The Multi-Partner Consortium to Expand Dementia Research in Latin America (ReDLat): Driving Multicentric Research and Implementation Science

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dc.contributor Sistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.author IBANEZ, Agustin
YOKOYAMA, Jennifer S.
POSSIN, Katherine L.
MATALLANA, Diana
LOPERA, Francisco
NITRINI, Ricardo FMUSP-HC
TAKADA, Leonel T. FMUSP-HC
CUSTODIO, Nilton
ORTIZ, Ana Luisa Sosa
AVILA-FUNES, Jose Alberto
BEHRENS, Maria Isabel
SLACHEVSKY, Andrea
MYERS, Richard M.
COCHRAN, J. Nicholas
BRUSCO, Luis Ignacio
BRUNO, Martin A.
BRUCKI, Sonia M. D. FMUSP-HC
PINA-ESCUDERO, Stefanie Danielle
OLIVEIRA, Maira Okada de FMUSP-HC
KEHOE, Patricio Donnelly
GARCIA, Adolfo M.
CARDONA, Juan Felipe
SANTAMARIA-GARCIA, Hernando
MOGUILNER, Sebastian
DURAN-ANIOTZ, Claudia
TAGLIAZUCCHI, Enzo
MAITO, Marcelo
IBARROLA, Erika Mariana Longoria
PINTADO-CAIPA, Maritza
GODOY, Maria Eugenia
BAKMAN, Vera
JAVANDEL, Shireen
KOSIK, Kenneth S.
VALCOUR, Victor
MILLER, Bruce L.
dc.date.issued 2021
dc.identifier.citation FRONTIERS IN NEUROLOGY, v.12, article ID 631722, 16p, 2021
dc.identifier.issn 1664-2295
dc.identifier.uri https://observatorio.fm.usp.br/handle/OPI/39901
dc.description.abstract Dementia is becoming increasingly prevalent in Latin America, contrasting with stable or declining rates in North America and Europe. This scenario places unprecedented clinical, social, and economic burden upon patients, families, and health systems. The challenges prove particularly pressing for conditions with highly specific diagnostic and management demands, such as frontotemporal dementia. Here we introduce a research and networking initiative designed to tackle these ensuing hurdles, the Multi-partner consortium to expand dementia research in Latin America (ReDLat). First, we present ReDLat's regional research framework, aimed at identifying the unique genetic, social, and economic factors driving the presentation of frontotemporal dementia and Alzheimer's disease in Latin America relative to the US. We describe ongoing ReDLat studies in various fields and ongoing research extensions. Then, we introduce actions coordinated by ReDLat and the Latin America and Caribbean Consortium on Dementia (LAC-CD) to develop culturally appropriate diagnostic tools, regional visibility and capacity building, diplomatic coordination in local priority areas, and a knowledge-to-action framework toward a regional action plan. Together, these research and networking initiatives will help to establish strong cross-national bonds, support the implementation of regional dementia plans, enhance health systems' infrastructure, and increase translational research collaborations across the continent.
dc.description.sponsorship · Multi-partner Consortium to Expand Dementia Research in Latin America [ReDLat, by National Institutes of Health, National Institutes of Aging] [R01 AG057234]
· Multi-partner Consortium to Expand Dementia Research in Latin America [Alzheimer's Association] [SG-20-725707]
· Multi-partner Consortium to Expand Dementia Research in Latin America [Rainwater Charitable Fundation-Tau]
· Multi-partner Consortium to Expand Dementia Research in Latin America [Global Brain Health Institute]
· TakedaTakeda Pharmaceutical Company Ltd [CW2680521]
· Alzheimer's AssociationAlzheimer's Association [GBHI ALZ UK-20-639295]
· CONICETConsejo Nacional de Investigaciones Cientificas y Tecnicas (CONICET) [ANID/FONDAP/15150012]
· Sistema General de Regalias [BPIN2018000100059]
· Universidad del valle [CI 5316]
· Inter-American Development Bank (IDB)
· ANID/FONDEF [ID20I10152]
· [2018-AARG-591107]
dc.language.iso eng
dc.publisher FRONTIERS MEDIA SA
dc.relation.ispartof Frontiers in Neurology
dc.rights openAccess
dc.subject dementia; fronto-temporal dementia; SES; SDOH; genetics; Alzheimer' s disease; implementation science; Latin America
dc.title The Multi-Partner Consortium to Expand Dementia Research in Latin America (ReDLat): Driving Multicentric Research and Implementation Science
dc.type article
dc.rights.holder Copyright FRONTIERS MEDIA SA
dc.contributor.groupauthor Latin Amer Caribbean Consortium De
dc.description.group LIM/15
dc.description.group LIM/45
dc.identifier.doi 10.3389/fneur.2021.631722
dc.identifier.pmid 33776890
dc.type.category review
dc.type.version publishedVersion
hcfmusp.author NITRINI, Ricardo:FM:MNE
hcfmusp.author TAKADA, Leonel T.:HC:ICHC
hcfmusp.author BRUCKI, Sonia M. D.:HC:ICHC
hcfmusp.author OLIVEIRA, Maira Okada de:FM:
hcfmusp.author.external · IBANEZ, Agustin:Univ Calif San Francisco, Global Brain Hlth Inst GBHI, San Francisco, CA 94143 USA; Trinity Coll Dublin, Global Brain Hlth Inst GBHI, Dublin, Ireland; Univ San Andres, Cognit Neurosci Ctr, Buenos Aires, DF, Argentina; Natl Sci & Tech Res Council CONICET, Buenos Aires, DF, Argentina; Adolfo Ibanez Univ, Univ Adolfo Ibanez, Ctr Social & Cognit Neurosci, Latin Amer Inst Brain Hlth BrainLat,Sch Psychol, Santiago, Chile
· YOKOYAMA, Jennifer S.:Univ Calif San Francisco, Global Brain Hlth Inst GBHI, San Francisco, CA 94143 USA; Trinity Coll Dublin, Global Brain Hlth Inst GBHI, Dublin, Ireland; Univ Calif San Francisco, Dept Neurol, Memory & Aging Ctr, San Francisco, CA 94143 USA; Univ Calif San Francisco, Dept Radiol & Biomed Imaging, San Francisco, CA 94143 USA
· POSSIN, Katherine L.:Univ Calif San Francisco, Global Brain Hlth Inst GBHI, San Francisco, CA 94143 USA; Trinity Coll Dublin, Global Brain Hlth Inst GBHI, Dublin, Ireland; Univ Calif San Francisco, Dept Neurol, Memory & Aging Ctr, San Francisco, CA 94143 USA
· MATALLANA, Diana:Pontificia Univ Javeriana, Aging Inst, Sch Med, Psychiat Dept, Bogota, Colombia; Hosp Univ San Ignacio, Memory & Cognit Clin, Intellectus, Bogota, Colombia; Hosp Univ Santa Fe Bogota, Mental Hlth Unit, Bogota, Colombia
· LOPERA, Francisco:Univ Antioquia, Grp Neurociencias Antioquia, Medellin, Colombia
· CUSTODIO, Nilton:Peruvian Inst Neurosci, Unit Cognit Impairment & Dementia Prevent, Cognit Neurol Ctr, Lima, Peru
· ORTIZ, Ana Luisa Sosa:Univ Nacl Autonoma Mexico, Inst Nacl Neurol & Neurocirugia MVS, Mexico City, DF, Mexico
· AVILA-FUNES, Jose Alberto:Inst Nacl Ciencias Med & Nutr Salvador Zubiran, Dept Geriatr, Mexico City, DF, Mexico; Univ Bordeaux, Bordeaux Populat Hlth Res Ctr, INSERM, Bordeaux, France
· BEHRENS, Maria Isabel:Univ Chile, Hosp Clin, Ctr Invest Clin Avanzada, Fa Med, Santiago, Chile; Hosp Clinico Univ Chile, Dept Neurol & Neurocirugia, Santiago, Chile; Univ Chile, Dept Neurociencia, Fac Medicina, Santiago, Chile; Univ Desarrollo, Clin Alemana Santiago, Santiago, Chile
· SLACHEVSKY, Andrea:Univ Desarrollo, Clin Alemana Santiago, Santiago, Chile; Gerosci Ctr Brain Hlth & Metab GERO, Santiago, Chile; Inst Biomed Sci Neurosci & East Neurosci, Physiopathol Dept, Neuropsychol & Clin Neurosci Lab, Santiago, Chile; Univ Chile, Fac Med, Santiago, Chile; Univ Chile, Hosp Salvador, Memory & Neuropsychiat Clin CMYN, Fac Med,Neurol Dept, Santiago, Chile
· MYERS, Richard M.:Hudson Alpha Inst Biotechnol, Huntsville, AL USA
· COCHRAN, J. Nicholas:Hudson Alpha Inst Biotechnol, Huntsville, AL USA
· BRUSCO, Luis Ignacio:Univ Buenos Aires, Fac Med, Buenos Aires, DF, Argentina; ALZAR Alzheimer, Buenos Aires, DF, Argentina
· BRUNO, Martin A.:Natl Sci & Tech Res Council CONICET, Buenos Aires, DF, Argentina; Univ Catolica Cuyo, Inst Ciencias Biomed, Fac Ciencias Med, San Juan, Argentina
· PINA-ESCUDERO, Stefanie Danielle:Univ Calif San Francisco, Global Brain Hlth Inst GBHI, San Francisco, CA 94143 USA; Trinity Coll Dublin, Global Brain Hlth Inst GBHI, Dublin, Ireland; Univ Calif San Francisco, Dept Neurol, Memory & Aging Ctr, San Francisco, CA 94143 USA
· KEHOE, Patricio Donnelly:Natl Sci & Tech Res Council CONICET, Buenos Aires, DF, Argentina; French Argentine Int Ctr Informat & Syst Sci, Multimedia Signal Proc Grp, Neuroimage Div, Rosario, Argentina
· GARCIA, Adolfo M.:Univ Calif San Francisco, Global Brain Hlth Inst GBHI, San Francisco, CA 94143 USA; Trinity Coll Dublin, Global Brain Hlth Inst GBHI, Dublin, Ireland; Univ San Andres, Cognit Neurosci Ctr, Buenos Aires, DF, Argentina; Natl Sci & Tech Res Council CONICET, Buenos Aires, DF, Argentina; Natl Univ Cuyo, Fac Educ, Mendoza, Argentina
· CARDONA, Juan Felipe:Univ Valle, Cali, Colombia
· SANTAMARIA-GARCIA, Hernando:Hosp Univ San Ignacio, Memory & Cognit Clin, Intellectus, Bogota, Colombia; Pontificia Univ Javeriana, Dept Psychiat, PhD Program Neurosci, Physiol, Bogota, Colombia
· MOGUILNER, Sebastian:Univ Calif San Francisco, Global Brain Hlth Inst GBHI, San Francisco, CA 94143 USA; Trinity Coll Dublin, Global Brain Hlth Inst GBHI, Dublin, Ireland
· DURAN-ANIOTZ, Claudia:Adolfo Ibanez Univ, Univ Adolfo Ibanez, Ctr Social & Cognit Neurosci, Latin Amer Inst Brain Hlth BrainLat,Sch Psychol, Santiago, Chile
· TAGLIAZUCCHI, Enzo:Univ Buenos Aires, Fac Ciencias Exactas & Nat, Dept Fis, Buenos Aires, DF, Argentina
· MAITO, Marcelo:Univ San Andres, Cognit Neurosci Ctr, Buenos Aires, DF, Argentina
· IBARROLA, Erika Mariana Longoria:Inst Nacl Ciencias Med & Nutr Salvador Zubiran, Dept Geriatr, Mexico City, DF, Mexico
· PINTADO-CAIPA, Maritza:Univ Calif San Francisco, Global Brain Hlth Inst GBHI, San Francisco, CA 94143 USA; Trinity Coll Dublin, Global Brain Hlth Inst GBHI, Dublin, Ireland; Peruvian Inst Neurosci, Unit Cognit Impairment & Dementia Prevent, Cognit Neurol Ctr, Lima, Peru
· GODOY, Maria Eugenia:Univ San Andres, Cognit Neurosci Ctr, Buenos Aires, DF, Argentina
· BAKMAN, Vera:Univ Calif San Francisco, Global Brain Hlth Inst GBHI, San Francisco, CA 94143 USA; Trinity Coll Dublin, Global Brain Hlth Inst GBHI, Dublin, Ireland
· JAVANDEL, Shireen:Univ Calif San Francisco, Dept Neurol, Memory & Aging Ctr, San Francisco, CA 94143 USA
· KOSIK, Kenneth S.:Univ Calif Santa Barbara, Dept Mol Cellular & Dev Biol, Neurosci Res Inst, Santa Barbara, CA 93106 USA
· VALCOUR, Victor:Univ Calif San Francisco, Global Brain Hlth Inst GBHI, San Francisco, CA 94143 USA; Trinity Coll Dublin, Global Brain Hlth Inst GBHI, Dublin, Ireland; Univ Calif San Francisco, Dept Neurol, Memory & Aging Ctr, San Francisco, CA 94143 USA
· MILLER, Bruce L.:Univ Calif San Francisco, Global Brain Hlth Inst GBHI, San Francisco, CA 94143 USA; Trinity Coll Dublin, Global Brain Hlth Inst GBHI, Dublin, Ireland; Univ Calif San Francisco, Dept Neurol, Memory & Aging Ctr, San Francisco, CA 94143 USA
hcfmusp.origem.id WOS:000632549500001
hcfmusp.origem.id 2-s2.0-85103097770
hcfmusp.publisher.city LAUSANNE
hcfmusp.publisher.country SWITZERLAND
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