Please use this identifier to cite or link to this item:
Full metadata record
DC FieldValueLanguage
dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP-
dc.contributor.authorNALI, Luiz H.-
dc.contributor.authorOLIVAL, Guilherme S.-
dc.contributor.authorMONTENEGRO, Horacio-
dc.contributor.authorSILVA, Israel T. da-
dc.contributor.authorDIAS-NETO, Emmanuel-
dc.contributor.authorNAYA, Hugo-
dc.contributor.authorSPANGENBERG, Lucia-
dc.contributor.authorPENALVA-DE-OLIVEIRA, Augusto C.-
dc.contributor.authorROMANO, Camila M.-
dc.identifier.citationMULTIPLE SCLEROSIS AND RELATED DISORDERS, v.57, article ID 103383, 7p, 2022-
dc.description.abstractMultiple Sclerosis is an autoimmune disease with an unknown etiology. Both genetic and environmental factors are believed to trigger MS autoimmunity. Among the environmental factors, infectious agents have been extensively investigated, and the Human Endogenous Retroviruses (HERVs), especially HERV-W, are believed to be associated with MS pathogenesis. HERVs are derived from ancestral infections and comprise around 8% of the human genome. Although most HERVs are silenced, retroviral genes may be expressed with virion formation. There is extensive evidence of the relationship between HERV-W and MS, including higher levels of HERV-W expression in MS patients, HERV-W protein detection in MS plaques, and the HERV-W env protein inducing an inflammatory response in in vitro and in vivo models. Here we discuss possible links of HERVs and the pathogenesis of MS and present new data regarding the diversity of HERVs expression in samples derived from MS patients.eng
dc.description.sponsorshipFundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP)Fundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP) [2013/24,223-9, 2015/05,958-3]-
dc.publisherELSEVIER SCI LTDeng
dc.relation.ispartofMultiple Sclerosis and Related Disorders-
dc.subject.othert-cell responseseng
dc.subject.otherenvelope proteineng
dc.subject.otherw familyeng
dc.titleHuman endogenous retrovirus and multiple sclerosis: A review and transcriptome findingseng
dc.rights.holderCopyright ELSEVIER SCI LTDeng
dc.subject.wosClinical Neurologyeng
dc.type.versionpublishedVersioneng, Luiz H.:Univ Sao Paulo, Inst Med Trop Silo Paulo, Lab Virol, LIM 52 LIMHC, Rua Dr Eneas de Carvalho Aguiar 470, BR-05403000 Sao Paulo, Brazil; Univ Santo Amaro, Postgrad Program Hlth Sci, Rua Prof Eneas de Siqueira Neto 340, BR-04829300 Sao Paulo, Brazil-, Guilherme S.:Santa Casa Misericordia Sao Paulo, Dept Neurol, R Dr Cesario Mota Jr 112, BR-01221020 Sao Paulo, Brazil-, Horacio:Univ Sao Paulo, ESALQ, Dept Zootecnia, BR-13400183 Piracicaba, SP, Brazil-, Israel T. da:AC Camargo Canc Ctr, Lab Med Genom, BR-01525001 Sao Paulo, Brazil-, Hugo:Inst Pasteur Montevideo, Unidad Bioinformat, Mataojo 2020, Montevideo 11400, Uruguay; Univ Republica, Fac Agron, Dept Prod Anim & Pasturas, Av Gral Eugenio Garzon 780, Montevideo 12900, Uruguay-, Lucia:Inst Pasteur Montevideo, Unidad Bioinformat, Mataojo 2020, Montevideo 11400, Uruguay-, Augusto C.:Santa Casa Misericordia Sao Paulo, Dept Neurol, R Dr Cesario Mota Jr 112, BR-01221020 Sao Paulo, Brazil; Inst Infectol Emilio Ribas, Dept Neurol, Ave Doutor Arnaldo 165, BR-01246900 Sao Paulo, Brazil-
hcfmusp.relation.referenceAntony JM, 2004, NAT NEUROSCI, V7, P1088, DOI 10.1038/nn1319eng
hcfmusp.relation.referenceAntony JM, 2007, AIDS RES HUM RETROV, V23, P1251, DOI 10.1089/aid.2006.0274eng
hcfmusp.relation.referenceArru G., 2015, J NEUROL SCIeng
hcfmusp.relation.referenceArru G, 2014, MULT SCLER J, V20, P174, DOI 10.1177/1352458513494957eng
hcfmusp.relation.referenceBaranzini SE, 2010, NATURE, V464, P1351, DOI 10.1038/nature08990eng
hcfmusp.relation.referenceBelshaw R, 2004, P NATL ACAD SCI USA, V101, P4894, DOI 10.1073/pnas.0307800101eng
hcfmusp.relation.referenceBen Fredj N, 2012, J NEUROVIROL, V18, P12, DOI 10.1007/s13365-011-0056-zeng
hcfmusp.relation.referenceBethariya P., 2017, J EMERG DIS VIROL, V3eng
hcfmusp.relation.referenceBlaise S, 2005, RETROVIROLOGY, V2, DOI 10.1186/1742-4690-2-19eng
hcfmusp.relation.referenceBlond JL, 2000, J VIROL, V74, P3321, DOI 10.1128/JVI.74.7.3321-3329.2000eng
hcfmusp.relation.referenceBrown C, 2016, NATURE, V540, pS4, DOI 10.1038/540S4aeng
hcfmusp.relation.referenceBrowne P, 2014, NEUROLOGY, V83, P1022, DOI 10.1212/WNL.0000000000000768eng
hcfmusp.relation.referenceCallegaro D, 2001, ACTA NEUROL SCAND, V104, P208, DOI 10.1034/j.1600-0404.2001.00372.xeng
hcfmusp.relation.referenceCalmon AB, 2016, NEUROEPIDEMIOLOGY, V46, P88, DOI 10.1159/000442471eng
hcfmusp.relation.referenceCharvet B, 2021, VIROL SIN, V36, P1006, DOI 10.1007/s12250-021-00372-0eng
hcfmusp.relation.referenceCherkasova E, 2016, CANCER RES, V76, P2177, DOI 10.1158/0008-5472.CAN-15-3139eng
hcfmusp.relation.referenceCompston A, 2008, LANCET, V372, P1502, DOI 10.1016/S0140-6736(08)61620-7eng
hcfmusp.relation.referenceContreras-Galindo R, 2006, AIDS RES HUM RETROV, V22, P979, DOI 10.1089/aid.2006.22.979eng
hcfmusp.relation.referenceCurtin F, 2015, MABS-AUSTIN, V7, P265, DOI 10.4161/19420862.2014.985021eng
hcfmusp.relation.referenceDerfuss T, 2015, J NEUROIMMUNOL, V285, P68, DOI 10.1016/j.jneuroim.2015.05.019eng
hcfmusp.relation.referenceDerfuss T, 2015, MULT SCLER J, V21, P885, DOI 10.1177/1352458514554052eng
hcfmusp.relation.referenceDias-Carneiro RPC, 2016, J NEUROIMMUNOL, V300, P30, DOI 10.1016/j.jneuroim.2016.10.001eng
hcfmusp.relation.referencedo Olival GS, 2013, FRONT MICROBIOL, V4, DOI 10.3389/fmicb.2013.00172eng
hcfmusp.relation.referenceDobin A, 2013, BIOINFORMATICS, V29, P15, DOI 10.1093/bioinformatics/bts635eng
hcfmusp.relation.referenceFinkelsztejn A, 2014, ARQ NEURO-PSIQUIAT, V72, P104, DOI 10.1590/0004-282X20130216eng
hcfmusp.relation.referenceFragoso Yara Dadalti, 2007, Rev. bras. epidemiol., V10, P479, DOI 10.1590/S1415-790X2007000400005eng
hcfmusp.relation.referenceGarcia-Montojo M, 2020, EUR J IMMUNOL, V50, P685, DOI 10.1002/eji.201948423eng
hcfmusp.relation.referenceGarcia-Montojo M, 2013, PLOS ONE, V8, DOI 10.1371/journal.pone.0053623eng
hcfmusp.relation.referenceGarrison KE, 2007, PLOS PATHOG, V3, P1617, DOI 10.1371/journal.ppat.0030165eng
hcfmusp.relation.referenceGoff S.Fields, 2005, VIROLOGY, V1st, P165eng
hcfmusp.relation.referenceGriffiths DJ, 2001, GENOME BIOL, V2eng
hcfmusp.relation.referenceHartung HP, 2022, MULT SCLER J, V28, P429, DOI 10.1177/13524585211024997eng
hcfmusp.relation.referenceHuss A, 2016, EXPERT REV MOL DIAGN, V16, P1353, DOI 10.1080/14737159.2016.1249468eng
hcfmusp.relation.referenceJin Y, 2015, BIOINFORMATICS, V31, P3593, DOI 10.1093/bioinformatics/btv422eng
hcfmusp.relation.referenceJones RB, 2012, J CLIN INVEST, V122, P4473, DOI 10.1172/JCI64560eng
hcfmusp.relation.referenceKomurian-Pradel F, 1999, VIROLOGY, V260, P1, DOI 10.1006/viro.1999.9792eng
hcfmusp.relation.referenceKremer D, 2019, P NATL ACAD SCI USA, V116, P15216, DOI 10.1073/pnas.1901283116eng
hcfmusp.relation.referenceKriesel J.D., 2017, J EMERG DIS VIROL, V3eng
hcfmusp.relation.referenceKurtzke JF, 2001, J CLIN EPIDEMIOL, V54, P1, DOI 10.1016/S0895-4356(00)00268-7eng
hcfmusp.relation.referenceLana-Peixoto MA, 2012, ARQ NEURO-PSIQUIAT, V70, P102, DOI 10.1590/S0004-282X2012000200006eng
hcfmusp.relation.referenceLaufer G, 2009, RETROVIROLOGY, V6, DOI 10.1186/1742-4690-6-37eng
hcfmusp.relation.referencede Negreiros AALV, 2015, ARQ NEURO-PSIQUIAT, V73, P741, DOI 10.1590/0004-282X20150111eng
hcfmusp.relation.referenceLi F, 2011, BMC GENOMICS, V12, DOI 10.1186/1471-2164-12-22eng
hcfmusp.relation.referenceMAGER DL, 1989, AM J HUM GENET, V45, P848eng
hcfmusp.relation.referenceMaguire EA, 1998, SCIENCE, V280, P921, DOI 10.1126/science.280.5365.921eng
hcfmusp.relation.referenceMameli G, 2007, J GEN VIROL, V88, P264, DOI 10.1099/vir.0.81890-0eng
hcfmusp.relation.referenceMameli G, 2013, PLOS ONE, V8, DOI 10.1371/journal.pone.0078474eng
hcfmusp.relation.referenceMameli G, 2012, PLOS ONE, V7, DOI 10.1371/journal.pone.0044991eng
hcfmusp.relation.referenceMameli G, 2009, J VIROL METHODS, V161, P98, DOI 10.1016/j.jviromet.2009.05.024eng
hcfmusp.relation.referenceMcCall CE, 2010, J INNATE IMMUN, V2, P395, DOI 10.1159/000314077eng
hcfmusp.relation.referenceMedstrand P, 2001, J BIOL CHEM, V276, P1896, DOI 10.1074/jbc.M006557200eng
hcfmusp.relation.referenceMi S, 2000, NATURE, V403, P785, DOI 10.1038/35001608eng
hcfmusp.relation.referenceMorandi E, 2017, PLOS ONE, V12, DOI 10.1371/journal.pone.0172415eng
hcfmusp.relation.referenceMoreira MA, 2002, REV NEUROLOGIA, V34, P378, DOI 10.33588/rn.3404.2001313eng
hcfmusp.relation.referenceMorris G, 2019, MOL NEUROBIOL, V56, P2590, DOI 10.1007/s12035-018-1255-xeng
hcfmusp.relation.referenceNellaker C, 2006, RETROVIROLOGY, V3, DOI 10.1186/1742-4690-3-44eng
hcfmusp.relation.referenceNora-Krukle Z, 2011, MED LITH, V47, P527eng
hcfmusp.relation.referenceOhl K, 2016, EXP NEUROL, V277, P58, DOI 10.1016/j.expneurol.2015.11.010eng
hcfmusp.relation.referencePakpoor J, 2013, EXPERT REV NEUROTHER, V13, P287, DOI [10.1586/ERN.13.6, 10.1586/ern.13.6]eng
hcfmusp.relation.referencePatience C, 1997, TRENDS GENET, V13, P116, DOI 10.1016/S0168-9525(97)01057-3eng
hcfmusp.relation.referencePerron H, 1997, P NATL ACAD SCI USA, V94, P7583, DOI 10.1073/pnas.94.14.7583eng
hcfmusp.relation.referencePerron H, 2005, J NEUROVIROL, V11, P23, DOI 10.1080/13550280590901741eng
hcfmusp.relation.referencePerron H, 2001, VIROLOGY, V287, P321, DOI 10.1006/viro.2001.1045eng
hcfmusp.relation.referencePerron H, 2000, J NEUROVIROL, V6, pS67eng
hcfmusp.relation.referencePERRON H, 1989, RES VIROLOGY, V140, P551, DOI 10.1016/S0923-2516(89)80141-4eng
hcfmusp.relation.referencePERRON H, 1991, LANCET, V337, P862, DOI 10.1016/0140-6736(91)92579-Qeng
hcfmusp.relation.referencePerron H, 2013, PLOS ONE, V8, DOI 10.1371/journal.pone.0080128eng
hcfmusp.relation.referencePerron H, 2012, MULT SCLER J, V18, P1721, DOI 10.1177/1352458512441381eng
hcfmusp.relation.referencePfuhl C, 2015, J NEUROIMMUNOL, V285, P156, DOI 10.1016/j.jneuroim.2015.06.012eng
hcfmusp.relation.referencePorchet N, 2019, CLIN THER, V41, P1737, DOI 10.1016/j.clinthera.2019.05.020eng
hcfmusp.relation.referenceRamasamy R, 2017, IMMUNOL LETT, V183, P79, DOI 10.1016/j.imlet.2017.02.003eng
hcfmusp.relation.referenceRasmussen H B, 1995, Mult Scler, V1, P82eng
hcfmusp.relation.referenceRedelsperger F, 2016, PLOS GENET, V12, DOI 10.1371/journal.pgen.1006289eng
hcfmusp.relation.referenceRodrigues LS, 2019, AUTOIMMUN HIGHLIGHTS, V10, DOI 10.1186/s13317-019-0122-8eng
hcfmusp.relation.referenceRolland A, 2006, J IMMUNOL, V176, P7636, DOI 10.4049/jimmunol.176.12.7636eng
hcfmusp.relation.referenceRuprecht K, 2008, J VIROL, V82, P10008, DOI 10.1128/JVI.01016-08eng
hcfmusp.relation.referenceSchmitt K, 2013, J VIROL, V87, P13837, DOI 10.1128/JVI.02388-13eng
hcfmusp.relation.referenceSenGupta D, 2011, J VIROL, V85, P6977, DOI 10.1128/JVI.00179-11eng
hcfmusp.relation.referenceSotgiu S, 2002, NEUROLOGY, V59, P1071, DOI 10.1212/WNL.59.7.1071eng
hcfmusp.relation.referenceStuve O, 2009, NEUROLOGY, V72, P396, DOI 10.1212/01.wnl.0000327341.89587.76eng
hcfmusp.relation.referenceTakahashi Y, 2008, J CLIN INVEST, V118, P1099, DOI 10.1172/JCI34409eng
hcfmusp.relation.referenceTING CN, 1992, GENE DEV, V6, P1457, DOI 10.1101/gad.6.8.1457eng
hcfmusp.relation.referenceTorabi M, 2014, NEUROEPIDEMIOLOGY, V43, P38, DOI 10.1159/000365761eng
hcfmusp.relation.referenceVenter JC, 2001, SCIENCE, V291, P1304, DOI 10.1126/science.1058040eng
hcfmusp.relation.referenceVirtanen JO, 2012, CNS NEUROL DISORD-DR, V11, P528eng
hcfmusp.relation.referenceWeiss RA, 2006, RETROVIROLOGY, V3, DOI 10.1186/1742-4690-3-67eng
hcfmusp.relation.referenceWillis SN, 2009, BRAIN, V132, P3318, DOI 10.1093/brain/awp200eng
hcfmusp.relation.referenceZimmermann M, 2015, NEUROL-NEUROIMMUNOL, V2, DOI 10.1212/NXI.0000000000000144eng
Appears in Collections:

Artigos e Materiais de Revistas Científicas - FM/Outros
Outros departamentos - FM/Outros

Artigos e Materiais de Revistas Científicas - LIM/27
LIM/27 - Laboratório de Neurociências

Artigos e Materiais de Revistas Científicas - LIM/52
LIM/52 - Laboratório de Virologia

Files in This Item:
File Description SizeFormat 
  Restricted Access
publishedVersion (English)846.07 kBAdobe PDFView/Open Request a copy

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.