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dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.authorSANABRIA, Alvaro
dc.contributor.authorKOWALSKI, Luiz P.
dc.contributor.authorNIXON, Iain J.
dc.contributor.authorSIMO, Ricard
dc.identifier.citationLANGENBECKS ARCHIVES OF SURGERY, v.406, n.3, p.563-569, 2021
dc.description.abstractPurpose In the case of well-differentiated thyroid cancer, the importance of microscopic margin status remains controversial. We discuss the relevance of the effect of microscopic positive surgical margins in the early stages of differentiated thyroid cancer. Methods A comprehensive literature search and review of available evidence in English literature was undertaken. Results A previous meta-analysis did not find an association between microscopic positive surgical margins and local recurrence. Heterogeneity of definitions and differences between microscopic surgical margins and extrathyroid extension are discussed. Impact on clinical decision-making is explored. Conclusion The finding of microscopic positive surgical margins in a patient with a thyroid tumor without intraoperative evidence of macroscopic invasion to adjacent structures, with complete resection made by the surgeon and without pathological report of extrathyroid extension, does not have a worse prognostic effect. We present a classification of surgical margins that may help thyroid oncology teams to tailor further management in patients with thyroid cancer.eng
dc.relation.ispartofLangenbecks Archives of Surgery
dc.subjectThyroid neoplasmeng
dc.subjectMargins of excisioneng
dc.titleMicroscopic positive surgical margins in thyroid carcinoma: a proposal for thyroid oncology teamseng
dc.rights.holderCopyright SPRINGEReng
dc.type.versionpublishedVersioneng, Alvaro:Univ Antioquia, Sch Med, Dept Surg, CEXCA Ctr Excelencia Enfermedades Cabeza & Cuello, Cra 51d 62-29, Medellin, Colombia, Iain J.:Univ Edinburgh, Dept Otolaryngol Head & Neck Surg, NHS Lothian, Edinburgh, Midlothian, Scotland, Ricard:Thyroid Oncol Unit Guys & St Thomas Hosp NHS Fdn, Dept Otorhinolaryngol Head & Neck Surg, London, England
hcfmusp.publisher.cityNEW YORKeng
hcfmusp.publisher.countryUNITED STATESeng
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Appears in Collections:

Artigos e Materiais de Revistas Científicas - FM/MCG
Departamento de Cirurgia - FM/MCG

Artigos e Materiais de Revistas Científicas - LIM/28
LIM/28 - Laboratório de Cirurgia Vascular e da Cabeça e Pescoço

Artigos e Materiais de Revistas Científicas - ODS/03
ODS/03 - Saúde e bem-estar

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