Please use this identifier to cite or link to this item: https://observatorio.fm.usp.br/handle/OPI/44477
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dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP-
dc.contributor.authorNOGUEIRA, Adriano Barreto-
dc.contributor.authorTEIXEIRA, Manoel-
dc.date.accessioned2022-02-24T17:16:56Z-
dc.date.available2022-02-24T17:16:56Z-
dc.date.issued2021-
dc.identifier.citationARCHIVES OF NEUROSCIENCE, v.8, n.3, article ID e108154, 7p, 2021-
dc.identifier.issn2322-3944-
dc.identifier.urihttps://observatorio.fm.usp.br/handle/OPI/44477-
dc.description.abstractAging is the main factor for onset of disease. Nonetheless, chronological age does not necessarily correspond to biological age. The regulation of aging, circadian rhythms, and temperature involves the same brain structure: the hypothalamus. We previously showed that the analysis of the circadian rhythm of temperature may predict neurologic signs with 24 hours of antecedence. Our hypothesis is that the circadian rhythm of temperature changes gradually with aging and correlates with biological age. This study aims to assess whether the circadian rhythm of temperature correlates with the chronological age of healthy individuals aged between 18 and 72 years and changes more intensely in individuals with obesity, which is a disease associated with unhealthy aging. To achieve the study goals, 60 individuals will be enrolled and separated into four groups according to age (< or >= 45 years) and health status (healthy or obese). The participants will wear a wristband with vital sign sensors and an accelerometer for three days to detect movement during wake period and lack of movement during sleep period. The ratio between the mean skin temperature during the sleep and preceding wake period will be the main parameter to be analyzed in the study. The possible result is that this ratio is higher in healthy young individuals, as well as healthy age-matched individuals. This could imply the discovery of a simple and non-invasive method related to the biological age that could guide the prevention and treatment of aging-related diseases.eng
dc.language.isoeng-
dc.publisherKOWSAR CORPeng
dc.relation.ispartofArchives of Neuroscience-
dc.rightsopenAccesseng
dc.subjectAgingeng
dc.subjectInternet of Thingseng
dc.subjectCircadian Rhythmseng
dc.subjectBiological Ageeng
dc.subjectWearableeng
dc.titleHealthy Aging Guided by Circadian Rhythm Monitoring Using a Smartwatch-Like Deviceeng
dc.typearticleeng
dc.rights.holderCopyright KOWSAR CORPeng
dc.identifier.doi10.5812/ans.108154-
dc.subject.wosNeuroscienceseng
dc.type.categoryoriginal articleeng
dc.type.versionpublishedVersioneng
hcfmusp.description.articlenumbere108154-
hcfmusp.description.issue3-
hcfmusp.description.volume8-
hcfmusp.origemWOS-
hcfmusp.origem.idWOS:000735480400009-
hcfmusp.publisher.cityTEHRANeng
hcfmusp.publisher.countryIRANeng
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hcfmusp.relation.referenceNogueira A, 2018, BOSTON CHILDRENS HOSeng
hcfmusp.relation.referenceNogueira AB, 2019, Determination or prediction of biological age, rate of aging, or disease installation or outcome by monitoring of the cyclic variation of temperature or other body parameters. Number of publication, Patent No. [WO/2019/166859, 2019166859]eng
hcfmusp.relation.referenceNogueira AB, 2018, NEUROSURGERY, V83, pE133, DOI 10.1093/neuros/nyy252eng
hcfmusp.relation.referenceNogueira AB, 2017, FRONT NEUROL, V8, DOI 10.3389/fneur.2017.00637eng
hcfmusp.relation.referenceNogueira AB, 2017, J TRANSL MED, V15, DOI 10.1186/s12967-017-1272-yeng
hcfmusp.relation.referenceNogueira AB, 2017, NEUROSURGERY, V81, pE16, DOI 10.1093/neuros/nyx202eng
hcfmusp.relation.referenceNogueira AB, 2014, J TRANSL MED, V12, DOI 10.1186/1479-5876-12-75eng
hcfmusp.relation.referencePyrkov TV, 2018, SCI REP-UK, V8, DOI 10.1038/s41598-018-23534-9eng
dc.description.indexPubMedeng
dc.identifier.eissn2322-5769-
Appears in Collections:

Artigos e Materiais de Revistas Científicas - FM/MNE
Departamento de Neurologia - FM/MNE

Artigos e Materiais de Revistas Científicas - HC/ICHC
Instituto Central - HC/ICHC

Artigos e Materiais de Revistas Científicas - LIM/45
LIM/45 - Laboratório de Fisiopatologia Neurocirúrgica

Artigos e Materiais de Revistas Científicas - LIM/62
LIM/62 - Laboratório de Fisiopatologia Cirúrgica


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