference | Tan AY, 2017, J CARDIOVASC ELECTR, V28, P1324, DOI 10.1111/jce.13288 | eng |
hcfmusp.relation.reference | Tomassoni G, 2016, J INNOV CARD RHYTHM, V7, P51 | eng |
hcfmusp.relation.reference | Varma N, 2009, AM J CARDIOL, V103, P1578, DOI 10.1016/j.amjcard.2009.01.379 | eng |
hcfmusp.relation.reference | Verrier RL, 2017, HEART RHYTHM, V14, P1466, DOI 10.1016/j.hrthm.2017.06.017 | eng |
hcfmusp.relation.reference | Wakayama Y, 2005, CIRC RES, V96, P1266, DOI 10.1161/01.RES.0000172544.56818.54 | eng |
dc.description.index | MEDLINE | eng |
dc.identifier.eissn | 1556-3871 | |
hcfmusp.citation.scopus | 6 | - |
hcfmusp.scopus.lastupdate | 2024-03-29 | - |
Appears in Collections: | Artigos e Materiais de Revistas Científicas - FM/Outros Artigos e Materiais de Revistas Científicas - LIM/04 Artigos e Materiais de Revistas Científicas - LIM/11 Artigos e Materiais de Revistas Científicas - ODS/03 |
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