Please use this identifier to cite or link to this item: https://observatorio.fm.usp.br/handle/OPI/41550
Full metadata record
DC FieldValueLanguage
dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.authorZUCCHI, Eliana Miura
dc.contributor.authorCOUTO, Marcia Thereza
dc.contributor.authorCASTELLANOS, Marcelo
dc.contributor.authorDUMONT-PENA, Erica
dc.contributor.authorFERRAZ, Dulce
dc.contributor.authorPINHEIRO, Thiago Felix
dc.contributor.authorGRANGEIRO, Alexandre
dc.contributor.authorSILVA, Luis Augusto Vasconcelos da
dc.contributor.authorDOURADO, Ines
dc.contributor.authorPEDRANA, Leo
dc.contributor.authorSANTOS, Fernanda Soares de Resende
dc.contributor.authorMAGNO, Laio
dc.date.accessioned2021-08-13T15:15:30Z-
dc.date.available2021-08-13T15:15:30Z-
dc.date.issued2021
dc.identifier.citationPLOS ONE, v.16, n.5, article ID e0249293, 20p, 2021
dc.identifier.issn1932-6203
dc.identifier.urihttps://observatorio.fm.usp.br/handle/OPI/41550-
dc.description.abstractBackground Adolescents face socio-structural, personal and programmatic barriers to HIV prevention services, highlighting the importance of understanding knowledge and acceptability as essential aspects to promote their broader access to pre-exposure prophylaxis (PrEP). We analyzed the acceptability of PrEP among adolescent men who have sex with men (MSM), travestis and transgender women (TGW). Methods A qualitative investigation was conducted as part of the formative research of the PrEP15-19 study, an ongoing demonstration study that analyzes the effectiveness of daily PrEP among adolescent MSM, travestis and TGW aged 15-19 in three Brazilian cities. A total of 37 semi-structured interviews and 6 focus groups were conducted. Building from thematic analysis focusing on participants' sexual encounters, perceptions about PrEP efficacy, and vulnerability contexts, we analyzed prospective acceptability of PrEP. Findings Knowledge about PrEP was incipient and characterized by adolescents' frequent doubts about its prescription and efficacy. The 'ideal' use of PrEP appeared together with consistent condom use, especially in casual sex. PrEP use was also mentioned as depending on increased learning about prevention management over time. Main barriers to PrEP use included the incorporation of a daily medication into participants' routine and its impact on their social lives, especially related to stigma. Concerns over short- and long-term side effects were also reported as barriers to PrEP use. TGW and travestis contrasted using PrEP with the precarity of their life conditions, and some expressed a critical vision about PrEP by associating it with pharmaceuticalization and trans necropolitics. Conclusions Participants' low knowledge and acceptability of PrEP are circumscribed by a rigid perception of condom as the ideal prevention method and the context of their sexual relations. Prospective acceptability highlights that the successful uptake of PrEP depends on overcoming barriers of access to health services and confronting transphobia and homophobia as part of care.eng
dc.description.sponsorshipUnitaid [2017-15-FIOTECPrEP]
dc.description.sponsorshipBrazilian Ministry of Health, through the Department of Chronic Diseases and Sexually Transmitted Infections, Bahia State Department of Health, Sao Paulo State and City Department of Health
dc.description.sponsorshipCity of Sao Paulo AIDS Program
dc.language.isoeng
dc.publisherPUBLIC LIBRARY SCIENCEeng
dc.relation.ispartofPlos One
dc.rightsopenAccesseng
dc.subject.otherhiv preventioneng
dc.subject.otherprepeng
dc.subject.otherfacilitatorseng
dc.subject.otherbarrierseng
dc.subject.otherhealtheng
dc.subject.othercareeng
dc.subject.otherknowledgeeng
dc.subject.otherriskeng
dc.titleAcceptability of daily pre-exposure prophylaxis among adolescent men who have sex with men, travestis and transgender women in Brazil: A qualitative studyeng
dc.typearticleeng
dc.rights.holderCopyright PUBLIC LIBRARY SCIENCEeng
dc.identifier.doi10.1371/journal.pone.0249293
dc.identifier.pmid33945527
dc.subject.wosMultidisciplinary Scienceseng
dc.type.categoryoriginal articleeng
dc.type.versionpublishedVersioneng
hcfmusp.author.externalZUCCHI, Eliana Miura:Univ Catolica Santos, Programa Posgrad Saude Colet, Psicol & Polit Publ, Santos, SP, Brazil
hcfmusp.author.externalCASTELLANOS, Marcelo:Univ Fed Bahia, Inst Saude Colet, Salvador, BA, Brazil
hcfmusp.author.externalDUMONT-PENA, Erica:Univ Fed Minas Gerais, Dept Enfermagem Materno Infantil & Saude Publ, Belo Horizonte, MG, Brazil
hcfmusp.author.externalFERRAZ, Dulce:Fundacao Oswaldo Cruz, Escola FIOCRUZ Governo, Brasilia, DF, Brazil
hcfmusp.author.externalSILVA, Luis Augusto Vasconcelos da:Univ Fed Bahia, Inst Humanidades Artes & Ciencias, Salvador, BA, Brazil
hcfmusp.author.externalDOURADO, Ines:Univ Fed Bahia, Inst Saude Colet, Salvador, BA, Brazil
hcfmusp.author.externalPEDRANA, Leo:Univ Fed Bahia, Inst Saude Colet, Salvador, BA, Brazil
hcfmusp.author.externalSANTOS, Fernanda Soares de Resende:Univ Fed Minas Gerais, Programa Posgrad Enfermagem, Belo Horizonte, MG, Brazil
hcfmusp.author.externalMAGNO, Laio:Univ Fed Bahia, Inst Saude Colet, Salvador, BA, Brazil; Univ Estado Bahia, Dept Ciencias Vida, Salvador, BA, Brazil
hcfmusp.description.articlenumbere0249293
hcfmusp.description.issue5
hcfmusp.description.volume16
hcfmusp.origemWOS
hcfmusp.origem.idWOS:000664609600005
hcfmusp.origem.id2-s2.0-85105303631
hcfmusp.publisher.citySAN FRANCISCOeng
hcfmusp.publisher.countryUSAeng
hcfmusp.relation.referenceAl-Tayyib AA, 2014, AIDS BEHAV, V18, pS340, DOI 10.1007/s10461-013-0553-6eng
hcfmusp.relation.referenceAlhojailan M.I., 2012, W E J SOCIAL SCI, V1, P39eng
hcfmusp.relation.referenceBarreras JL., 2019, AIDS CARE, V31, P1221, DOI [10.1080/09540121.2019.1601669, DOI 10.1080/09540121.2019.1601669]eng
hcfmusp.relation.referenceBento B., 2018, Cad Pagu, V53eng
hcfmusp.relation.referenceBiskupiak A, 2018, LGBT HEALTH, V5, P469, DOI 10.1089/lgbt.2018.0102eng
hcfmusp.relation.referenceBourne A, 2017, J INT AIDS SOC, V20, DOI 10.7448/IAS.20.1.21899eng
hcfmusp.relation.referenceBury M, 2001, SOCIOL HEALTH ILL, V23, P263, DOI 10.1111/1467-9566.00252eng
hcfmusp.relation.referenceCaravaca-Morera JA., 2018, TEXTO CONTEXT ENFERM, V27, P1eng
hcfmusp.relation.referenceChakrapani V, 2020, AIDS PATIENT CARE ST, V34, P92, DOI 10.1089/apc.2019.0237eng
hcfmusp.relation.referenceCohen SE, 2015, JAIDS-J ACQ IMM DEF, V68, P439, DOI 10.1097/QAI.0000000000000479eng
hcfmusp.relation.referenceda Silva LAV, 2021, SOCIOL HEALTH ILL, V43, P424, DOI 10.1111/1467-9566.13230eng
hcfmusp.relation.referencede Camargo KR, 2013, CAD SAUDE PUBLICA, V29, P844eng
hcfmusp.relation.referenceFerraz D, 2019, SEX REPROD HLTH MATT, V27, P107, DOI 10.1080/26410397.2019.1650587eng
hcfmusp.relation.referenceFisher CB, 2017, AIDS EDUC PREV, V29, P205, DOI 10.1521/aeap.2017.29.3.205eng
hcfmusp.relation.referenceGibson BA, 2016, GLOB PUBLIC HEALTH, V11, P1010, DOI 10.1080/17441692.2015.1134614eng
hcfmusp.relation.referenceGolub SA, 2013, AIDS PATIENT CARE ST, V27, P248, DOI 10.1089/apc.2012.0419eng
hcfmusp.relation.referenceHoagland B, 2017, AIDS BEHAV, V21, P1278, DOI 10.1007/s10461-016-1516-5eng
hcfmusp.relation.referenceHugo JM, 2016, AIDS BEHAV, V20, pS357, DOI 10.1007/s10461-016-1536-1eng
hcfmusp.relation.referenceIniesta C, 2018, PLOS ONE, V13, DOI 10.1371/journal.pone.0204738eng
hcfmusp.relation.referenceJohnston LG, 2010, AIDS CARE, V22, P784, DOI 10.1080/09540120903373557eng
hcfmusp.relation.referenceLeinung MC, 2013, ENDOCR PRACT, V19, P644, DOI 10.4158/EP12170.OReng
hcfmusp.relation.referenceMabire X, 2019, AM J MENS HEALTH, V13, DOI 10.1177/1557988319827396eng
hcfmusp.relation.referenceMagno L, 2019, CAD SAUDE PUBLICA, V35, P1eng
hcfmusp.relation.referenceMagno L, 2018, PLOS ONE, V13, DOI 10.1371/journal.pone.0194306eng
hcfmusp.relation.referenceMalta Monica, 2005, Cad. Saúde Pública, V21, P1424, DOI 10.1590/S0102-311X2005000500015eng
hcfmusp.relation.referenceMayer KH, 2013, JAIDS-J ACQ IMM DEF, V63, pS161, DOI 10.1097/QAI.0b013e318298700eeng
hcfmusp.relation.referenceMbembe A, 2003, PUBLIC CULTURE, V15, P11, DOI 10.1215/08992363-15-1-11eng
hcfmusp.relation.referencePeng LP, 2019, INT J ENV RES PUB HE, V16, DOI 10.3390/ijerph16142620eng
hcfmusp.relation.referenceRace K, 2016, GLQ-J LESBIAN GAY ST, V22, P1, DOI 10.1215/10642684-3315217eng
hcfmusp.relation.referenceRael CT, 2019, AIDS BEHAV, V23, P2779, DOI 10.1007/s10461-019-02584-8eng
hcfmusp.relation.referenceRhodes SD, 2015, HEALTH PROMOT INT, V30, P832, DOI 10.1093/heapro/dau013eng
hcfmusp.relation.referenceSeffner F, 2016, INTERFACE-BOTUCATU, V20, P293, DOI 10.1590/1807-57622015.0459eng
hcfmusp.relation.referenceSekhon M, 2017, BMC HEALTH SERV RES, V17, DOI 10.1186/s12913-017-2031-8eng
hcfmusp.relation.referenceSerota DP, 2020, CLIN INFECT DIS, V71, P574, DOI 10.1093/cid/ciz894eng
hcfmusp.relation.referenceSevelius JM, 2014, ANN BEHAV MED, V47, P5, DOI 10.1007/s12160-013-9565-8eng
hcfmusp.relation.referenceSun CJ, 2019, AIDS EDUC PREV, V31, P51, DOI 10.1521/aeap.2019.31.1.51eng
hcfmusp.relation.referenceTagliamento G, 2016, J HOMOSEXUAL, V63, P1556, DOI 10.1080/00918369.2016.1223359eng
hcfmusp.relation.referenceTorres TS., 2019, J MED INTERNET RES, V31, P1193eng
hcfmusp.relation.referenceWinter S, 2016, LANCET, V388, P390, DOI 10.1016/S0140-6736(16)00683-8eng
hcfmusp.relation.referenceWoodford MR, 2016, GLOB PUBLIC HEALTH, V11, P363, DOI 10.1080/17441692.2015.1057757eng
hcfmusp.relation.referenceYi S, 2017, J INT AIDS SOC, V20, DOI 10.7448/IAS.20.1.21580eng
hcfmusp.relation.referenceZucchi EM, 2018, CAD SAUDE PUBLICA, V34, DOI [10.1590/0102-311X00206617, 10.1590/0102-311x00206617]eng
dc.description.indexMEDLINEeng
hcfmusp.citation.scopus0-
hcfmusp.scopus.lastupdate2022-07-21-
Appears in Collections:

Artigos e Materiais de Revistas Científicas - FM/MPR
Departamento de Medicina Preventiva - FM/MPR

Artigos e Materiais de Revistas Científicas - LIM/38
LIM/38 - Laboratório de Epidemiologia e Imunobiologia

Artigos e Materiais de Revistas Científicas - LIM/39
LIM/39 - Laboratório de Processamento de Dados Biomédicos

Artigos e Materiais de Revistas Científicas - ODS/03
ODS/03 - Saúde e bem-estar

Artigos e Materiais de Revistas Científicas - ODS/05
ODS/05 - Igualdade de gênero


Files in This Item:
File Description SizeFormat 
art_ZUCCHI_Acceptability_of_daily_preexposure_prophylaxis_among_adolescent_men_2021.PDFpublishedVersion (English)587.74 kBAdobe PDFThumbnail
View/Open

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.