Departamento de Neurologia - FM/MNE
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The diagnostic accuracy of MRI in determining the relations between paraclinoid aneurysms and the cavernous sinus
NEURORADIOLOGY, v.64, n.6, p.1175-1185, 2022
Purpose The location of paraclinoid aneurysms is determinant for evaluation of its intradural compartment and risk of SAH after rupture. Advanced MRI techniques have provided clear visualization of the distal dural ring (DDR) to determine whether an aneurysm is intracavernous, transitional or int...
A systematic review and meta-analysis of fusion rate enhancements and bone graft options for spine surgery
SCIENTIFIC REPORTS, v.12, n.1, article ID 7546, 9p, 2022
Our study aimed to evaluate differences in outcomes of patients submitted to spinal fusion using different grafts measuring the effectiveness of spinal fusion rates, pseudarthrosis rates, and adverse events. Applying the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement...
Sensory characteristics and chronic facial pain conditions: Cross-sectional study
ARCHIVES OF ORAL BIOLOGY, v.135, article ID 105361, 7p, 2022
Objectives: This study investigated patients with neuropathic, myofascial and other orofacial pain conditions according to the differences and similarities of the sensory profile, and the association between sensory findings and neuropathic or non-neuropathic conditions.Design: 132 healthy contro...
Could outcomes of intracranial aneurysms be better predict using serum creatinine and glomerular filtration rate?
ACTA CIRURGICA BRASILEIRA, v.37, n.1, article ID e370107, 11p, 2022
Purpose: To analyze the role of serum creatinine levels as a biomarker of intracranial aneurysm outcomes. Methods: This is a prospective analysis of outcomes of patients with intracranial aneurysm. One hundred forty-seven patients with serum creatinine at admission and 6 months follow up were inc...
Extreme Clinical Variability Among Carriers of Pathogenic Variant in SSBP1
MOVEMENT DISORDERS, v.37, n.4, p.879-881, 2022
Distribution of leptin receptors in the brain stem: possible route in the pathophysiology of neuromuscular control of airway resistance during sleep
SLEEP MEDICINE, v.93, p.56-62, 2022
Introduction: Leptin, a hormone related to satiety, has been studied because of its association with obesity and sleep apnea. The distribution of leptin receptors in the brain stem, and in the hypoglossal nucleus, has not yet been described. The stimulation of these muscles has been studied in th...
Microsurgical approaches to the pulvinar: A comparative analysis
JOURNAL OF CLINICAL NEUROSCIENCE, v.99, p.233-238, 2022
Objective: To compare the area of exposure to the cisternal thalamus associated with four surgical techniques: supracerebellar-infratentorial (SCIT), occipital interhemispheric (OI), transchoroidal (TC) and subtemporal before and after parahippocampal resection (ST and STh, respectively). Methods...
Incidental magnetic resonance imaging findings leading to an unusual diagnosis: Adult onset Krabbe disease
EUROPEAN JOURNAL OF NEUROLOGY, v.29, n.6, p.1859-1862, 2022
Background and purpose Krabbe disease (KD), or globoid cell leukodystrophy (Online Mendelian Inheritance in Man #245200), is an autosomal recessive lysosomal storage disease caused by mutations in GALC leading to galactocerebrosidase deficiency. Age at onset can vary from early infancy (3-6 month...
Cellular Model of Malignant Transformation of Primary Human Astrocytes Induced by Deadhesion/Readhesion Cycles
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, v.23, n.9, article ID 4471, 18p, 2022
Astrocytoma is the most common and aggressive tumor of the central nervous system. Genetic and environmental factors, bacterial infection, and several other factors are known to be involved in gliomagenesis, although the complete underlying molecular mechanism is not fully understood. Tumorigenes...
Focused goodness of fit tests for gene set analyses
BRIEFINGS IN BIOINFORMATICS, v.23, n.1, article ID bbab472, 10p, 2022
Gene set-based signal detection analyses are used to detect an association between a trait and a set of genes by accumulating signals across the genes in the gene set. Since signal detection is concerned with identifying whether any of the genes in the gene set are non-null, a goodness-of-fit (GO...