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https://observatorio.fm.usp.br/handle/OPI/44145
Title: | Orthohepadnavirus infection in a neotropical bat (Platyrrhinus lineatus) |
Authors: | SOUZA, Alex Junior Souza de; MALHEIROS, Andreza Pinheiro; CHAGAS, Andre Antonio Correa das; PAIVA, Vera Lisa Generosa da Silva; LAURI, Liura Sanchez; SCHEFFER, Karin Correa; MORI, Enio; GOMES-GOUVEA, Michele Soares; PINHO, Joao Renato Rebello; SA, Lilian Rose Marques de |
Citation: | COMPARATIVE IMMUNOLOGY MICROBIOLOGY AND INFECTIOUS DISEASES, v.79, article ID 101713, 6p, 2021 |
Abstract: | Hepatitis B virus (HBV) is the prototype of the Orthohepadnavirus genus and represents an important cause of chronic hepatitis, liver cirrhosis, and hepatic cancer in humans worldwide. To verify the occurrence and genetic variability of orthohepadnavirus among neotropical bats, we tested 81 liver samples of New World bats from Sa similar to o Paulo State, Southeastern Brazil, collected during 2012. PCR, sequencing, and phylogenetic analysis of Surface/ Polymerase and Core viral genes confirmed the occurrence of the first isolate of bat orthohepadnavirus detected in South America. These results may contribute to subsequent studies of the origin, variability, host species, and evolution of bat orthohepadnaviruses in South America. |
Appears in Collections: | Artigos e Materiais de Revistas Científicas - HC/ICHC Artigos e Materiais de Revistas Científicas - IMT Artigos e Materiais de Revistas Científicas - LIM/03 Artigos e Materiais de Revistas Científicas - LIM/07 Artigos e Materiais de Revistas Científicas - ODS/03 |
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