Please use this identifier to cite or link to this item: https://observatorio.fm.usp.br/handle/OPI/47428
Title: Ultrahigh resolution spectral-domain optical coherence tomography using the 1000-1600 nm spectral band
Authors: BERNSTEIN, L. I. A. N. E.RAMIER, A. N. T. O. I. N. E.WU, J. I. A. M. I. N.AIELLO, V. E. R. A. D.BELAND, M. A. R. I. E. J.LIN, C. H. A. R. L. E. S. P.YUN, SEOK-HYUN
Citation: BIOMEDICAL OPTICS EXPRESS, v.13, n.4, p.1939-1947, 2022
Abstract: Ultrahigh resolution optical coherence tomography (UHR-OCT) can image micro-scopic features that are not visible with the standard OCT resolution of 5-15 mu m. In previous studies, high-speed UHR-OCT has been accomplished within the visible (VIS) and near-infrared (NIR-I) spectral ranges, specifically within 550-950 nm. Here, we present a spectral domain UHR-OCT system operating in a short-wavelength infrared (SWIR) range from 1000 to 1600 nm using a supercontinuum light source and an InGaAs-based spectrometer. We obtained an axial resolution of 2.6 mu m in air, the highest ever recorded in the SWIR window to our knowledge, with deeper penetration into tissues than VIS or NIR-I light. We demonstrate imaging of conduction fibers of the left bundle branch in freshly excised porcine hearts. These results suggest a potential for deep-penetration, ultrahigh resolution OCT in intraoperative applications. (c) 2022 Optica Publishing Group under the terms of the Optica Open Access Publishing Agreement
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