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https://observatorio.fm.usp.br/handle/OPI/4123
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DC Field | Value | Language |
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dc.contributor | Sistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP | - |
dc.contributor.author | PEZATO, Rogerio | - |
dc.contributor.author | BALSALOBRE, Leonardo | - |
dc.contributor.author | LIMA, Milena | - |
dc.contributor.author | BEZERRA, Thiago F. P. | - |
dc.contributor.author | VOEGELS, Richard L. | - |
dc.contributor.author | GREGORIO, Luis Carlos | - |
dc.contributor.author | STAMM, Aldo Cassol | - |
dc.contributor.author | ZELE, Thibaut van | - |
dc.date.accessioned | 2014-01-28T22:24:58Z | - |
dc.date.available | 2014-01-28T22:24:58Z | - |
dc.date.issued | 2013 | - |
dc.identifier.citation | JOURNAL OF OTOLARYNGOLOGY-HEAD & NECK SURGERY, v.42, article ID 27, 5p, 2013 | - |
dc.identifier.issn | 1916-0216 | - |
dc.identifier.uri | https://observatorio.fm.usp.br/handle/OPI/4123 | - |
dc.description.abstract | This review is addressed two pathophysiologic mechanisms implicated in the pathogenesis of nasal polyposis: the unique remodeling process found in nasal polyp tissue and the immune response of patients with nasal polyposis to Staphylococcus aureus. These two theories converge to the same direction in different aspects, including decreased extracellular matrix production, impaired T regulation and favoring of a Th2 immune response. In patients with nasal polyposis, an exaggerated immune response to Staphylococcus aureus may aggravate the airway remodeling process. | - |
dc.language.iso | eng | - |
dc.publisher | BIOMED CENTRAL LTD | - |
dc.relation.ispartof | Journal of Otolaryngology-Head & Neck Surgery | - |
dc.rights | openAccess | - |
dc.subject | Airway remodeling | - |
dc.subject | Superantigens | - |
dc.subject | Nasal polyps | - |
dc.subject.other | growth-factor-beta | - |
dc.subject.other | chronic rhinosinusitis | - |
dc.subject.other | tgf-beta | - |
dc.subject.other | matrix metalloproteinases | - |
dc.subject.other | tissue inhibitor | - |
dc.subject.other | ige | - |
dc.subject.other | enterotoxins | - |
dc.subject.other | expression | - |
dc.subject.other | cells | - |
dc.subject.other | differentiation | - |
dc.title | Convergence of two major pathophysiologic mechanisms in nasal polyposis: immune response to Staphylococcus aureus and airway remodeling | - |
dc.type | article | - |
dc.rights.holder | Copyright BIOMED CENTRAL LTD | - |
dc.identifier.doi | 10.1186/1916-0216-42-27 | - |
dc.identifier.pmid | 23663431 | - |
dc.subject.wos | Otorhinolaryngology | - |
dc.type.category | review | - |
dc.type.version | publishedVersion | - |
hcfmusp.author.external | PEZATO, Rogerio:Univ Fed Sao Paulo, Dept Otolaryngol Head & Neck Surg, BR-02526060 Sao Paulo, Brazil; Univ Ghent, Dept Otorhinolaryngol, Ghent Univ Hosp, B-9000 Ghent, Belgium | - |
hcfmusp.author.external | BALSALOBRE, Leonardo:Univ Fed Sao Paulo, Dept Otolaryngol Head & Neck Surg, BR-02526060 Sao Paulo, Brazil | - |
hcfmusp.author.external | LIMA, Milena:Mil Police Hosp, Sao Paulo, Brazil | - |
hcfmusp.author.external | GREGORIO, Luis Carlos:Univ Fed Sao Paulo, Dept Otolaryngol Head & Neck Surg, BR-02526060 Sao Paulo, Brazil | - |
hcfmusp.author.external | STAMM, Aldo Cassol:Univ Fed Sao Paulo, Dept Otolaryngol Head & Neck Surg, BR-02526060 Sao Paulo, Brazil | - |
hcfmusp.author.external | ZELE, Thibaut van:Univ Ghent, Dept Otorhinolaryngol, Ghent Univ Hosp, B-9000 Ghent, Belgium | - |
hcfmusp.description.articlenumber | 27 | - |
hcfmusp.description.volume | 42 | - |
hcfmusp.origem | WOS | - |
hcfmusp.origem.id | WOS:000318410000002 | - |
hcfmusp.origem.id | 2-s2.0-84896913550 | - |
hcfmusp.publisher.city | LONDON | - |
hcfmusp.publisher.country | ENGLAND | - |
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dc.description.index | MEDLINE | - |
hcfmusp.citation.scopus | 20 | - |
hcfmusp.scopus.lastupdate | 2024-03-29 | - |
Appears in Collections: | Artigos e Materiais de Revistas Científicas - FM/MOF Artigos e Materiais de Revistas Científicas - HC/ICHC Artigos e Materiais de Revistas Científicas - LIM/32 |
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art_BEZERRA_Convergence_of_two_major_pathophysiologic_mechanisms_in_nasal_2013.PDF | publishedVersion (English) | 258.87 kB | Adobe PDF | View/Open |
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