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https://observatorio.fm.usp.br/handle/OPI/41681
Title: | Role of neutrophil-lymphocyte ratio as a predictive factor of glioma tumor grade: A systematic review |
Authors: | SANTOS, Alexandra Gomes dos; CARVALHO, Rodolfo Figueiredo de; MORAIS, Artur Nobrega Lima Rodrigues de; SILVA, Tamires Martins; BAYLAO, Victor Matheus Ribeiro; AZEVEDO, Mayara; OLIVEIRA, Adilson J. M. de |
Citation: | CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY, v.163, article ID 103372, 7p, 2021 |
Abstract: | Gliomas are the main type of intra-axial primary brain tumors. We performed a systematic review of studies on the neutrophil-to-lymphocyte ratio (NLR) and its role in the prognosis of patients with gliomas. An English-language literature-based search, using the PubMed and Biblioteca Virtual em Saude databases, was conducted for papers published until May 2, 2020. The quality of the selected articles was stratified using the Newcastle-Ottawa scale's criteria. We found 137 publications for a query string. After applying the inclusion criteria, 13 articles were selected. Seven studies assessed overall survival and found high NLR values associated with poor overall survival. Six studies approached the issue of tumor grading and differential diagnosis and demonstrated that patients with high NLR values were diagnosed with high-grade gliomas. NLR is a low-cost method and an effective prognostic factor associated with tumor grading and OS in patients with gliomas. |
Appears in Collections: | Artigos e Materiais de Revistas Científicas - HC/ICHC Artigos e Materiais de Revistas Científicas - LIM/61 Artigos e Materiais de Revistas Científicas - LIM/62 Artigos e Materiais de Revistas Científicas - ODS/03 |
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