Please use this identifier to cite or link to this item: https://observatorio.fm.usp.br/handle/OPI/4118
Full metadata record
DC FieldValueLanguage
dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP-
dc.contributor.authorCASTRO, Luiz H.-
dc.contributor.authorSILVA, Liliane C. A. M.-
dc.contributor.authorADDA, Carla C.-
dc.contributor.authorBANASKIWITZ, Natalie H. C.-
dc.contributor.authorXAVIER, Alana B.-
dc.contributor.authorJORGE, Carmen L.-
dc.contributor.authorVALERIO, Rosa M.-
dc.contributor.authorNITRINI, Ricardo-
dc.date.accessioned2014-01-28T22:24:20Z-
dc.date.available2014-01-28T22:24:20Z-
dc.date.issued2013-
dc.identifier.citationEPILEPSIA, v.54, n.10, p.1735-1742, 2013-
dc.identifier.issn0013-9580-
dc.identifier.urihttps://observatorio.fm.usp.br/handle/OPI/4118-
dc.description.abstractPurposeMaterial-specific memory impairment is used as a lateralizing tool in the evaluation of temporal lobe epilepsy. Lateralizing ability of material-specific memory deficits in temporal lobe epilepsy remains controversial. MethodsWe studied memory impairment profiles of verbal and nonverbal memory deficits with eight memory subtests of four neuropsychological instruments (two verbal and two nonverbal) in 87 right-handed patients with epilepsy associated with unilateral mesial temporal sclerosis (MTS; 44 right - R, 43 left - L) and 42 controls, with an IQ>70, at least 8years of education, and without comorbidities. Key FindingsSelective verbal memory impairment was noted in 11 of 43 or 25.6% of left MTS cases, with 82.2% specificity, whereas selective nonverbal memory impairment was noted in 11 of 42 or 26.2% of right MTS cases, with 92% specificity. Nonlateralizing profiles of memory performance were seen in the remaining 65 of 87 patients. Approximately half (46/87 or 52.9%) of the patients had intact memory function in both modalities, equally distributed between patients with right MTS (23/44) and left MTS (23/43). Global impairment of both memory types was seen in 12 of 87 or 13.8% of patients, equally distributed between the two groups (7/43 left and 5/44 right). SignificanceLateralizing profiles of selective verbal and nonverbal memory deficits are highly specific for left and right MTS, although infrequently encountered in our patients. Nonlateralizing profiles predominated in this population. These findings suggest hemispheric asymmetry memory function, with complex functional interaction of the hippocampi, and possible compensatory mechanisms in the setting of a unilateral lesion.-
dc.description.sponsorshipFAPESP [2005/56464-9]-
dc.language.isoeng-
dc.publisherWILEY-BLACKWELL-
dc.relation.ispartofEpilepsia-
dc.rightsrestrictedAccess-
dc.subjectMemory-
dc.subjectMesial temporal sclerosis-
dc.subjectNeuropsychology-
dc.subjectCognition-
dc.subject.othertemporal-lobe epilepsy-
dc.subject.otherneuropsychological tests-
dc.subject.otherlateralizing value-
dc.subject.otherrecall-
dc.subject.otherfoci-
dc.titleLow prevalence but high specificity of material-specific memory impairment in epilepsy associated with hippocampal sclerosis-
dc.typearticle-
dc.rights.holderCopyright WILEY-BLACKWELL-
dc.identifier.doi10.1111/epi.12343-
dc.identifier.pmid23980806-
dc.subject.wosClinical Neurology-
dc.type.categoryoriginal article-
dc.type.versionpublishedVersion-
hcfmusp.author.externalXAVIER, Alana B.:Univ Sao Paulo, Sch Med, Dept Neurol, Sao Paulo, Brazil-
hcfmusp.description.beginpage1735-
hcfmusp.description.endpage1742-
hcfmusp.description.issue10-
hcfmusp.description.volume54-
hcfmusp.origemWOS-
hcfmusp.origem.idWOS:000325141500006-
hcfmusp.origem.id2-s2.0-84885371241-
hcfmusp.publisher.cityHOBOKEN-
hcfmusp.publisher.countryUSA-
hcfmusp.relation.referenceBaxendale S, 2010, EPILEPSIA, V51, P2225, DOI 10.1111/j.1528-1167.2010.02710.x-
hcfmusp.relation.referenceBaxendale SA, 1998, EPILEPSIA, V39, P158, DOI 10.1111/j.1528-1157.1998.tb01353.x-
hcfmusp.relation.referenceBell B, 2011, NAT REV NEUROL, V7, P154, DOI 10.1038/nrneurol.2011.3-
hcfmusp.relation.referenceBonelli SB, 2010, BRAIN, V133, P1186, DOI 10.1093/brain/awq006-
hcfmusp.relation.referenceBonnici HM, 2013, EPILEPSY RES, V105, P140, DOI 10.1016/j.eplepsyres.2013.01.004-
hcfmusp.relation.referenceDabbs K, 2009, EPILEPSY BEHAV, V15, P445, DOI 10.1016/j.yebeh.2009.05.012-
hcfmusp.relation.referenceDeckers CLP, 1997, EPILEPSIA, V38, P570, DOI 10.1111/j.1528-1157.1997.tb01142.x-
hcfmusp.relation.referenceGolby AJ, 2001, BRAIN, V124, P1841, DOI 10.1093/brain/124.9.1841-
hcfmusp.relation.referenceGrammaldo LG, 2006, EUR J NEUROL, V13, P371, DOI 10.1111/j.1468-1331.2006.01236.x-
hcfmusp.relation.referenceHERMANN BP, 1995, J EPILEPSY, V8, P139, DOI 10.1016/0896-6974(95)00022-6-
hcfmusp.relation.referenceJONESGOTMAN M, 1986, NEUROPSYCHOLOGIA, V24, P659, DOI 10.1016/0028-3932(86)90005-9-
hcfmusp.relation.referenceKeary TA, 2007, EPILEPSIA, V48, P1438, DOI 10.1111/j.1528-1167.2007.01098.x-
hcfmusp.relation.referenceKennepohl S, 2007, NEUROIMAGE, V36, P969, DOI 10.1016/j.neuroimage.2007.03.049-
hcfmusp.relation.referenceKim H, 2004, NEUROPSYCHOLOGY, V18, P141, DOI 10.1037/0894-4105.18.1.141-
hcfmusp.relation.referenceKoylu B, 2008, BRAIN RES, V1223, P73, DOI 10.1016/j.brainres.2008.05.075-
hcfmusp.relation.referenceLoring DW, 1989, PSYCHOL ASSESSMENT J, V1, P198-
hcfmusp.relation.referenceLoring DW, 1988, J EPILEPSY, V1, P53, DOI 10.1016/S0896-6974(88)80057-4-
hcfmusp.relation.referenceLoring DW, 2000, J CLIN PSYCHOL, V56, P563, DOI 10.1002/(SICI)1097-4679(200004)56:4<563::AID-JCLP9>3.0.CO;2-K-
hcfmusp.relation.referenceNaugle RI, 1994, ASSESSMENT, V1, P373-
hcfmusp.relation.referencePIGUET O, 1994, ARCH CLIN NEUROPSYCH, V9, P451, DOI 10.1016/0887-6177(94)90007-8-
hcfmusp.relation.referenceRaspall T, 2005, SEIZURE-EUR J EPILEP, V14, P569, DOI 10.1016/j.seizure.2005.09.007-
hcfmusp.relation.referenceRey A., 1942, ARCH PSYCHOL, V28, P112-
hcfmusp.relation.referenceRey A., 1999, TESTE COPIA REPROD M-
hcfmusp.relation.referenceSawrie SM, 2001, EPILEPSIA, V42, P651, DOI 10.1046/j.1528-1157.2001.30200.x-
hcfmusp.relation.referenceSherman EMS, 2011, EPILEPSIA, V52, P857, DOI 10.1111/j.1528-1167.2011.03022.x-
hcfmusp.relation.referenceSpreen O, 1998, COMPENDIUM NEUROPSYC-
dc.description.indexMEDLINE-
hcfmusp.remissive.sponsorshipFAPESP-
hcfmusp.citation.scopus21-
hcfmusp.scopus.lastupdate2022-04-15-
Appears in Collections:

Artigos e Materiais de Revistas Científicas - FM/MNE
Departamento de Neurologia - FM/MNE

Artigos e Materiais de Revistas Científicas - HC/ICHC
Instituto Central - HC/ICHC

Artigos e Materiais de Revistas Científicas - LIM/15
LIM/15 - Laboratório de Investigação em Neurologia

Artigos e Materiais de Revistas Científicas - LIM/22
LIM/22 - Laboratório de Patolologia Cardiovascular

Artigos e Materiais de Revistas Científicas - LIM/45
LIM/45 - Laboratório de Fisiopatologia Neurocirúrgica


Files in This Item:
File Description SizeFormat 
art_CASTRO_Low_prevalence_but_high_specificity_of_material_specific_2013.PDF
  Restricted Access
publishedVersion (English)89.45 kBAdobe PDFView/Open Request a copy

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.