Please use this identifier to cite or link to this item: https://observatorio.fm.usp.br/handle/OPI/53152
Title: Global Impact of the COVID-19 Pandemic on Stroke Volumes and Cerebrovascular Events A 1-Year Follow-up
Authors: NGUYEN, Thanh N.QURESHI, Muhammad M.KLEIN, PiersYAMAGAMI, HiroshiMIKULIK, RobertCZLONKOWSKA, AnnaABDALKADER, MohamadSEDOVA, PetraSATHYA, AnvithaLO, Hannah C.MANSOUR, Ossama YassinYAMAMOTO, RyooYAZAWA, YukakoSUGIURA, YuriWAWERU, Peter KuriaBAEK, Jang-HyunLEE, Si BaekSEO, Kwon-DukSOHN, Sung-IlARSOVSKA, Anita AnteCHARIDIMOU, AndreasWIENECKE, TroelsCHAN, Yong ChiehZAIDI, Wan Asyraf WanJAAFAR, Ainul SyahrilfazliGONGORA-RIVERA, FernandoMARTINEZ-MARINO, ManuelINFANTE-VALENZUELA, AdrianGROPPA, StanislavLEAHU, PavelCOUTINHO, Jonathan M.RINKEL, Leon A.SOBH, KhalidSIEGLER, James E.DIPPEL, Diederik W. J.DAM-NOLEN, Dianne H. K. VanRANTA, AnnemareiWU, Teddy Y.ADEBAYO, Tajudeen TemitayoBELLO, Abiodun H.NWAZOR, Ernest OkwunduSUNMONU, Taofiki AjaoWAHAB, Kolawole WasiuYLIKOTILA, PauliRONNING, Ole MortenYAGHI, ShadiSANDSET, Else CharlotteHASHMI, Amal M. AlAHMAD, SaimaRASHID, UmairRODRIGUEZ-KADOTA, LilianaYALUNG, Patrick MaticDY, Jon Stewart HaoPINEDA-FRANKS, Maria CarissaALPAY, KemalCO, Christian OliverBROLA, WaldemarSOUSA, Diana Aguiar deDEBIEC, AleksanderDOROBEK, MalgorzataKARLINSKI, Michal AdamLABUZ-ROSZAK, Beata M.LASEK-BAL, AnettaSIENKIEWICZ-JAROSZ, HalinaSTASZEWSKI, JacekSTRBIAN, DanielSOBOLEWSKI, PiotrWIACEK, MarcinZIELINSKA-TUREK, JustynaMOHAMMADEN, Mahmoud H.ARAUJO, Andre PinhoROCHA, MarianaCASTRO, PedroCRUZ, Vitor TedimFERREIRA, Paulo VenancioFERREIRA, PatriciaBERNADY, PatriciaNUNES, Ana PaivaFONSECA, LuisaMARTO, Joao PedroMELO, Teresa Pinho eHAUSSEN, Diogo C.RODRIGUES, MiguelSILVA, M. LuisDIMITRIADE, AdelaFALUP-PECURARIU, CristianHAMID, May AdelCASENAVE, PhilippeVENKETASUBRAMANIAN, NarayanaswamyKRASTEV, GeorgiMAKO, MiroslavAYO-MARTIN, OscarHERNANDEZ-FERANDEZ, FranciscoKRISTOFFERSEN, Espen SaxhaugBLASCO, JordiRODRIGUEZ-VAZQUEZ, AlejandroCRUZ-CULEBRAS, AntonioMONICHE, FranciscoDAN, MariaMONTANER, JoanPEREZ-SANCHEZ, SoledadSANCHEZ, Maria Jesas GarciaRODRIGUEZ, Marta GuillanJOOD, KatarinaNORDANSTIG, AnnikaLEREIS, Virginia PujolV, Michael MazyaMOREIRA, Tiago T. P.BERNAVA, GianmarcoFAUCHEUX, Jean-MarcBEYELER, MorinBOLOGNESE, ManuelCARRERA, EmmanuelDOBROCKY, TomasKARWACKI, Grzegorz MarekKELLER, EmanuelaHSIEH, Chang YangSCOLLO, Sergio DanielBOONYAKARNKUL, SurawanCHUROJANA, AnchaleeGENTRIC, Jean-ChristopheAYKAC, OzlemOZDEMIR, Atilla AzcanBAJRAMI, ArsidaSENADIM, SongulHUSSAIN, Syed IrtezaJOHN, SebyBANERJEE, SomaKWAN, JosephV, Bruce C. CampbellKRISHNAN, KailashVANGURU, Husitha ReddyLENTHALL, RobertMATTHEWS, AshokWONG, KenZHANG, LiqunALTSCHUL, DorotheaASIF, Kaiz S.BAHIRU, ZeelalemBELOW, KristineRULAND, SeanMA, AliceMAGRO, ElsaCHAUDRY, Saqib A.CHEN, MichaelCHEBL, AlexCIBULKA, JackieCISTRUNK, LeonCLARK, JudithCOLASURDO, MarcoCZAP, AlexandraHAVENON, Adam deD'AMATO, SalvatoreSABBEN, CandiceTHOMAS, James OrtonDHARMADHIKARI, SushrutGRIMMETT, Kasey B.DMYTRIW, Adam A.ETHERTON, Mark R.EZEPUE, ChizobaFAROOQUI, MudassirFESKE, Steven K.FINK, LaurenGASIMOVA, UlviyyaREINER, PeggyGUZIK, Amy K.PARSONS, Mark W.HAKEMI, MaryamHOVINGH, MajestaKHAN, MuhibJILLELA, DineshKHATRI, RakeshKHAWAJA, Ayaz M.KHOURY, Naim N.KILEY, Nicole L.ROUANET, FrancoisKIM, Benny S.KOLIKONDA, Murali K.SINGHAL, ShalooKUHN, Anna LuisaLARA, StephanieLINARES, GuillermoLINFANTE, ItaloLUKOVITS, Timothy G.LYCAN, SarahMALE, Shailesh S.BOHMANN, Ferdinand O.MAALI, LaithMANCIN, JohnMASOUD, HeshamSLATER, Lee-AnneMOHAMED, Ghada A.MONTEIRO, AndreNAHAB, FadiNALLEBALLE, KrishnaORTEGA-GUTIERREZ, SantiagoPURI, Ajit S.BOSKAMP, StefanRADAIDEH, YazanRAHANGDALE, Rahul H.RAI, AnsaarRAMAKRISHNAN, PankajavalliMARTINS, Rodrigo TomaziniREDDY, Aravind B.ROJAS-SOTO, Diana M.ROMERO, Jose RafaelROST, Natalia S.ROTHSTEIN, AaronMBROH, JoshuaOMRAN, Setareh SalehiSHETH, Sunil A.SIDDIQUI, Adnan H.STAROSCIAK, Amy K.TARLOV, Nicholas E.ENZINGER, ChrisTAYLOR, Robert A.WANG, Michael J.WOLFE, JaredWONG, Ka-HoNAGEL, SimonHuynh Vu LeQuy Viet NguyenThong Nhu PhamTrung Thanh NguyenHoang Thi PhanMai Duy TonGATTRINGER, ThomasFISCHER, UrsMICHEL, PatrikSTRAMBO, DavideNOLTE, Christian H.MARTINS, Sheila O.ZAIDAT, Osama O.NOGUEIRA, Raul G.RAHMAN, AminurBONNET, ThomasLIGOT, NoemieRAEDT, Sylvie DeLEMMENS, RobinVANACKER, PeterVANDERVORST, FenneRINGLEB, Peter A.CONFORTO, Adriana BastosHIDALGO, Raquel C. T.NEVES, Luciana de OliveiraMARTINS, Rodrigo TargaCUERVO, Daissy Liliana MoraREBELLO, Leticia C.SANTIAGO, Igor BessaSILVA, Isabelle Lameirinhas daSAKELAROVA, TeodoraKALPACHKI, RosenLESAINE, EmilieALEXIEV, FilipCATANESE, LucianaCORA, Elena AdelaGOYAL, MayankHILL, Michael D.KELLY, Michael E.KHOSRAVANI, HoumanLAVOIE, PascalePEELING, LissaPIKULA, AleksandraROSENKRANZ, MichaelRIVERA, RodrigoCHEN, Hui-ShengCHEN, YiminHUO, XiaochuanMIAO, ZhongrongYANG, ShuiquanBEDEKOVIC, Marina RojeBRALIC, MarinaBUDINCEVIC, HrvojeCORREDOR-QUINTERO, Angel BasilioPOLI, SvenLARA-SARABIA, Osvaldo E.CABAL, MartinTENORA, DusanFIBRICH, PetrHERZIG, RomanHRABANOVSKA, EmanuelaHLINOVSKY, DavidJURAK, LubomirKADLCIKOVA, JanaKARPOWICZ, IgorTHOMALLA, GotzKLECKA, LukasKOVAR, MartinLAUER, DavidNEUMANN, JiriPALOUSKOVA, HanaREISER, MartinREKOVA, PetraROHAN, VladimirSKODA, OndrejSKORNA, MiroslavKARAPANAYIOTIDES, TheodorosSRAMEK, MartinZAKOVA, LenkaCHRISTENSEN, HanneDRENCK, NicolasIVERSEN, Helle KlingenbergTRUELSEN, Thomas ClementKOUTROULOU, IoannaKARGIOTIS, OdysseasPALAIODIMOU, LinaGUERRA, Jose Dominguo BarrientosHUDED, VikramMENON, BinduTSIVGOULIS, GeorgiosNAGENDRA, ShashankPRAJAPATI, ChintanSYLAJA, P. N.PRAMANA, Nyoman Angga KrishnaSANI, Achmad FirdausGHOREISHI, AbdorezaFARHOUDI, MehdiHOKMABADI, Elyar SadeghiRAYA, Tariq AbuKALMANOVICH, Shani AvneryI, Aaron LoochtanRONEN, LeviteSABETAY, Sergiu IonutACAMPA, MaurizioADAMI, AlessandroCASTELLAN, LucioLONGONI, MarcoORNELLO, RaffaeleRENIERI, LeonardoBIGLIANI, Claudia RollaROMOLI, MicheleDEMEESTERE, JelleSACCO, SimonaSALMAGGI, AndreaSANGALLI, DavideZINI, AndreaDOIJIRI, RyosukeFUKUDA, HirokiFUJINAKA, ToshiyukiFUJITA, KyoheiIMAMURA, HirotoshiSAKAI, NobuyukiUCHINO, KenKANAMARU, TakuyaKIMURA, NaotoKONO, RyuheiMIYAKE, KosukeSAKAGUCHI, ManabuSAKAI, KenichiroSONODA, KazutakaTODO, KenichiMIYASHITA, FumioTOKUDA, NaokiINOA, ViolizaMATSUMARU, YujiMATSUMOTO, ShojiOHARA, NobuyukiSHINDO, SeigoTAKENOBU, YoheiYOSHIMOTO, TakeshiTOYODA, KazunoriUWATOKO, TakeshiYAGITA, YoshikiYAMADA, TakehiroGOYAL, NitinYAMAMOTO, Nobuaki
Citation: NEUROLOGY, v.100, n.4, p.E408-E421, 2023
Abstract: Background and Objectives Declines in stroke admission, IV thrombolysis (IVT), and mechanical thrombectomy volumes were reported during the first wave of the COVID-19 pandemic. There is a paucity of data on the longer-term effect of the pandemic on stroke volumes over the course of a year and through the second wave of the pandemic. We sought to measure the effect of the COVID-19 pandemic on the volumes of stroke admissions, intracranial hemorrhage (ICH), IVT, and mechanical thrombectomy over a 1-year period at the onset of the pandemic (March 1, 2020, to February 28, 2021) compared with the immediately preceding year (March 1, 2019, to February 29, 2020). Methods We conducted a longitudinal retrospective study across 6 continents, 56 countries, and 275 stroke centers. We collected volume data for COVID-19 admissions and 4 stroke metrics: ischemic stroke admissions, ICH admissions, IVT treatments, and mechanical thrombectomy procedures. Diagnoses were identified by their ICD-10 codes or classifications in stroke databases. Results There were 148,895 stroke admissions in the 1 year immediately before compared with 138,453 admissions during the 1-year pandemic, representing a 7% decline (95% CI [95% CI 7.1-6.9]; p < 0.0001). ICH volumes declined from 29,585 to 28,156 (4.8% [5.1-4.6]; p < 0.0001) and IVT volume from 24,584 to 23,077 (6.1% [6.4-5.8]; p < 0.0001). Larger declines were observed at high-volume compared with low-volume centers (all p < 0.0001). There was no significant change in mechanical thrombectomy volumes (0.7% [0.6-0.9]; p = 0.49). Stroke was diagnosed in 1.3% [1.31-1.38] of 406,792 COVID-19 hospitalizations. SARS-CoV-2 infection was present in 2.9% ([2.82-2.97], 5,656/195,539) of all stroke hospitalizations. Discussion There was a global decline and shift to lower-volume centers of stroke admission volumes, ICH volumes, and IVT volumes during the 1st year of the COVID-19 pandemic compared with the prior year. Mechanical thrombectomy volumes were preserved. These results suggest preservation in the stroke care of higher severity of disease through the first pandemic year.
Appears in Collections:

Artigos e Materiais de Revistas Científicas - COVID-19
COVID-19

Artigos e Materiais de Revistas Científicas - HC/ICHC
Instituto Central - HC/ICHC

Artigos e Materiais de Revistas Científicas - LIM/15
LIM/15 - Laboratório de Investigação em Neurologia

Artigos e Materiais de Revistas Científicas - ODS/03
ODS/03 - Saúde e bem-estar


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