Please use this identifier to cite or link to this item:
https://observatorio.fm.usp.br/handle/OPI/43760
Title: | Associacao Brasileira de Hematologia, Hemoterapia e Terapia Celular Consensus on genetically modified cells. II: CAR-T cell therapy for patients with CD19+ acute lymphoblastic leukemia |
Authors: | SEBER, Adriana; CASTRO JUNIOR, Claudio Galvao de; KERBAUY, Lucila N.; V, Alexandre Hirayama; BONFIM, Carmem; FERNANDES, Juliana Folloni; SOUZA, Mair; SCHAFELL, Rony; NABHAN, Samir; LOGGETTO, Sandra Regina; SIMOES, Belinda Pinto; ROCHA, Vanderson; LIMA, Marcos de; GUERINO-CUNHA, Renato L.; BITTENCOURT, Henrique |
Citation: | HEMATOLOGY TRANSFUSION AND CELL THERAPY, v.43, suppl.2, p.S13-S21, 2021 |
Abstract: | Chimeric antigen receptor T (CAR-T) cell therapy is a novel therapeutic modality for acute lymphoblastic leukemia (ALL) with robust outcomes in patients with refractory or relapsed disease. At the same time, CAR-T cell therapy is associated with unique and potentially fatal toxicities, such as cytokine release syndrome (CRS) and neurological toxicities (ICANS). This manuscript aims to provide a consensus of specialists in the fields of Hematology Oncology and Cellular Therapy to make recommendations on the current scenario of the use of CAR-T cells in patients with ALL. (C) 2021 Published by Elsevier Espana, S.L.U. on behalf of Associacao Brasileira de Hematologia, Hemoterapia e Terapia Celular. |
Appears in Collections: | Artigos e Materiais de Revistas Científicas - FM/MCM Artigos e Materiais de Revistas Científicas - HC/ICHC Artigos e Materiais de Revistas Científicas - HC/ICr Artigos e Materiais de Revistas Científicas - LIM/31 Artigos e Materiais de Revistas Científicas - LIM/36 Artigos e Materiais de Revistas Científicas - ODS/03 |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
art_SEBER_Associacao_Brasileira_de_Hematologia_Hemoterapia_e_Terapia_Celular_2021.PDF | publishedVersion (English) | 361.85 kB | Adobe PDF | View/Open |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.