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dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP-
dc.contributor.authorOLIVAL, Guilherme Sciascia do-
dc.contributor.authorLIMA, Bruna Mendonca-
dc.contributor.authorSUMITA, Laura M.-
dc.contributor.authorSERAFIM, Vitor-
dc.contributor.authorFINK, Maria Cristina-
dc.contributor.authorNALI, Luis Henrique-
dc.contributor.authorROMANO, Camila Malta-
dc.contributor.authorTHOMAZ, Rodrigo Barbosa-
dc.contributor.authorCAVENAGHI, Vitor Breseghello-
dc.contributor.authorTILBERY, Charles Peter-
dc.contributor.authorPENALVA-DE-OLIVEIRA, Augusto Cesar-
dc.date.accessioned2014-04-25T22:14:54Z-
dc.date.available2014-04-25T22:14:54Z-
dc.date.issued2013-
dc.identifier.citationARQUIVOS DE NEURO-PSIQUIATRIA, v.71, n.9B, p.727-730, 2013-
dc.identifier.issn0004-282X-
dc.identifier.urihttps://observatorio.fm.usp.br/handle/OPI/5308-
dc.description.abstractMultiple sclerosis is the most common autoimmune inflammatory demyelinating disease of the central nervous system, and its etiology is believed to have both genetic and environmental components. Several viruses have already been implicated as triggers and there are several studies that implicate members of the Herpesviridae family in the pathogenesis of MS. The most important characteristic of these viruses is that they have periods of latency and exacerbations within their biological sanctuary, the central nervous system. The Epstein-Barr, cytomegalovirus, human herpesvirus 6 and human herpesvirus 7 viruses are the members that are most studied as being possible triggers of multiple sclerosis. According to evidence in the literature, the herpesvirus family is strongly involved in the pathogenesis of this disease, but it is unlikely that they are the only component responsible for its development. There are probably multiple triggers and more studies are necessary to investigate and define these interactions.-
dc.language.isoeng-
dc.publisherASSOC ARQUIVOS NEURO- PSIQUIATRIA-
dc.relation.ispartofArquivos de Neuro-Psiquiatria-
dc.rightsopenAccess-
dc.subjectdemyelinating disease-
dc.subjectbmultiple sclerosis-
dc.subjectherpesvirus-
dc.subject.otherepstein-barr-virus-
dc.subject.otherretrovirus-
dc.subject.otherinfection-
dc.subject.otherrisk-
dc.subject.otherhuman-herpesvirus-6-
dc.subject.otherantibodies-
dc.subject.otherdisease-
dc.subject.othertrigger-
dc.titleMultiple sclerosis and herpesvirus interaction-
dc.typearticle-
dc.rights.holderCopyright ASSOC ARQUIVOS NEURO- PSIQUIATRIA-
dc.identifier.doi10.1590/0004-282X20130160-
dc.identifier.pmid24141514-
dc.subject.wosNeurosciences-
dc.subject.wosPsychiatry-
dc.type.categoryreview-
dc.type.versionpublishedVersion-
hcfmusp.author.externalOLIVAL, Guilherme Sciascia do:Irmandade Santa Casa Misericordia Sao Paulo, Sao Paulo, Brazil-
hcfmusp.author.externalLIMA, Bruna Mendonca:Irmandade Santa Casa Misericordia Sao Paulo, Sao Paulo, Brazil-
hcfmusp.author.externalSERAFIM, Vitor:Santa Casa Sao Paulo, Fac Med Sci, Sao Paulo, Brazil-
hcfmusp.author.externalTHOMAZ, Rodrigo Barbosa:Irmandade Santa Casa Misericordia Sao Paulo, Sao Paulo, Brazil-
hcfmusp.author.externalCAVENAGHI, Vitor Breseghello:Santa Casa Sao Paulo, Fac Med Sci, Sao Paulo, Brazil-
hcfmusp.author.externalTILBERY, Charles Peter:Santa Casa Sao Paulo, Fac Med Sci, Sao Paulo, Brazil-
hcfmusp.author.externalPENALVA-DE-OLIVEIRA, Augusto Cesar:Santa Casa Sao Paulo, Fac Med Sci, Sao Paulo, Brazil-
hcfmusp.description.beginpage727-
hcfmusp.description.endpage730-
hcfmusp.description.issue9B-
hcfmusp.description.volume71-
hcfmusp.origemWOS-
hcfmusp.origem.idWOS:000325306100019-
hcfmusp.origem.id2-s2.0-84885764934-
hcfmusp.origem.idSCIELO:S0004-282X2013001000727-
hcfmusp.publisher.citySAO PAULO SP-
hcfmusp.publisher.countryBRAZIL-
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dc.description.indexMEDLINE-
hcfmusp.citation.scopus16-
hcfmusp.scopus.lastupdate2022-06-24-
Appears in Collections:

Artigos e Materiais de Revistas Científicas - IMT
Instituto de Medicina Tropical - IMT

Artigos e Materiais de Revistas Científicas - LIM/52
LIM/52 - Laboratório de Virologia


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