ODS/10 - Redução da desigualdade
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Expression profile of SARS-CoV-2 cellular entry proteins in normal oral mucosa and oral squamous cell carcinoma
CLINICAL AND EXPERIMENTAL DENTAL RESEARCH, v.8, n.1, p.117-122, 2022
Objective: Besides angiotensin converting enzyme 2 (ACE2), an active involvement of proteases (FURIN and/or TMPRSS2) is important for cellular entry of SARS-CoV-2. Therefore, a simultaneous expression profiling of entry proteins in a tissue might provide a better risk assessment of SARS-CoV-2 inf...
Sex and gender in interstitial lung diseases
EUROPEAN RESPIRATORY REVIEW, v.30, n.162, article ID 210105, 12p, 2021
Sex and gender differences influence key domains of research, lung health, healthcare access and healthcare delivery. In interstitial lung diseases (ILDs), mouse models of pulmonary fibrosis are clearly influenced by sex hormones. Additionally, short telomeres, a biomarker of telomere regulation ...
Brazilian Psychiatric Association guidelines for the management of suicidal behavior. Part 1. Risk factors, protective factors, and assessment
BRAZILIAN JOURNAL OF PSYCHIATRY, v.43, n.5, p.525-537, 2021
Suicide is a global public health problem that causes the loss of more than 800,000 lives each year, principally among young people. In Brazil, the average mortality rate attributable to suicide is approximately 5.23 per 100,000 population. Although many guidelines have been published for the man...
The impact of SARS-CoV-2 in dementia across Latin America: A call for an urgent regional plan and coordinated response
ALZHEIMERS & DEMENTIA-TRANSLATIONAL RESEARCH & CLINICAL INTERVENTIONS, v.6, n.1, article ID e12092, 13p, 2020
The SARS-CoV-2 global pandemic will disproportionately impact countries with weak economies and vulnerable populations including people with dementia. Latin American and Caribbean countries (LACs) are burdened with unstable economic development, fragile health systems, massive economic disparitie...
Outcomes of acute basilar artery occlusion-real-world experience in a middle-income country
ACTA NEUROLOGICA SCANDINAVICA, v.145, n.4, p.456-463, 2022
Objectives Our goal was to describe outcomes in a single-center, real-world series of patients with acute basilar artery occlusion in a middle-income country. In addition, we assessed potential outcome predictors. Material and Methods Data from 28 patients were retrospectively reviewed. The prima...
Iron-based phosphorus chelator: Risk of iron deposition and action on bone metabolism in uremic rats
EXPERIMENTAL BIOLOGY AND MEDICINE, v.247, n.5, p.446-452, 2022
Phosphate chelators are frequently used in patients with chronic kidney disease (CKD). New iron-based chelators remain understudied and offer a promising therapeutic option for the control of bone and mineral disorders of chronic kidney disease (BMD-CKD). We assessed the effect of the phosphorus ...
Social inequalities and extreme vulnerability of children and adolescents affected by the COVID-19 pandemic
JOURNAL OF THE ROYAL SOCIETY OF MEDICINE, v.115, n.1, p.36-37, 2022
Photodynamic therapy for squamous cell carcinoma of the head and neck: narrative review focusing on photosensitizers
LASERS IN MEDICAL SCIENCE, v.37, n.3, p.1441-1470, 2022
This narrative review aimed to evaluate the effectiveness of PDT in early or advanced squamous cell carcinoma of the head and neck (SCCHN). Scopus, MEDLINE/PubMed, and Embase were searched electronically following the PRISMA protocol. Quality assessment was performed according to JBI, NIH, and AM...
Experiences of disabled students in undergraduate medical education
MEDICAL TEACHER, v.44, n.3, p.294-299, 2022
Purpose Since people with disabilities (PwD) are underrepresented in medical education, the authors of this article conducted a qualitative research in the form of an in-depth interview with students with disabilities from a medical school in Brazil, to characterize their experiences in medical e...
The impact of cash transfers on mental health in children and young people in low-income and middle-income countries: a systematic review and meta-analysis
BMJ GLOBAL HEALTH, v.6, n.4, article ID e004661, 16p, 2021
Introduction Although cash transfer programmes are not explicitly designed to improve mental health, by reducing poverty and improving the life chances of children and young people, they may also improve their mental health. This systematic review and meta-analysis assessed the evidence on the ef...