https://observatorio.fm.usp.br/handle/OPI/44577
Title: | Effects of neuroplasticity in people with knee osteoarthritis A systematic review of the literature |
Authors: | IUAMOTO, Leandro Ryuchi; ITO, Fabio Luis Kenji; TOME, Thales Augusto; HSING, Wu Tu; MEYER, Alberto; IMAMURA, Marta; BATTISTELLA, Linamara Rizzo |
Citation: | MEDICINE, v.101, n.3, article ID e28616, 10p, 2022 |
Abstract: | Background: Knee osteoarthritis (OA) is associated with chronic inflammation in somatic structures, which alters sensory afferents and leads to plastic changes in the nervous system. Methods: A systematic literature review was carried out, without language restrictions, period, or status of publication. The database used were Medline, EMBASE, Cochrane Library and clinicaltrials.gov. Extra bibliographic references were extracted through the discussion with specialists, and through scientific researches in conference papers. Results: The electronic search found 938 articles. When excluding duplicates and applying the inclusion/exclusion criteria, 5 studies were considered: 2 using EEG and 3 using TMS. Significant reduction of EEG activity in the cingulate medium cortex, reduction of conditioned pain modulation (CPM) in studies with EEG, as well as the occurrence of an association between pain and motor response threshold/intracortical pain facilitation in studies with TMS were observed. Conclusions: The study contributes to a better understanding of the neurophysiological changes seen in the cingulate medium cortex, decrease in CPM and motor response threshold/intracortical pain facilitation. Advances in neuroplasticity studies may aid in the screening for early diagnosis of knee OA in the future. However, more studies are necessary. |
Appears in Collections: | Artigos e Materiais de Revistas Científicas - FM/MLS Artigos e Materiais de Revistas Científicas - FM/MPT Artigos e Materiais de Revistas Científicas - HC/ICHC Artigos e Materiais de Revistas Científicas - HC/IMREA Artigos e Materiais de Revistas Científicas - HC/IOT Artigos e Materiais de Revistas Científicas - LIM/01 Artigos e Materiais de Revistas Científicas - LIM/37 Artigos e Materiais de Revistas Científicas - LIM/41 |
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art_IUAMOTO_Effects_of_neuroplasticity_in_people_with_knee_osteoarthritis_2022.PDF | publishedVersion (English) | 316.69 kB | Adobe PDF | View/Open |
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