Please use this identifier to cite or link to this item:
Title: Clinical and Eco-Epidemiological Aspects of a Novel Hyperendemic Area of Paracoccidioidomycosis in the Tocantins-Araguaia Basin (Northern Brazil), Caused by Paracoccidioides sp.
Authors: KRAKHECKE-TEIXEIRA, Alessandra G.YAMAUCHI, Danielle H.ROSSI, AlexsandraSOUSA, Herdson R. deGARCES, Hans G.Joaquim L JuniorAntonio O S JuniorFELIPE, Maria Sueli S.BAGAGLI, EduardoANDRADE JR., Heitor F. deTEIXEIRA, Marcus de M.
Citation: JOURNAL OF FUNGI, v.8, n.5, article ID 502, 11p, 2022
Abstract: Paracoccidioidomycosis (PCM) is the most prevalent systemic mycosis in Brazil. The disease is caused by dimorphic fungi nested within the Paracoccidioides genus. We described 106 PCM cases (47.1 cases/year) at the Tropical Diseases Public Hospital of Tocantins State. PCM was prevalent in males and rural workers over 50 years; the chronic pulmonary form predominated in 67% of cases. The male-to-female ratio was 2.65:1, with more women affected than other endemic regions of Brazil. Urban or indoor activities were reported in women and are ascribed to disease urbanization. qPCR-based assays confirmed the identification of Paracoccidioides DNA in 37 biological specimens. Paracoccidioides sp. DNA was found in 53% of the environmental samples, suggesting autochthonous infections. Therefore, the Tocantins-Araguaia basin must be considered a novel hyperendemic area of PCM in Brazil, reinforcing the importance of including PCM as a notifiable disease, requiring specific diagnosis and health measures.
Appears in Collections:

Artigos e Materiais de Revistas Científicas - FM/MPT
Departamento de Patologia - FM/MPT

Artigos e Materiais de Revistas Científicas - LIM/49
LIM/49 - Laboratório de Protozoologia

Files in This Item:
File Description SizeFormat 
art_KRAKHECKE-TEIXEIRA_Clinical_and_EcoEpidemiological_Aspects_of_a_Novel_Hyperendemic_2022.PDFpublishedVersion (English)1.45 MBAdobe PDFThumbnail

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.