Please use this identifier to cite or link to this item: https://observatorio.fm.usp.br/handle/OPI/40972
Title: Metagenomic next-generation sequencing (mNGS) for diagnostically challenging infectious diseases in patients with acute leukemia
Authors: GARNICA, MarciaPIERROTTI, Ligia CameraOLIVEIRA, Paula Vanessa deMAZZI, MarianaCHEBABO, Alberto
Citation: BRAZILIAN JOURNAL OF INFECTIOUS DISEASES, v.25, n.2, article ID 101548, 4p, 2021
Abstract: This report shows the contribution of next-generation metagenomic sequencing (mNGS) as an alternative to challenging diagnostic infection in immunosuppressed individuals. Herein, we report three acute leukemia patients who developed severe invasive infections due to different etiologies: fungi, viruses, and protozoa. mNGS improved the diagnosis of the infections and provided the opportunity for adequate therapy. The mNGS is a hypothesis-free diagnostic platform, increasing potential in challenging diseases in hematological patients due to the extended diagnostic panel and the expedite access to the result. (C) 2021 Sociedade Brasileira de Infectologia.
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Artigos e Materiais de Revistas Científicas - HC/ICHC
Instituto Central - HC/ICHC

Artigos e Materiais de Revistas Científicas - LIM/47
LIM/47 - Laboratório de Hepatologia por Vírus

Artigos e Materiais de Revistas Científicas - ODS/03
ODS/03 - Saúde e bem-estar


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