Please use this identifier to cite or link to this item: https://observatorio.fm.usp.br/handle/OPI/40561
Title: A longitudinal multiethnic study of biomarkers in systemic lupus erythematosus: Launching the GLADEL 2.0 Study Group
Authors: GOMEZ-PUERTA, Jose A.PONS-ESTEL, Guillermo J.QUINTANA, RosanaNIETO, RominaMORALES, Rosa M. SerranoHARVEY, Guillermina B.WOJDYLA, DanielSCOLNIK, MarinaSOAJE, Carmen FunesMOREYRA, Paula AlbaNOVATTI, ElisaARIZPE, FernandoBERBOTTO, Guillermo A.LUCERO, Luciana GonzalezPORTA, SabrinaPEREZ, NicolasRODRIGUEZ, Anabella M.APPENZELLER, SimoneMONTADON, Ana Carolina de Oliveira e SilvaMONTICIELO, Odirlei AndreCAVALCANTI, Fernando S.RIBEIRO, Francinne MachadoBORBA, Eduardo F.REIS-NETO, Edgard Torres dosNEIRA, OscarCHAHUAN, Jose MiguelMIMICA, MilenaMARTINEZ, Gustavo ArocaTOBON, Gabriel J.VASQUEZ, GloriaQUINTANA-LOPEZ, GerardoALVAREZ, Mario J. MorenoSAAVEDRA, Miguel AngelCRISTOBAL, Mario PerezFRAGOSO-LOYO, HildaAMEZCUA-GUERRA, Luis M.GONZALEZ-BELLO, Yelitza C.ABUD-MENDOZA, CarlosESQUIVEL-VALERIO, Jorge A.DUARTE, MargaritaCOLMAN, Isabel AcostaMORA-TRUJILLO, ClaudiaREATEGUI-SOKOLOVA, CristinaQUIROZ, Armando A. CalvoMUNOZ-LOUIS, RobertoCAIROLI, ErnestoROSAS, IlianaREBELLA, MartinCARDIEL, Mario H.TORRE, Ignacio Garcia de laCATOGGIO, Luis J.ALARCON, Graciela S.PONS-ESTEL, Bernardo A.
Citation: LUPUS, v.30, n.4, p.630-640, 2021
Abstract: Introduction: After more than 20 years of sustained work, the Latin American Group for the Study of Lupus (GLADEL) has made a significant number of contributions to the field of lupus, not only in the differential role that race/ethnicity plays in its course and outcome but also in several other studies including the beneficial effects of using antimalarials in lupus patients and the development of consensus guidelines for the treatment of lupus in our region. Methods: A new generation of ""Lupus Investigators"" in more than 40 centers throughout Latin America has been constituted in order to continue the legacy of the investigators of the original cohort and to launch a novel study of serum and urinary biomarkers in patients with systemic lupus erythematosus. Results: So far, we have recruited 807 patients and 631 controls from 42 Latin-American centers including 339 patients with SLE without renal involvement, 202 patients with SLE with prevalent but inactive renal disease, 176 patients with prevalent and active renal disease and 90 patients with incident lupus nephritis. Conclusions: The different methodological aspects of the GLADEL 2.0 cohort are discussed in this manuscript, including the challenges and difficulties of conducting such an ambitious project.
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Artigos e Materiais de Revistas Científicas - FM/MCM
Departamento de Clínica Médica - FM/MCM

Artigos e Materiais de Revistas Científicas - LIM/17
LIM/17 - Laboratório de Investigação em Reumatologia

Artigos e Materiais de Revistas Científicas - ODS/03


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